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133 related items for PubMed ID: 12926052

  • 1. Selective cancer cell apoptosis induced by FTY720; evidence for a Bcl-dependent pathway and impairment in ERK activity.
    Azuma H, Horie S, Muto S, Otsuki Y, Matsumoto K, Morimoto J, Gotoh R, Okuyama A, Suzuki S, Katsuoka Y, Takahara S.
    Anticancer Res; 2003; 23(4):3183-93. PubMed ID: 12926052
    [Abstract] [Full Text] [Related]

  • 2. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T, Azuma H, Kotake Y, Inamoto T, Takahara K, Ito Y, Kiyama S, Sakamoto T, Horie S, Muto S, Takahara S, Otsuki Y, Katsuoka Y.
    Anticancer Res; 2007; 27(1A):75-88. PubMed ID: 17352219
    [Abstract] [Full Text] [Related]

  • 3. Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment.
    Azuma H, Takahara S, Horie S, Muto S, Otsuki Y, Katsuoka Y.
    J Urol; 2003 Jun; 169(6):2372-7. PubMed ID: 12771800
    [Abstract] [Full Text] [Related]

  • 4. Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models.
    Azuma H, Takahara S, Ichimaru N, Wang JD, Itoh Y, Otsuki Y, Morimoto J, Fukui R, Hoshiga M, Ishihara T, Nonomura N, Suzuki S, Okuyama A, Katsuoka Y.
    Cancer Res; 2002 Mar 01; 62(5):1410-9. PubMed ID: 11888913
    [Abstract] [Full Text] [Related]

  • 5. FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
    Yasui H, Hideshima T, Raje N, Roccaro AM, Shiraishi N, Kumar S, Hamasaki M, Ishitsuka K, Tai YT, Podar K, Catley L, Mitsiades CS, Richardson PG, Albert R, Brinkmann V, Chauhan D, Anderson KC.
    Cancer Res; 2005 Aug 15; 65(16):7478-84. PubMed ID: 16103102
    [Abstract] [Full Text] [Related]

  • 6. Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway.
    Matsuda S, Minowa A, Suzuki S, Koyasu S.
    J Immunol; 1999 Mar 15; 162(6):3321-6. PubMed ID: 10092785
    [Abstract] [Full Text] [Related]

  • 7. FTY720, a synthetic compound from Isaria sinclairii, inhibits proliferation and induces apoptosis in pancreatic cancer cells.
    Shen Y, Cai M, Xia W, Liu J, Zhang Q, Xie H, Wang C, Wang X, Zheng S.
    Cancer Lett; 2007 Sep 08; 254(2):288-97. PubMed ID: 17462818
    [Abstract] [Full Text] [Related]

  • 8. FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Hung JH, Lu YS, Wang YC, Ma YH, Wang DS, Kulp SK, Muthusamy N, Byrd JC, Cheng AL, Chen CS.
    Cancer Res; 2008 Feb 15; 68(4):1204-12. PubMed ID: 18281497
    [Abstract] [Full Text] [Related]

  • 9. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 10. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL, Kuo PL, Lin LT, Lin CC.
    J Pharmacol Exp Ther; 2005 Apr 01; 313(1):333-44. PubMed ID: 15626723
    [Abstract] [Full Text] [Related]

  • 11. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R, Piperdi S, Gorlick R.
    Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278
    [Abstract] [Full Text] [Related]

  • 12. FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1.
    Pchejetski D, Bohler T, Brizuela L, Sauer L, Doumerc N, Golzio M, Salunkhe V, Teissié J, Malavaud B, Waxman J, Cuvillier O.
    Cancer Res; 2010 Nov 01; 70(21):8651-61. PubMed ID: 20959468
    [Abstract] [Full Text] [Related]

  • 13. The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells.
    Nguyen TT, Tran E, Nguyen TH, Do PT, Huynh TH, Huynh H.
    Carcinogenesis; 2004 May 01; 25(5):647-59. PubMed ID: 14688022
    [Abstract] [Full Text] [Related]

  • 14. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 01; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 15. Modulation of bcl-2 family proteins in MAPK independent apoptosis induced by a cdc25 phosphatase inhibitor Cpd 5 in renal cancer cells.
    Mizuno R, Oya M, Hara S, Matsumoto M, Horiguchi A, Ohigashi T, Marumo K, Murai M.
    Oncol Rep; 2005 Sep 01; 14(3):639-44. PubMed ID: 16077967
    [Abstract] [Full Text] [Related]

  • 16. [Effects of CPUY013, a novel Topo I inhibitor, on human gastric adenocarcinoma BGC823 cells in vitro and in vivo].
    Ji YB, Zhou JH, Zuo MX, You QD.
    Yao Xue Xue Bao; 2008 Aug 01; 43(8):811-8. PubMed ID: 18956773
    [Abstract] [Full Text] [Related]

  • 17. FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
    Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-Yokota E, Momoi T, Kasahara T.
    Biochem Biophys Res Commun; 2001 Feb 23; 281(2):282-8. PubMed ID: 11181042
    [Abstract] [Full Text] [Related]

  • 18. 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.
    Hsu TS, Chen C, Lee PT, Chiu SJ, Liu HF, Tsai CC, Chao JI.
    Cancer Chemother Pharmacol; 2008 Oct 23; 62(5):799-808. PubMed ID: 18193228
    [Abstract] [Full Text] [Related]

  • 19. Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism.
    Shibata MA, Ito Y, Morimoto J, Otsuki Y.
    Carcinogenesis; 2004 Oct 23; 25(10):1887-98. PubMed ID: 15180944
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.
    Jazirehi AR, Vega MI, Chatterjee D, Goodglick L, Bonavida B.
    Cancer Res; 2004 Oct 01; 64(19):7117-26. PubMed ID: 15466208
    [Abstract] [Full Text] [Related]

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