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Journal Abstract Search

278 related items for PubMed ID: 12948016

  • 1. Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells.
    Zhang S, Morris ME.
    Pharm Res; 2003 Aug; 20(8):1184-91. PubMed ID: 12948016
    [Abstract] [Full Text] [Related]

  • 2. Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport.
    Zhang S, Morris ME.
    J Pharmacol Exp Ther; 2003 Mar; 304(3):1258-67. PubMed ID: 12604704
    [Abstract] [Full Text] [Related]

  • 3. Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.
    Shirasaka Y, Kawasaki M, Sakane T, Omatsu H, Moriya Y, Nakamura T, Sakaeda T, Okumura K, Langguth P, Yamashita S.
    Drug Metab Pharmacokinet; 2006 Oct; 21(5):414-23. PubMed ID: 17072095
    [Abstract] [Full Text] [Related]

  • 4. Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
    Troutman MD, Thakker DR.
    Pharm Res; 2003 Aug; 20(8):1200-9. PubMed ID: 12948018
    [Abstract] [Full Text] [Related]

  • 5. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY, Lin SG, Zhou ZW, Chen X, Liang J, Liu PQ, Duan W, Chowbay B, Wen JY, Li CG, Zhou SF.
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells.
    Takanaga H, Ohnishi A, Matsuo H, Sawada Y.
    Biol Pharm Bull; 1998 Oct; 21(10):1062-6. PubMed ID: 9821810
    [Abstract] [Full Text] [Related]

  • 7. Black ginger extract and its active compound, 5,7-dimethoxyflavone, increase intestinal drug absorption via efflux drug transporter inhibitions.
    Boonnop R, Meetam P, Siangjong L, Tuchinda P, Thongphasuk P, Soodvilai S, Soodvilai S.
    Drug Metab Pharmacokinet; 2023 Jun; 50():100500. PubMed ID: 36948091
    [Abstract] [Full Text] [Related]

  • 8. Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
    Tang F, Horie K, Borchardt RT.
    Pharm Res; 2002 Jun; 19(6):765-72. PubMed ID: 12134945
    [Abstract] [Full Text] [Related]

  • 9. Isolation and characterization of Caco-2 subclones expressing high levels of multidrug resistance protein efflux transporter.
    Horie K, Tang F, Borchardt RT.
    Pharm Res; 2003 Feb; 20(2):161-8. PubMed ID: 12636153
    [Abstract] [Full Text] [Related]

  • 10. Grapefruit juice activates P-glycoprotein-mediated drug transport.
    Soldner A, Christians U, Susanto M, Wacher VJ, Silverman JA, Benet LZ.
    Pharm Res; 1999 Apr; 16(4):478-85. PubMed ID: 10227700
    [Abstract] [Full Text] [Related]

  • 11. Transport characteristics of tryptanthrin and its inhibitory effect on P-gp and MRP2 in Caco-2 cells.
    Zhu X, Zhang X, Ma G, Yan J, Wang H, Yang Q.
    J Pharm Pharm Sci; 2011 Apr; 14(3):325-35. PubMed ID: 21824448
    [Abstract] [Full Text] [Related]

  • 12. Ketoconazole and the modulation of multidrug resistance-mediated transport in Caco-2 and MDCKII-MDR1 drug transport models.
    Fan Y, Rodriguez-Proteau R.
    Xenobiotica; 2008 Feb; 38(2):107-29. PubMed ID: 18197554
    [Abstract] [Full Text] [Related]

  • 13. Effect of flavonoids on MRP1-mediated transport in Panc-1 cells.
    Nguyen H, Zhang S, Morris ME.
    J Pharm Sci; 2003 Feb; 92(2):250-7. PubMed ID: 12532374
    [Abstract] [Full Text] [Related]

  • 14. Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells.
    Yoo HH, Lee M, Chung HJ, Lee SK, Kim DH.
    J Agric Food Chem; 2007 Sep 05; 55(18):7620-5. PubMed ID: 17676865
    [Abstract] [Full Text] [Related]

  • 15. Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity.
    Taub ME, Podila L, Ely D, Almeida I.
    Drug Metab Dispos; 2005 Nov 05; 33(11):1679-87. PubMed ID: 16093365
    [Abstract] [Full Text] [Related]

  • 16. Transport and epithelial secretion of the cardiac glycoside, digoxin, by human intestinal epithelial (Caco-2) cells.
    Cavet ME, West M, Simmons NL.
    Br J Pharmacol; 1996 Jul 05; 118(6):1389-96. PubMed ID: 8832062
    [Abstract] [Full Text] [Related]

  • 17. Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.
    Elsby R, Surry DD, Smith VN, Gray AJ.
    Xenobiotica; 2008 Jul 05; 38(7-8):1140-64. PubMed ID: 18668443
    [Abstract] [Full Text] [Related]

  • 18. Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells.
    Makhey VD, Guo A, Norris DA, Hu P, Yan J, Sinko PJ.
    Pharm Res; 1998 Aug 05; 15(8):1160-7. PubMed ID: 9706044
    [Abstract] [Full Text] [Related]

  • 19. Selective inhibition of human cytochrome P450 3A4 by N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-(1, 1-dimethylethylaminocarbonyl)-4-[(furo[2, 3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethy lpentanamide and P-glycoprotein by valspodar in gene transfectant systems.
    Kawahara I, Kato Y, Suzuki H, Achira M, Ito K, Crespi CL, Sugiyama Y.
    Drug Metab Dispos; 2000 Oct 05; 28(10):1238-43. PubMed ID: 10997946
    [Abstract] [Full Text] [Related]

  • 20. Molecular pharmacokinetic mechanism of the drug-drug interaction between genistein and repaglinide mediated by P-gp.
    Jin H, Zhu Y, Wang C, Meng Q, Wu J, Sun P, Ma X, Sun H, Huo X, Liu K, Tan A.
    Biomed Pharmacother; 2020 May 05; 125():110032. PubMed ID: 32187961
    [Abstract] [Full Text] [Related]

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