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318 related items for PubMed ID: 12917346
1. Morphine induces desensitization of insulin receptor signaling. Li Y, Eitan S, Wu J, Evans CJ, Kieffer B, Sun X, Polakiewicz RD. Mol Cell Biol; 2003 Sep; 23(17):6255-66. PubMed ID: 12917346 [Abstract] [Full Text] [Related]
2. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors. Inoue G, Cheatham B, Kahn CR. J Biol Chem; 1996 Nov 08; 271(45):28206-11. PubMed ID: 8910437 [Abstract] [Full Text] [Related]
3. Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptors. Daulhac L, Kowalski-Chauvel A, Pradayrol L, Vaysse N, Seva C. J Biol Chem; 1999 Jul 16; 274(29):20657-63. PubMed ID: 10400698 [Abstract] [Full Text] [Related]
4. Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart. Laviola L, Belsanti G, Davalli AM, Napoli R, Perrini S, Weir GC, Giorgino R, Giorgino F. Diabetes; 2001 Dec 16; 50(12):2709-20. PubMed ID: 11723053 [Abstract] [Full Text] [Related]
5. Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells. Hennige AM, Lammers R, Arlt D, Höppner W, Strack V, Niederfellner G, Seif FJ, Häring HU, Kellerer M. Mol Cell Endocrinol; 2000 Sep 25; 167(1-2):69-76. PubMed ID: 11000521 [Abstract] [Full Text] [Related]
6. Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling. Kim B, Cheng HL, Margolis B, Feldman EL. J Biol Chem; 1998 Dec 18; 273(51):34543-50. PubMed ID: 9852124 [Abstract] [Full Text] [Related]
7. Tyrosine phosphorylation-dependent and -independent role of Shc in the regulation of IGF-1-induced mitogenesis and glycogen synthesis. Sasaoka T, Ishiki M, Wada T, Hori H, Hirai H, Haruta T, Ishihara H, Kobayashi M. Endocrinology; 2001 Dec 18; 142(12):5226-35. PubMed ID: 11713219 [Abstract] [Full Text] [Related]
8. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes. Mur C, Valverde AM, Kahn CR, Benito M. Diabetes; 2002 Mar 18; 51(3):743-54. PubMed ID: 11872675 [Abstract] [Full Text] [Related]
9. Selective attenuation of metabolic branch of insulin receptor down-signaling by high glucose in a hepatoma cell line, HepG2 cells. Nakajima K, Yamauchi K, Shigematsu S, Ikeo S, Komatsu M, Aizawa T, Hashizume K. J Biol Chem; 2000 Jul 07; 275(27):20880-6. PubMed ID: 10764799 [Abstract] [Full Text] [Related]
10. Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation. Harada S, Smith RM, Smith JA, White MF, Jarett L. J Biol Chem; 1996 Nov 22; 271(47):30222-6. PubMed ID: 8939974 [Abstract] [Full Text] [Related]
11. Differential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteins. Solow BT, Harada S, Goldstein BJ, Smith JA, White MF, Jarett L. Mol Endocrinol; 1999 Oct 22; 13(10):1784-98. PubMed ID: 10517679 [Abstract] [Full Text] [Related]
12. Differential regulation of insulin receptor substrate-2 and mitogen-activated protein kinase tyrosine phosphorylation by phosphatidylinositol 3-kinase inhibitors in SH-SY5Y human neuroblastoma cells. Kim B, Leventhal PS, White MF, Feldman EL. Endocrinology; 1998 Dec 22; 139(12):4881-9. PubMed ID: 9832424 [Abstract] [Full Text] [Related]
13. Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control. Parpal S, Karlsson M, Thorn H, Strålfors P. J Biol Chem; 2001 Mar 30; 276(13):9670-8. PubMed ID: 11121405 [Abstract] [Full Text] [Related]
14. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway. Kurihara S, Hakuno F, Takahashi S. Endocr J; 2000 Dec 30; 47(6):739-51. PubMed ID: 11228049 [Abstract] [Full Text] [Related]
15. PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model. Weng LP, Smith WM, Brown JL, Eng C. Hum Mol Genet; 2001 Mar 15; 10(6):605-16. PubMed ID: 11230180 [Abstract] [Full Text] [Related]
16. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. Goalstone ML, Leitner JW, Berhanu P, Sharma PM, Olefsky JM, Draznin B. J Biol Chem; 2001 Apr 20; 276(16):12805-12. PubMed ID: 11278505 [Abstract] [Full Text] [Related]
17. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. Besset V, Scott RP, Ibáñez CF. J Biol Chem; 2000 Dec 15; 275(50):39159-66. PubMed ID: 10995764 [Abstract] [Full Text] [Related]
18. Functional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptors. Ishihara H, Sasaoka T, Ishiki M, Takata Y, Imamura T, Usui I, Langlois WJ, Sawa T, Kobayashi M. J Biol Chem; 1997 Apr 04; 272(14):9581-6. PubMed ID: 9083103 [Abstract] [Full Text] [Related]