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220 related items for PubMed ID: 12917419

  • 1. Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway.
    Calipel A, Lefevre G, Pouponnot C, Mouriaux F, Eychène A, Mascarelli F.
    J Biol Chem; 2003 Oct 24; 278(43):42409-18. PubMed ID: 12917419
    [Abstract] [Full Text] [Related]

  • 2. Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells.
    Lefevre G, Calipel A, Mouriaux F, Hecquet C, Malecaze F, Mascarelli F.
    Oncogene; 2003 Dec 04; 22(55):8813-22. PubMed ID: 14654778
    [Abstract] [Full Text] [Related]

  • 3. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T, Hikiba Y, Kanai F, Aragaki J, Tanaka Y, Imamura J, Imamura T, Ohta M, Ijichi H, Tateishi K, Kawakami T, Matsumura M, Kawabe T, Omata M.
    Cancer Res; 2004 May 15; 64(10):3428-35. PubMed ID: 15150094
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  • 4. Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling.
    Huntington JT, Shields JM, Der CJ, Wyatt CA, Benbow U, Slingluff CL, Brinckerhoff CE.
    J Biol Chem; 2004 Aug 06; 279(32):33168-76. PubMed ID: 15184373
    [Abstract] [Full Text] [Related]

  • 5. Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells.
    Calipel A, Mouriaux F, Glotin AL, Malecaze F, Faussat AM, Mascarelli F.
    J Biol Chem; 2006 Apr 07; 281(14):9238-50. PubMed ID: 16452469
    [Abstract] [Full Text] [Related]

  • 6. Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.
    Woods D, Cherwinski H, Venetsanakos E, Bhat A, Gysin S, Humbert M, Bray PF, Saylor VL, McMahon M.
    Mol Cell Biol; 2001 May 07; 21(9):3192-205. PubMed ID: 11287623
    [Abstract] [Full Text] [Related]

  • 7. SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant.
    Tsavachidou D, Coleman ML, Athanasiadis G, Li S, Licht JD, Olson MF, Weber BL.
    Cancer Res; 2004 Aug 15; 64(16):5556-9. PubMed ID: 15313890
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  • 10. Interferon-alpha2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism.
    Romerio F, Riva A, Zella D.
    Br J Cancer; 2000 Aug 15; 83(4):532-8. PubMed ID: 10945503
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  • 11. Mutations of the BRAF gene in human cancer.
    Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA.
    Nature; 2002 Jun 27; 417(6892):949-54. PubMed ID: 12068308
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  • 13. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
    Babchia N, Calipel A, Mouriaux F, Faussat AM, Mascarelli F.
    Invest Ophthalmol Vis Sci; 2008 Jun 27; 49(6):2348-56. PubMed ID: 18281615
    [Abstract] [Full Text] [Related]

  • 14. Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth.
    Hao H, Muniz-Medina VM, Mehta H, Thomas NE, Khazak V, Der CJ, Shields JM.
    Mol Cancer Ther; 2007 Aug 27; 6(8):2220-9. PubMed ID: 17699719
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  • 16. Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.
    Satyamoorthy K, Li G, Gerrero MR, Brose MS, Volpe P, Weber BL, Van Belle P, Elder DE, Herlyn M.
    Cancer Res; 2003 Feb 15; 63(4):756-9. PubMed ID: 12591721
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  • 19. Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling.
    Bhatt KV, Spofford LS, Aram G, McMullen M, Pumiglia K, Aplin AE.
    Oncogene; 2005 May 12; 24(21):3459-71. PubMed ID: 15735667
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  • 20. Identification of aurora kinase B and Wee1-like protein kinase as downstream targets of (V600E)B-RAF in melanoma.
    Sharma A, Madhunapantula SV, Gowda R, Berg A, Neves RI, Robertson GP.
    Am J Pathol; 2013 Apr 12; 182(4):1151-62. PubMed ID: 23416158
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