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189 related items for PubMed ID: 12934099

  • 1. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma.
    Amin HM, Medeiros LJ, Ma Y, Feretzaki M, Das P, Leventaki V, Rassidakis GZ, O'Connor SL, McDonnell TJ, Lai R.
    Oncogene; 2003 Aug 21; 22(35):5399-407. PubMed ID: 12934099
    [Abstract] [Full Text] [Related]

  • 2. Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma.
    Han Y, Amin HM, Frantz C, Franko B, Lee J, Lin Q, Lai R.
    Leukemia; 2006 Sep 21; 20(9):1602-9. PubMed ID: 16871283
    [Abstract] [Full Text] [Related]

  • 3. JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells.
    Shi X, Franko B, Frantz C, Amin HM, Lai R.
    Br J Haematol; 2006 Oct 21; 135(1):26-32. PubMed ID: 16939498
    [Abstract] [Full Text] [Related]

  • 4. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
    Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R.
    Oncogene; 2004 Jul 15; 23(32):5426-34. PubMed ID: 15184887
    [Abstract] [Full Text] [Related]

  • 5. Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma.
    Cho-Vega JH, Rassidakis GZ, Amin HM, Tsioli P, Spurgers K, Remache YK, Vega F, Goy AH, Gilles F, Medeiros LJ.
    Leukemia; 2004 Nov 15; 18(11):1872-8. PubMed ID: 15385932
    [Abstract] [Full Text] [Related]

  • 6. Jak3 activation is significantly associated with ALK expression in anaplastic large cell lymphoma.
    Lai R, Rassidakis GZ, Lin Q, Atwell C, Medeiros LJ, Amin HM.
    Hum Pathol; 2005 Sep 15; 36(9):939-44. PubMed ID: 16153455
    [Abstract] [Full Text] [Related]

  • 7. Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma.
    Han Y, Amin HM, Franko B, Frantz C, Shi X, Lai R.
    Blood; 2006 Oct 15; 108(8):2796-803. PubMed ID: 16825495
    [Abstract] [Full Text] [Related]

  • 8. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death.
    Zamo A, Chiarle R, Piva R, Howes J, Fan Y, Chilosi M, Levy DE, Inghirami G.
    Oncogene; 2002 Feb 07; 21(7):1038-47. PubMed ID: 11850821
    [Abstract] [Full Text] [Related]

  • 9. Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
    Lai R, Rassidakis GZ, Medeiros LJ, Ramdas L, Goy AH, Cutler C, Fujio Y, Kunisada K, Amin HM, Gilles F.
    Am J Pathol; 2004 Jun 07; 164(6):2251-8. PubMed ID: 15161657
    [Abstract] [Full Text] [Related]

  • 10. Differential expression of cyclin D3 in ALK+ and ALK- anaplastic large cell lymphoma.
    Dalton RR, Rassidakis GZ, Atwell C, Wang S, Oyarzo MP, Medeiros LJ.
    Hum Pathol; 2005 Jul 07; 36(7):806-11. PubMed ID: 16084951
    [Abstract] [Full Text] [Related]

  • 11. Intrinsic apoptotic pathway in anaplastic large cell lymphoma.
    Oyarzo MP, Drakos E, Atwell C, Amin HM, Medeiros LJ, Rassidakis GZ.
    Hum Pathol; 2006 Jul 07; 37(7):874-82. PubMed ID: 16784988
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3.
    Marzec M, Kasprzycka M, Ptasznik A, Wlodarski P, Zhang Q, Odum N, Wasik MA.
    Lab Invest; 2005 Dec 07; 85(12):1544-54. PubMed ID: 16170336
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of tyrosine kinase activity induces caspase-dependent apoptosis in anaplastic large cell lymphoma with NPM-ALK (p80) fusion protein.
    Ergin M, Denning MF, Izban KF, Amin HM, Martinez RL, Saeed S, Alkan S.
    Exp Hematol; 2001 Sep 07; 29(9):1082-90. PubMed ID: 11532349
    [Abstract] [Full Text] [Related]

  • 14. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells.
    Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Grammatikakis I, Rassidakis GZ, Zhang W, Fujio Y, Kunisada K, Hamilton SR, Amin HM.
    Am J Pathol; 2005 Oct 07; 167(4):969-80. PubMed ID: 16192633
    [Abstract] [Full Text] [Related]

  • 15. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma.
    Christensen JG, Zou HY, Arango ME, Li Q, Lee JH, McDonnell SR, Yamazaki S, Alton GR, Mroczkowski B, Los G.
    Mol Cancer Ther; 2007 Dec 07; 6(12 Pt 1):3314-22. PubMed ID: 18089725
    [Abstract] [Full Text] [Related]

  • 16. NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma.
    Leventaki V, Drakos E, Medeiros LJ, Lim MS, Elenitoba-Johnson KS, Claret FX, Rassidakis GZ.
    Blood; 2007 Sep 01; 110(5):1621-30. PubMed ID: 17416736
    [Abstract] [Full Text] [Related]

  • 17. Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma.
    Khoury JD, Medeiros LJ, Rassidakis GZ, Yared MA, Tsioli P, Leventaki V, Schmitt-Graeff A, Herling M, Amin HM, Lai R.
    Clin Cancer Res; 2003 Sep 01; 9(10 Pt 1):3692-9. PubMed ID: 14506160
    [Abstract] [Full Text] [Related]

  • 18. Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma.
    Zhang Q, Raghunath PN, Xue L, Majewski M, Carpentieri DF, Odum N, Morris S, Skorski T, Wasik MA.
    J Immunol; 2002 Jan 01; 168(1):466-74. PubMed ID: 11751994
    [Abstract] [Full Text] [Related]

  • 19. Crizotinib (PF-2341066) induces apoptosis due to downregulation of pSTAT3 and BCL-2 family proteins in NPM-ALK(+) anaplastic large cell lymphoma.
    Hamedani FS, Cinar M, Mo Z, Cervania MA, Amin HM, Alkan S.
    Leuk Res; 2014 Apr 01; 38(4):503-8. PubMed ID: 24486291
    [Abstract] [Full Text] [Related]

  • 20. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.
    Voena C, Conte C, Ambrogio C, Boeri Erba E, Boccalatte F, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.
    Cancer Res; 2007 May 01; 67(9):4278-86. PubMed ID: 17483340
    [Abstract] [Full Text] [Related]

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