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Journal Abstract Search


165 related items for PubMed ID: 12935312

  • 1. Structure-activity relationship of 3-methyl-1-phenyl-2-pyrazolin-5-one (edaravone).
    Watanabe K, Morinaka Y, Iseki K, Watanabe T, Yuki S, Nishi H.
    Redox Rep; 2003; 8(3):151-5. PubMed ID: 12935312
    [Abstract] [Full Text] [Related]

  • 2. Radical scavenger edaravone developed for clinical use ameliorates ischemia/reperfusion injury in rat kidney.
    Doi K, Suzuki Y, Nakao A, Fujita T, Noiri E.
    Kidney Int; 2004 May; 65(5):1714-23. PubMed ID: 15086910
    [Abstract] [Full Text] [Related]

  • 3. Pulse radiolysis study on free radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one). 2: A comparative study on edaravone derivatives.
    Hata K, Lin M, Katsumura Y, Muroya Y, Fu H, Yamashita S, Nakagawa H.
    J Radiat Res; 2011 May; 52(1):15-23. PubMed ID: 21139328
    [Abstract] [Full Text] [Related]

  • 4. Edaravone inhibits lipid peroxidation in neonatal hypoxic-ischemic rats: an in vivo microdialysis study.
    Noor JI, Ueda Y, Ikeda T, Ikenoue T.
    Neurosci Lett; 2007 Feb 27; 414(1):5-9. PubMed ID: 17280782
    [Abstract] [Full Text] [Related]

  • 5. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.
    Kawasaki T, Ishihara K, Ago Y, Baba A, Matsuda T.
    J Pharmacol Exp Ther; 2007 Jul 27; 322(1):274-81. PubMed ID: 17429058
    [Abstract] [Full Text] [Related]

  • 6. Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats.
    Tomatsuri N, Yoshida N, Takagi T, Katada K, Isozaki Y, Imamoto E, Uchiyama K, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T.
    Int J Mol Med; 2004 Jan 27; 13(1):105-9. PubMed ID: 14654979
    [Abstract] [Full Text] [Related]

  • 7. Repeated edaravone treatment reduces oxidative cell damage in rat brain induced by middle cerebral artery occlusion.
    Yamamoto Y, Yanagisawa M, Tak NW, Watanabe K, Takahashi C, Fujisawa A, Kashiba M, Tanaka M.
    Redox Rep; 2009 Jan 27; 14(6):251-8. PubMed ID: 20003710
    [Abstract] [Full Text] [Related]

  • 8. [Research and development of the free radical scavenger edaravone as a neuroprotectant].
    Watanabe T, Tanaka M, Watanabe K, Takamatsu Y, Tobe A.
    Yakugaku Zasshi; 2004 Mar 27; 124(3):99-111. PubMed ID: 15049127
    [Abstract] [Full Text] [Related]

  • 9. Effect of the free radical scavenger, 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), on hypoxia-ischemia-induced brain injury in neonatal rats.
    Ikeda T, Xia YX, Kaneko M, Sameshima H, Ikenoue T.
    Neurosci Lett; 2002 Aug 23; 329(1):33-6. PubMed ID: 12161256
    [Abstract] [Full Text] [Related]

  • 10. A theoretical investigation on DPPH radical-scavenging mechanism of edaravone.
    Wang LF, Zhang HY.
    Bioorg Med Chem Lett; 2003 Nov 03; 13(21):3789-92. PubMed ID: 14552780
    [Abstract] [Full Text] [Related]

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  • 12. Improvement of postischemic dopaminergic dysfunction by edaravone, a free radical scavenger.
    Akiyama Y, Miwa S.
    J Pharmacol Sci; 2007 May 03; 104(1):99-102. PubMed ID: 17452805
    [Abstract] [Full Text] [Related]

  • 13. Edaravone, a potent free radical scavenger, reacts with peroxynitrite to produce predominantly 4-NO-edaravone.
    Fujisawa A, Yamamoto Y.
    Redox Rep; 2016 May 03; 21(3):98-103. PubMed ID: 26196041
    [Abstract] [Full Text] [Related]

  • 14. Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.
    Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.
    J Pharmacol Exp Ther; 2009 May 03; 329(2):687-98. PubMed ID: 19201991
    [Abstract] [Full Text] [Related]

  • 15. The reaction rate of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with hydroxyl radical.
    Abe S, Kirima K, Tsuchiya K, Okamoto M, Hasegawa T, Houchi H, Yoshizumi M, Tamaki T.
    Chem Pharm Bull (Tokyo); 2004 Feb 03; 52(2):186-91. PubMed ID: 14758002
    [Abstract] [Full Text] [Related]

  • 16. Development of cardiac dysfunction induced by repetitive transient myocardial ischemia is inhibited by edaravone in conscious rats.
    Toyota E, Miyamoto Y, Imai K, Neishi Y, Kawamoto T, Okura H, Yoshida K.
    Clin Exp Pharmacol Physiol; 2009 Sep 03; 36(9):e20-5. PubMed ID: 19473343
    [Abstract] [Full Text] [Related]

  • 17. The therapeutic efficacy of edaravone in extensively burned rats.
    Koizumi T, Tanaka H, Sakaki S, Shimazaki S.
    Arch Surg; 2006 Oct 03; 141(10):992-5. PubMed ID: 17043277
    [Abstract] [Full Text] [Related]

  • 18. Edaravone prevented deteriorated cardiac function after myocardial ischemia-reperfusion via inhibiting lipid peroxidation in rat.
    Yagi H, Horinaka S, Matsuoka H.
    J Cardiovasc Pharmacol; 2005 Jul 03; 46(1):46-51. PubMed ID: 15965354
    [Abstract] [Full Text] [Related]

  • 19. Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats.
    Saini AK, Patel RJ, Sharma SS, H S AK.
    Pharmacol Res; 2006 Jul 03; 54(1):6-10. PubMed ID: 16545576
    [Abstract] [Full Text] [Related]

  • 20. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases.
    Higashi Y, Jitsuiki D, Chayama K, Yoshizumi M.
    Recent Pat Cardiovasc Drug Discov; 2006 Jan 03; 1(1):85-93. PubMed ID: 18221078
    [Abstract] [Full Text] [Related]


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