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484 related items for PubMed ID: 12934075

  • 1. Caspase-9 is activated in a cytochrome c-independent manner early during TNFalpha-induced apoptosis in murine cells.
    McDonnell MA, Wang D, Khan SM, Vander Heiden MG, Kelekar A.
    Cell Death Differ; 2003 Sep; 10(9):1005-15. PubMed ID: 12934075
    [Abstract] [Full Text] [Related]

  • 2. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells.
    Hasenjäger A, Gillissen B, Müller A, Normand G, Hemmati PG, Schuler M, Dörken B, Daniel PT.
    Oncogene; 2004 Jun 03; 23(26):4523-35. PubMed ID: 15064710
    [Abstract] [Full Text] [Related]

  • 3. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.
    Perkins CL, Fang G, Kim CN, Bhalla KN.
    Cancer Res; 2000 Mar 15; 60(6):1645-53. PubMed ID: 10749135
    [Abstract] [Full Text] [Related]

  • 4. Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
    Izeradjene K, Douglas L, Tillman DM, Delaney AB, Houghton JA.
    Cancer Res; 2005 Aug 15; 65(16):7436-45. PubMed ID: 16103097
    [Abstract] [Full Text] [Related]

  • 5. Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway.
    Maddika S, Booy EP, Johar D, Gibson SB, Ghavami S, Los M.
    J Cell Sci; 2005 Oct 01; 118(Pt 19):4485-93. PubMed ID: 16179607
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.
    Schmelz K, Wieder T, Tamm I, Müller A, Essmann F, Geilen CC, Schulze-Osthoff K, Dörken B, Daniel PT.
    Oncogene; 2004 Sep 02; 23(40):6743-59. PubMed ID: 15273737
    [Abstract] [Full Text] [Related]

  • 7. Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.
    Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.
    Oncogene; 2006 Dec 07; 25(58):7618-34. PubMed ID: 16983347
    [Abstract] [Full Text] [Related]

  • 8. Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2.
    Dirsch VM, Stuppner H, Vollmar AM.
    Cancer Res; 2001 Aug 01; 61(15):5817-23. PubMed ID: 11479221
    [Abstract] [Full Text] [Related]

  • 9. Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells.
    Chen J, Mehta JL, Haider N, Zhang X, Narula J, Li D.
    Circ Res; 2004 Feb 20; 94(3):370-6. PubMed ID: 14684629
    [Abstract] [Full Text] [Related]

  • 10. Bax and Bid act in synergy to bring about T11TS-mediated glioma apoptosis via the release of mitochondrial cytochrome c and subsequent caspase activation.
    Bhattacharjee M, Acharya S, Ghosh A, Sarkar P, Chatterjee S, Kumar P, Chaudhuri S.
    Int Immunol; 2008 Dec 20; 20(12):1489-505. PubMed ID: 18931364
    [Abstract] [Full Text] [Related]

  • 11. Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation.
    Schmitt E, Paquet C, Beauchemin M, Bertrand R.
    Oncogene; 2004 May 13; 23(22):3915-31. PubMed ID: 15048082
    [Abstract] [Full Text] [Related]

  • 12. Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and caspase-9.
    Tichý A, Záskodová D, Pejchal J, Rezácová M, Osterreicher J, Vávrová J, Cerman J.
    Int J Radiat Biol; 2008 Jun 13; 84(6):523-30. PubMed ID: 18470751
    [Abstract] [Full Text] [Related]

  • 13. Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.
    von Haefen C, Wieder T, Essmann F, Schulze-Osthoff K, Dörken B, Daniel PT.
    Oncogene; 2003 Apr 17; 22(15):2236-47. PubMed ID: 12700660
    [Abstract] [Full Text] [Related]

  • 14. Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation.
    Eldering E, Mackus WJ, Derks IA, Evers LM, Beuling E, Teeling P, Lens SM, van Oers MH, van Lier RA.
    Eur J Immunol; 2004 Jul 17; 34(7):1950-60. PubMed ID: 15214043
    [Abstract] [Full Text] [Related]

  • 15. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
    Izeradjene K, Douglas L, Delaney AB, Houghton JA.
    Cancer Res; 2004 Nov 01; 64(21):8036-44. PubMed ID: 15520213
    [Abstract] [Full Text] [Related]

  • 16. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 17. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 18. Bak but not Bax is essential for Bcl-xS-induced apoptosis.
    Lindenboim L, Kringel S, Braun T, Borner C, Stein R.
    Cell Death Differ; 2005 Jul 22; 12(7):713-23. PubMed ID: 15861188
    [Abstract] [Full Text] [Related]

  • 19. Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
    Perchellet EM, Wang Y, Weber RL, Sperfslage BJ, Lou K, Crossland J, Hua DH, Perchellet JP.
    Biochem Pharmacol; 2004 Feb 01; 67(3):523-37. PubMed ID: 15037204
    [Abstract] [Full Text] [Related]

  • 20. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH, Lee BH, Lim SC.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1845-55. PubMed ID: 15450950
    [Abstract] [Full Text] [Related]

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