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Journal Abstract Search

212 related items for PubMed ID: 12948028

  • 1. Pharmacokinetic-pharmacodynamic relationships of (2S,3S)-valnoctamide and its stereoisomer (2R,3S)-valnoctamide in rodent models of epilepsy.
    Isoherranen N, White HS, Klein BD, Roeder M, Woodhead JH, Schurig V, Yagen B, Bialer M.
    Pharm Res; 2003 Aug; 20(8):1293-301. PubMed ID: 12948028
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  • 2. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
    Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M.
    Neuropharmacology; 2010 Jun; 58(8):1228-36. PubMed ID: 20230843
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  • 3. The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Yagen B, Bialer M.
    Epilepsy Behav; 2015 Aug; 49():298-302. PubMed ID: 25979572
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  • 4. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
    Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M.
    Epilepsia; 2014 Feb; 55(2):353-61. PubMed ID: 24313671
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  • 5. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
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  • 6. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
    Epilepsia; 2014 Dec; 55(12):1944-52. PubMed ID: 25442425
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  • 7. Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats.
    Mareš P, Kubová H, Hen N, Yagen B, Bialer M.
    Epilepsy Res; 2013 Sep; 106(1-2):64-73. PubMed ID: 23815889
    [Abstract] [Full Text] [Related]

  • 8. A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
    White HS, Alex AB, Pollock A, Hen N, Shekh-Ahmad T, Wilcox KS, McDonough JH, Stables JP, Kaufmann D, Yagen B, Bialer M.
    Epilepsia; 2012 Jan; 53(1):134-46. PubMed ID: 22150444
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  • 10. Pharmacokinetic and pharmacodynamic analysis of (2S,3S)-sec-butylpropylacetamide (SPD) in rats and pigs-A CNS-active stereoisomer of SPD.
    Bibi D, Bialer M.
    Epilepsia; 2020 Jan; 61(1):149-156. PubMed ID: 31957880
    [Abstract] [Full Text] [Related]

  • 11. Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
    Isoherranen N, Yagen B, Woodhead JH, Spiegelstein O, Blotnik S, Wilcox KS, Finnell RH, Bennett GD, White HS, Bialer M.
    Br J Pharmacol; 2003 Feb; 138(4):602-13. PubMed ID: 12598414
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  • 12. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain.
    Winkler I, Blotnik S, Shimshoni J, Yagen B, Devor M, Bialer M.
    Br J Pharmacol; 2005 Sep; 146(2):198-208. PubMed ID: 15997234
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  • 16. Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice.
    Spiegelstein O, Yagen B, Bennett GD, Finnell RH, Blotnik S, Bialer M.
    Ther Drug Monit; 2000 Oct; 22(5):574-81. PubMed ID: 11034263
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  • 17. Stereoselective pharmacokinetic analysis of valnoctamide in healthy subjects and in patients with epilepsy.
    Barel S, Yagen B, Schurig V, Soback S, Pisani F, Perucca E, Bialer M.
    Clin Pharmacol Ther; 1997 Apr; 61(4):442-9. PubMed ID: 9129561
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  • 19. Pharmacokinetics of a valpromide isomer, valnoctamide, in dogs.
    Haj-Yehia A, Bialer M.
    J Pharm Sci; 1988 Oct; 77(10):831-4. PubMed ID: 3148708
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  • 20. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
    Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsy Behav; 2011 Nov; 22(3):461-8. PubMed ID: 21959082
    [Abstract] [Full Text] [Related]

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