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222 related items for PubMed ID: 12934083

  • 1. Stress-induced apoptosis is impaired in cells with a lysosomal targeting defect but is not affected in cells synthesizing a catalytically inactive cathepsin D.
    Tardy C, Tyynelä J, Hasilik A, Levade T, Andrieu-Abadie N.
    Cell Death Differ; 2003 Sep; 10(9):1090-100. PubMed ID: 12934083
    [Abstract] [Full Text] [Related]

  • 2. Sensitization to the lysosomal cell death pathway upon immortalization and transformation.
    Fehrenbacher N, Gyrd-Hansen M, Poulsen B, Felbor U, Kallunki T, Boes M, Weber E, Leist M, Jäättelä M.
    Cancer Res; 2004 Aug 01; 64(15):5301-10. PubMed ID: 15289336
    [Abstract] [Full Text] [Related]

  • 3. Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells.
    Zang Y, Beard RL, Chandraratna RA, Kang JX.
    Cell Death Differ; 2001 May 01; 8(5):477-85. PubMed ID: 11423908
    [Abstract] [Full Text] [Related]

  • 4. Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine.
    Johansson AC, Steen H, Ollinger K, Roberg K.
    Cell Death Differ; 2003 Nov 01; 10(11):1253-9. PubMed ID: 14576777
    [Abstract] [Full Text] [Related]

  • 5. Endosomal-lysosomal proteolysis mediates death signalling by TNFalpha, not by etoposide, in L929 fibrosarcoma cells: evidence for an active role of cathepsin D.
    Démoz M, Castino R, Cesaro P, Baccino FM, Bonelli G, Isidoro C.
    Biol Chem; 2002 Nov 01; 383(7-8):1237-48. PubMed ID: 12437111
    [Abstract] [Full Text] [Related]

  • 6. The catalytically inactive precursor of cathepsin D induces apoptosis in human fibroblasts and HeLa cells.
    Schestkowa O, Geisel D, Jacob R, Hasilik A.
    J Cell Biochem; 2007 Aug 15; 101(6):1558-66. PubMed ID: 17340625
    [Abstract] [Full Text] [Related]

  • 7. Increase in ceramide level alters the lysosomal targeting of cathepsin D prior to onset of apoptosis in HT-29 colon cancer cells.
    De Stefanis D, Reffo P, Bonelli G, Baccino FM, Sala G, Ghidoni R, Codogno P, Isidoro C.
    Biol Chem; 2002 Jun 15; 383(6):989-99. PubMed ID: 12222689
    [Abstract] [Full Text] [Related]

  • 8. Enhanced cystatin C and lysosomal protease expression following 6-hydroxydopamine exposure.
    Lee DC, Close FT, Goodman CB, Jackson IM, Wight-Mason C, Wells LM, Womble TA, Palm DE.
    Neurotoxicology; 2006 Mar 15; 27(2):260-76. PubMed ID: 16414118
    [Abstract] [Full Text] [Related]

  • 9. Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation.
    Heinrich M, Neumeyer J, Jakob M, Hallas C, Tchikov V, Winoto-Morbach S, Wickel M, Schneider-Brachert W, Trauzold A, Hethke A, Schütze S.
    Cell Death Differ; 2004 May 15; 11(5):550-63. PubMed ID: 14739942
    [Abstract] [Full Text] [Related]

  • 10. Role of lysosomal cathepsins in naphthazarin- and Fas-induced apoptosis in oral squamous cell carcinoma cells.
    Johansson AC, Norberg-Spaak L, Roberg K.
    Acta Otolaryngol; 2006 Jan 15; 126(1):70-81. PubMed ID: 16308258
    [Abstract] [Full Text] [Related]

  • 11. Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation.
    Shibata M, Kanamori S, Isahara K, Ohsawa Y, Konishi A, Kametaka S, Watanabe T, Ebisu S, Ishido K, Kominami E, Uchiyama Y.
    Biochem Biophys Res Commun; 1998 Oct 09; 251(1):199-203. PubMed ID: 9790930
    [Abstract] [Full Text] [Related]

  • 12. Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.
    Wu GS, Saftig P, Peters C, El-Deiry WS.
    Oncogene; 1998 Apr 30; 16(17):2177-83. PubMed ID: 9619826
    [Abstract] [Full Text] [Related]

  • 13. Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.
    Fehrenbacher N, Bastholm L, Kirkegaard-Sørensen T, Rafn B, Bøttzauw T, Nielsen C, Weber E, Shirasawa S, Kallunki T, Jäättelä M.
    Cancer Res; 2008 Aug 15; 68(16):6623-33. PubMed ID: 18701486
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes.
    Ollinger K.
    Arch Biochem Biophys; 2000 Jan 15; 373(2):346-51. PubMed ID: 10620358
    [Abstract] [Full Text] [Related]

  • 15. Methamphetamine induces autophagy and apoptosis in a mesencephalic dopaminergic neuronal culture model: role of cathepsin-D in methamphetamine-induced apoptotic cell death.
    Kanthasamy A, Anantharam V, Ali SF, Kanthasamy AG.
    Ann N Y Acad Sci; 2006 Aug 15; 1074():234-44. PubMed ID: 17105920
    [Abstract] [Full Text] [Related]

  • 16. The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells.
    Burek C, Roth J, Koch HG, Harzer K, Los M, Schulze-Osthoff K.
    Oncogene; 2001 Oct 04; 20(45):6493-502. PubMed ID: 11641773
    [Abstract] [Full Text] [Related]

  • 17. JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways.
    Dietrich N, Thastrup J, Holmberg C, Gyrd-Hansen M, Fehrenbacher N, Lademann U, Lerdrup M, Herdegen T, Jäättelä M, Kallunki T.
    Cell Death Differ; 2004 Mar 04; 11(3):301-13. PubMed ID: 14685158
    [Abstract] [Full Text] [Related]

  • 18. Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts.
    Roberg K, Kågedal K, Ollinger K.
    Am J Pathol; 2002 Jul 04; 161(1):89-96. PubMed ID: 12107093
    [Abstract] [Full Text] [Related]

  • 19. Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha.
    Deiss LP, Galinka H, Berissi H, Cohen O, Kimchi A.
    EMBO J; 1996 Aug 01; 15(15):3861-70. PubMed ID: 8670891
    [Abstract] [Full Text] [Related]

  • 20. Decreased apoptotic response of inclusion-cell disease fibroblasts: a consequence of lysosomal enzyme missorting?
    Terman A, Neuzil J, Kågedal K, Ollinger K, Brunk UT.
    Exp Cell Res; 2002 Mar 10; 274(1):9-15. PubMed ID: 11855852
    [Abstract] [Full Text] [Related]


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