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181 related items for PubMed ID: 12947030

  • 1. Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes.
    Sundgren NC, Giraud GD, Schultz JM, Lasarev MR, Stork PJ, Thornburg KL.
    Am J Physiol Regul Integr Comp Physiol; 2003 Dec; 285(6):R1481-9. PubMed ID: 12947030
    [Abstract] [Full Text] [Related]

  • 2. Unexpected maturation of PI3K and MAPK-ERK signaling in fetal ovine cardiomyocytes.
    Chattergoon NN, Louey S, Stork PJ, Giraud GD, Thornburg KL.
    Am J Physiol Heart Circ Physiol; 2014 Oct 15; 307(8):H1216-25. PubMed ID: 25128174
    [Abstract] [Full Text] [Related]

  • 3. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O, Cantley LC.
    Exp Cell Res; 2004 Jul 01; 297(1):224-34. PubMed ID: 15194438
    [Abstract] [Full Text] [Related]

  • 4. Effects of intrafetal IGF-I on growth of cardiac myocytes in late-gestation fetal sheep.
    Lumbers ER, Kim MY, Burrell JH, Kumarasamy V, Boyce AC, Gibson KJ, Gatford KL, Owens JA.
    Am J Physiol Endocrinol Metab; 2009 Mar 01; 296(3):E513-9. PubMed ID: 19126787
    [Abstract] [Full Text] [Related]

  • 5. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
    Sachdev D, Li SL, Hartell JS, Fujita-Yamaguchi Y, Miller JS, Yee D.
    Cancer Res; 2003 Feb 01; 63(3):627-35. PubMed ID: 12566306
    [Abstract] [Full Text] [Related]

  • 6. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB, Müller FU, Bergmann MW, Li P, Wang Y, Schmitz W, Dietz R, von Harsdorf R.
    Circulation; 2001 Oct 23; 104(17):2088-94. PubMed ID: 11673351
    [Abstract] [Full Text] [Related]

  • 7. Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.
    Sivaprasad U, Fleming J, Verma PS, Hogan KA, Desury G, Cohick WS.
    Endocrinology; 2004 Sep 23; 145(9):4213-21. PubMed ID: 15192040
    [Abstract] [Full Text] [Related]

  • 8. Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1.
    Carrasco L, Cea P, Rocco P, Peña-Oyarzún D, Rivera-Mejias P, Sotomayor-Flores C, Quiroga C, Criollo A, Ibarra C, Chiong M, Lavandero S.
    J Cell Biochem; 2014 Apr 23; 115(4):712-20. PubMed ID: 24243530
    [Abstract] [Full Text] [Related]

  • 9. IGFs stimulate zebrafish cell proliferation by activating MAP kinase and PI3-kinase-signaling pathways.
    Pozios KC, Ding J, Degger B, Upton Z, Duan C.
    Am J Physiol Regul Integr Comp Physiol; 2001 Apr 23; 280(4):R1230-9. PubMed ID: 11247849
    [Abstract] [Full Text] [Related]

  • 10. Thyroid hormone receptor function in maturing ovine cardiomyocytes.
    Chattergoon NN, Louey S, Scanlan T, Lindgren I, Giraud GD, Thornburg KL.
    J Physiol; 2019 Apr 23; 597(8):2163-2176. PubMed ID: 30770568
    [Abstract] [Full Text] [Related]

  • 11. Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes.
    Sundgren NC, Giraud GD, Stork PJ, Maylie JG, Thornburg KL.
    J Physiol; 2003 May 01; 548(Pt 3):881-91. PubMed ID: 12626668
    [Abstract] [Full Text] [Related]

  • 12. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 13. Insulin-like growth factor I-stimulated melanoma cell migration requires phosphoinositide 3-kinase but not extracellular-regulated kinase activation.
    Neudauer CL, McCarthy JB.
    Exp Cell Res; 2003 May 15; 286(1):128-37. PubMed ID: 12729801
    [Abstract] [Full Text] [Related]

  • 14. Systemic arterial hypertension but not IGF-I treatment stimulates cardiomyocyte enlargement in neonatal lambs.
    Wilburn AN, Giraud GD, Louey S, Morgan T, Gandhi N, Jonker SS.
    Am J Physiol Regul Integr Comp Physiol; 2018 Nov 01; 315(5):R1038-R1048. PubMed ID: 30480483
    [Abstract] [Full Text] [Related]

  • 15. IGF-2R-mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep.
    Wang KC, Brooks DA, Botting KJ, Morrison JL.
    Biol Reprod; 2012 Jun 01; 86(6):183. PubMed ID: 22441800
    [Abstract] [Full Text] [Related]

  • 16. Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway.
    McDevitt TC, Laflamme MA, Murry CE.
    J Mol Cell Cardiol; 2005 Dec 01; 39(6):865-73. PubMed ID: 16242146
    [Abstract] [Full Text] [Related]

  • 17. ANG II modulation of cardiac growth and remodeling in immature fetal sheep.
    Sandgren J, Scholz TD, Segar JL.
    Am J Physiol Regul Integr Comp Physiol; 2015 Jun 01; 308(11):R965-72. PubMed ID: 25810382
    [Abstract] [Full Text] [Related]

  • 18. Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.
    Wahyuni T, Kobayashi A, Tanaka S, Miyake Y, Yamamoto A, Bahtiar A, Mori S, Kametani Y, Tomimatsu M, Matsumoto K, Maeda M, Obana M, Fujio Y.
    Am J Physiol Cell Physiol; 2021 Jul 01; 321(1):C82-C93. PubMed ID: 34038245
    [Abstract] [Full Text] [Related]

  • 19. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.
    Diabetes; 2002 Apr 01; 51(4):966-76. PubMed ID: 11916914
    [Abstract] [Full Text] [Related]

  • 20. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
    Kurihara S, Hakuno F, Takahashi S.
    Endocr J; 2000 Dec 01; 47(6):739-51. PubMed ID: 11228049
    [Abstract] [Full Text] [Related]

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