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301 related items for PubMed ID: 12928390

  • 1. TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR.
    Holmberg K, Mariathasan S, Ohteki T, Ohashi PS, Gascoigne NR.
    J Immunol; 2003 Sep 01; 171(5):2427-34. PubMed ID: 12928390
    [Abstract] [Full Text] [Related]

  • 2. Peptidic termini play a significant role in TCR recognition.
    Wang B, Sharma A, Maile R, Saad M, Collins EJ, Frelinger JA.
    J Immunol; 2002 Sep 15; 169(6):3137-45. PubMed ID: 12218131
    [Abstract] [Full Text] [Related]

  • 3. Potent T cell agonism mediated by a very rapid TCR/pMHC interaction.
    Boulter JM, Schmitz N, Sewell AK, Godkin AJ, Bachmann MF, Gallimore AM.
    Eur J Immunol; 2007 Mar 15; 37(3):798-806. PubMed ID: 17295390
    [Abstract] [Full Text] [Related]

  • 4. Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture.
    Kersh GJ, Engle DL, Williams CB, Allen PM.
    J Immunol; 2000 Jun 01; 164(11):5675-82. PubMed ID: 10820243
    [Abstract] [Full Text] [Related]

  • 5. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.
    Huang J, Zarnitsyna VI, Liu B, Edwards LJ, Jiang N, Evavold BD, Zhu C.
    Nature; 2010 Apr 08; 464(7290):932-6. PubMed ID: 20357766
    [Abstract] [Full Text] [Related]

  • 6. Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR.
    Denkberg G, Cohen CJ, Reiter Y.
    J Immunol; 2001 Jul 01; 167(1):270-6. PubMed ID: 11418659
    [Abstract] [Full Text] [Related]

  • 7. Modulation of T cell function by TCR/pMHC binding kinetics.
    Carreño LJ, González PA, Kalergis AM.
    Immunobiology; 2006 Jul 01; 211(1-2):47-64. PubMed ID: 16446170
    [Abstract] [Full Text] [Related]

  • 8. A physiological ligand of positive selection is recognized as a weak agonist.
    Berg RE, Irion S, Kattman S, Princiotta MF, Staerz UD.
    J Immunol; 2000 Oct 15; 165(8):4209-16. PubMed ID: 11035053
    [Abstract] [Full Text] [Related]

  • 9. Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement.
    Kerry SE, Buslepp J, Cramer LA, Maile R, Hensley LL, Nielsen AI, Kavathas P, Vilen BJ, Collins EJ, Frelinger JA.
    J Immunol; 2003 Nov 01; 171(9):4493-503. PubMed ID: 14568922
    [Abstract] [Full Text] [Related]

  • 10. Decreased binding of peptides-MHC class I (pMHC) multimeric complexes to CD8 affects their binding avidity for the TCR but does not significantly impact on pMHC/TCR dissociation rate.
    Dutoit V, Guillaume P, Ayyoub M, Hesdorffer CS, Luescher IF, Valmori D.
    J Immunol; 2003 May 15; 170(10):5110-7. PubMed ID: 12734357
    [Abstract] [Full Text] [Related]

  • 11. Homology between an alloantigen and a self MHC allele calibrates the avidity of the alloreactive T cell repertoire independent of TCR affinity.
    Hornell TM, Myers N, Hansen TH, Connolly JM.
    J Immunol; 2003 May 01; 170(9):4506-14. PubMed ID: 12707327
    [Abstract] [Full Text] [Related]

  • 12. T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.
    González PA, Carreño LJ, Coombs D, Mora JE, Palmieri E, Goldstein B, Nathenson SG, Kalergis AM.
    Proc Natl Acad Sci U S A; 2005 Mar 29; 102(13):4824-9. PubMed ID: 15772168
    [Abstract] [Full Text] [Related]

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  • 14. Dissecting TCR-MHC/peptide complex interactions with A2/peptide multimers incorporating tumor antigen peptide variants: crucial role of interaction kinetics on functional outcomes.
    Dutoit V, Guillaume P, Cerottini JC, Romero P, Valmori D.
    Eur J Immunol; 2002 Nov 29; 32(11):3285-93. PubMed ID: 12555674
    [Abstract] [Full Text] [Related]

  • 15. High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.
    Buslepp J, Kerry SE, Loftus D, Frelinger JA, Appella E, Collins EJ.
    J Immunol; 2003 Jan 01; 170(1):373-83. PubMed ID: 12496422
    [Abstract] [Full Text] [Related]

  • 16. Limits to the differential avidity model of T cell selection in the thymus.
    Girao C, Hu Q, Sun J, Ashton-Rickardt PG.
    J Immunol; 1997 Nov 01; 159(9):4205-11. PubMed ID: 9379014
    [Abstract] [Full Text] [Related]

  • 17. Distinct T cell interactions with HLA class II tetramers characterize a spectrum of TCR affinities in the human antigen-specific T cell response.
    Reichstetter S, Ettinger RA, Liu AW, Gebe JA, Nepom GT, Kwok WW.
    J Immunol; 2000 Dec 15; 165(12):6994-8. PubMed ID: 11120826
    [Abstract] [Full Text] [Related]

  • 18. A low affinity TCR ligand restores positive selection of CD8+ T cells in vivo.
    Stefanski HE, Mayerova D, Jameson SC, Hogquist KA.
    J Immunol; 2001 Jun 01; 166(11):6602-7. PubMed ID: 11359813
    [Abstract] [Full Text] [Related]

  • 19. Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo.
    Maile R, Siler CA, Kerry SE, Midkiff KE, Collins EJ, Frelinger JA.
    J Immunol; 2005 Jan 15; 174(2):619-27. PubMed ID: 15634879
    [Abstract] [Full Text] [Related]

  • 20. Antibodies directed against the MHC-I molecule H-2Dd complexed with an antigenic peptide: similarities to a T cell receptor with the same specificity.
    Polakova K, Plaksin D, Chung DH, Belyakov IM, Berzofsky JA, Margulies DH.
    J Immunol; 2000 Nov 15; 165(10):5703-12. PubMed ID: 11067928
    [Abstract] [Full Text] [Related]

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