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172 related items for PubMed ID: 12915470

  • 1. Intrinsic susceptibility to misfolding of a hot-spot for Hirschsprung disease mutations in the ectodomain of RET.
    Kjaer S, Ibáñez CF.
    Hum Mol Genet; 2003 Sep 01; 12(17):2133-44. PubMed ID: 12915470
    [Abstract] [Full Text] [Related]

  • 2. Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET.
    Kjaer S, Ibáñez CF.
    J Biol Chem; 2003 Nov 28; 278(48):47898-904. PubMed ID: 14514671
    [Abstract] [Full Text] [Related]

  • 3. Direct interactions among Ret, GDNF and GFRalpha1 molecules reveal new insights into the assembly of a functional three-protein complex.
    Amoresano A, Incoronato M, Monti G, Pucci P, de Franciscis V, Cerchia L.
    Cell Signal; 2005 Jun 28; 17(6):717-27. PubMed ID: 15722196
    [Abstract] [Full Text] [Related]

  • 4. What do knockout models teach us about the enteric nervous system?
    Hagl CI, Holland-Cunz S, Schäfer KH.
    Eur J Pediatr Surg; 2003 Jun 28; 13(3):170-5. PubMed ID: 12939701
    [Abstract] [Full Text] [Related]

  • 5. Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells.
    Maeda K, Murakami H, Yoshida R, Ichihara M, Abe A, Hirai M, Murohara T, Takahashi M.
    Biochem Biophys Res Commun; 2004 Oct 08; 323(1):345-54. PubMed ID: 15351743
    [Abstract] [Full Text] [Related]

  • 6. Glial cell line-derived neurotrophic factor (GDNF) receptor alpha-1 (GFR alpha 1) is highly selective for GDNF versus artemin.
    Carmillo P, Dagø L, Day ES, Worley DS, Rossomando A, Walus L, Orozco O, Buckley C, Miller S, Tse A, Cate RL, Rosenblad C, Sah DW, Grønborg M, Whitty A.
    Biochemistry; 2005 Feb 22; 44(7):2545-54. PubMed ID: 15709767
    [Abstract] [Full Text] [Related]

  • 7. De novo mutation of GDNF, ligand for the RET/GDNFR-alpha receptor complex, in Hirschsprung disease.
    Ivanchuk SM, Myers SM, Eng C, Mulligan LM.
    Hum Mol Genet; 1996 Dec 22; 5(12):2023-6. PubMed ID: 8968758
    [Abstract] [Full Text] [Related]

  • 8. Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient.
    Angrist M, Bolk S, Halushka M, Lapchak PA, Chakravarti A.
    Nat Genet; 1996 Nov 22; 14(3):341-4. PubMed ID: 8896568
    [Abstract] [Full Text] [Related]

  • 9. The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation.
    Leppänen VM, Bespalov MM, Runeberg-Roos P, Puurand U, Merits A, Saarma M, Goldman A.
    EMBO J; 2004 Apr 07; 23(7):1452-62. PubMed ID: 15044950
    [Abstract] [Full Text] [Related]

  • 10. Soluble and bound forms of GFRalpha1 elicit different GDNF-independent neurite growth responses in primary sensory neurons.
    Mikaels-Edman A, Baudet C, Ernfors P.
    Dev Dyn; 2003 May 07; 227(1):27-34. PubMed ID: 12701096
    [Abstract] [Full Text] [Related]

  • 11. Identification of the key amino acids of glial cell line-derived neurotrophic factor family receptor alpha1 involved in its biological function.
    Wang LM, Zhang Q, Zhang Q, Zhu W, He C, Lu CL, Ding DF, Chen ZY.
    J Biol Chem; 2004 Jan 02; 279(1):109-16. PubMed ID: 14563851
    [Abstract] [Full Text] [Related]

  • 12. Expression of GFRalpha1 receptor splicing variants with different biochemical properties is modulated during kidney development.
    Charlet-Berguerand N, Le Hir H, Incoronato M, di Porzio U, Yu Y, Jing S, de Franciscis V, Thermes C.
    Cell Signal; 2004 Dec 02; 16(12):1425-34. PubMed ID: 15381258
    [Abstract] [Full Text] [Related]

  • 13. The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease.
    Bordeaux MC, Forcet C, Granger L, Corset V, Bidaud C, Billaud M, Bredesen DE, Edery P, Mehlen P.
    EMBO J; 2000 Aug 01; 19(15):4056-63. PubMed ID: 10921886
    [Abstract] [Full Text] [Related]

  • 14. GDNF, Ret, GFRalpha1 and 2 in the adult rat retino-tectal system after optic nerve transection.
    Lindqvist N, Peinado-Ramónn P, Vidal-Sanz M, Hallböök F.
    Exp Neurol; 2004 Jun 01; 187(2):487-99. PubMed ID: 15144875
    [Abstract] [Full Text] [Related]

  • 15. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 01; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 16. Functional characterization of mutations in the GDNF gene of patients with Hirschsprung disease.
    Eketjäll S, Ibáñez CF.
    Hum Mol Genet; 2002 Feb 01; 11(3):325-9. PubMed ID: 11823451
    [Abstract] [Full Text] [Related]

  • 17. The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.
    Mograbi B, Bocciardi R, Bourget I, Juhel T, Farahi-Far D, Romeo G, Ceccherini I, Rossi B.
    Mol Cell Biol; 2001 Oct 01; 21(20):6719-30. PubMed ID: 11564857
    [Abstract] [Full Text] [Related]

  • 18. Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site.
    Anders J, Kjar S, Ibáñez CF.
    J Biol Chem; 2001 Sep 21; 276(38):35808-17. PubMed ID: 11445581
    [Abstract] [Full Text] [Related]

  • 19. Mutation of the RET ligand, neurturin, supports multigenic inheritance in Hirschsprung disease.
    Doray B, Salomon R, Amiel J, Pelet A, Touraine R, Billaud M, Attié T, Bachy B, Munnich A, Lyonnet S.
    Hum Mol Genet; 1998 Sep 21; 7(9):1449-52. PubMed ID: 9700200
    [Abstract] [Full Text] [Related]

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