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416 related items for PubMed ID: 12941691

  • 1. Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization.
    Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ.
    EMBO J; 2003 Sep 01; 22(17):4385-99. PubMed ID: 12941691
    [Abstract] [Full Text] [Related]

  • 2. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 3. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli.
    Arnoult D, Parone P, Martinou JC, Antonsson B, Estaquier J, Ameisen JC.
    J Cell Biol; 2002 Dec 23; 159(6):923-9. PubMed ID: 12486111
    [Abstract] [Full Text] [Related]

  • 5. Bisphenol A diglycidyl ether-induced apoptosis involves Bax/Bid-dependent mitochondrial release of apoptosis-inducing factor (AIF), cytochrome c and Smac/DIABLO.
    Fehlberg S, Gregel CM, Göke A, Göke R.
    Br J Pharmacol; 2003 Jun 23; 139(3):495-500. PubMed ID: 12788809
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K.
    Sundararajan R, Cuconati A, Nelson D, White E.
    J Biol Chem; 2001 Nov 30; 276(48):45120-7. PubMed ID: 11571294
    [Abstract] [Full Text] [Related]

  • 7. Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
    Wang GQ, Wieckowski E, Goldstein LA, Gastman BR, Rabinovitz A, Gambotto A, Li S, Fang B, Yin XM, Rabinowich H.
    J Exp Med; 2001 Nov 05; 194(9):1325-37. PubMed ID: 11696597
    [Abstract] [Full Text] [Related]

  • 8. A role for mitochondrial Bak in apoptotic response to anticancer drugs.
    Wang GQ, Gastman BR, Wieckowski E, Goldstein LA, Gambotto A, Kim TH, Fang B, Rabinovitz A, Yin XM, Rabinowich H.
    J Biol Chem; 2001 Sep 07; 276(36):34307-17. PubMed ID: 11447222
    [Abstract] [Full Text] [Related]

  • 9. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.
    Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.
    J Biol Chem; 2002 Jun 21; 277(25):22781-8. PubMed ID: 11929871
    [Abstract] [Full Text] [Related]

  • 10. Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity.
    Robertson JD, Gogvadze V, Kropotov A, Vakifahmetoglu H, Zhivotovsky B, Orrenius S.
    EMBO Rep; 2004 Jun 21; 5(6):643-8. PubMed ID: 15153933
    [Abstract] [Full Text] [Related]

  • 11. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.
    Mol Cell; 2001 Sep 21; 8(3):705-11. PubMed ID: 11583631
    [Abstract] [Full Text] [Related]

  • 12. Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
    Yamaguchi H, Bhalla K, Wang HG.
    Cancer Res; 2003 Apr 01; 63(7):1483-9. PubMed ID: 12670894
    [Abstract] [Full Text] [Related]

  • 13. Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways.
    Zhang XD, Gillespie SK, Hersey P.
    Mol Cancer Ther; 2004 Feb 01; 3(2):187-97. PubMed ID: 14985459
    [Abstract] [Full Text] [Related]

  • 14. Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2.
    Adrain C, Creagh EM, Martin SJ.
    EMBO J; 2001 Dec 03; 20(23):6627-36. PubMed ID: 11726499
    [Abstract] [Full Text] [Related]

  • 15. Mitochondrial release of pro-apoptotic proteins: electrostatic interactions can hold cytochrome c but not Smac/DIABLO to mitochondrial membranes.
    Uren RT, Dewson G, Bonzon C, Lithgow T, Newmeyer DD, Kluck RM.
    J Biol Chem; 2005 Jan 21; 280(3):2266-74. PubMed ID: 15537572
    [Abstract] [Full Text] [Related]

  • 16. Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner.
    Guo W, Zhang Y, Ling Z, Liu X, Zhao X, Yuan Z, Nie C, Wei Y.
    Cell Death Dis; 2015 Oct 15; 6(10):e1919. PubMed ID: 26469967
    [Abstract] [Full Text] [Related]

  • 17. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
    Choi S, Singh SV.
    Cancer Res; 2005 Mar 01; 65(5):2035-43. PubMed ID: 15753404
    [Abstract] [Full Text] [Related]

  • 18. Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells.
    Shimizu S, Matsuoka Y, Shinohara Y, Yoneda Y, Tsujimoto Y.
    J Cell Biol; 2001 Jan 22; 152(2):237-50. PubMed ID: 11266442
    [Abstract] [Full Text] [Related]

  • 19. Toxic proteins released from mitochondria in cell death.
    Saelens X, Festjens N, Vande Walle L, van Gurp M, van Loo G, Vandenabeele P.
    Oncogene; 2004 Apr 12; 23(16):2861-74. PubMed ID: 15077149
    [Abstract] [Full Text] [Related]

  • 20. Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis.
    Bidère N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C, Senik A.
    J Biol Chem; 2003 Aug 15; 278(33):31401-11. PubMed ID: 12782632
    [Abstract] [Full Text] [Related]

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