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Journal Abstract Search

279 related items for PubMed ID: 12946641

  • 1. An ultra-HTS process for the identification of small molecule modulators of orphan G-protein-coupled receptors.
    Cacace A, Banks M, Spicer T, Civoli F, Watson J.
    Drug Discov Today; 2003 Sep 01; 8(17):785-92. PubMed ID: 12946641
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  • 2. Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening.
    Eglen RM, Bosse R, Reisine T.
    Assay Drug Dev Technol; 2007 Jun 01; 5(3):425-51. PubMed ID: 17638542
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  • 4. Identification of signal transduction pathways used by orphan g protein-coupled receptors.
    Bresnick JN, Skynner HA, Chapman KL, Jack AD, Zamiara E, Negulescu P, Beaumont K, Patel S, McAllister G.
    Assay Drug Dev Technol; 2003 Apr 01; 1(2):239-49. PubMed ID: 15090189
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  • 6. Identifying ligands at orphan GPCRs: current status using structure-based approaches.
    Ngo T, Kufareva I, Coleman JLj, Graham RM, Abagyan R, Smith NJ.
    Br J Pharmacol; 2016 Oct 01; 173(20):2934-51. PubMed ID: 26837045
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  • 10. The future of G protein-coupled receptors as targets in drug discovery.
    Lundstrom K.
    IDrugs; 2005 Nov 01; 8(11):909-13. PubMed ID: 16254784
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  • 11. High-Throughput Screening for Allosteric Modulators of GPCRs.
    Bertekap RL, Burford NT, Li Z, Alt A.
    Methods Mol Biol; 2015 Nov 01; 1335():223-40. PubMed ID: 26260604
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  • 13. Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers.
    Levoye A, Dam J, Ayoub MA, Guillaume JL, Jockers R.
    EMBO Rep; 2006 Nov 01; 7(11):1094-8. PubMed ID: 17077864
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  • 14. Modeling and Deorphanization of Orphan GPCRs.
    Diaz C, Angelloz-Nicoud P, Pihan E.
    Methods Mol Biol; 2018 Nov 01; 1705():413-429. PubMed ID: 29188576
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  • 18. The CellCard System: a novel approach to assessing compound selectivity for lead prioritization of G protein-coupled receptors.
    Beske O, Goldbard S, Turpin P.
    Comb Chem High Throughput Screen; 2005 Jun 01; 8(4):293-9. PubMed ID: 16101005
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  • 19. Strategies for the identification of allosteric modulators of G-protein-coupled receptors.
    Burford NT, Watson J, Bertekap R, Alt A.
    Biochem Pharmacol; 2011 Mar 15; 81(6):691-702. PubMed ID: 21184747
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