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218 related items for PubMed ID: 12952982

  • 1. PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.
    Mori S, Tanaka M, Nanba D, Nishiwaki E, Ishiguro H, Higashiyama S, Matsuura N.
    J Biol Chem; 2003 Nov 14; 278(46):46029-34. PubMed ID: 12952982
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  • 2. ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands.
    Tanaka M, Nanba D, Mori S, Shiba F, Ishiguro H, Yoshino K, Matsuura N, Higashiyama S.
    J Biol Chem; 2004 Oct 01; 279(40):41950-9. PubMed ID: 15280379
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  • 3. A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
    Izumi Y, Hirata M, Hasuwa H, Iwamoto R, Umata T, Miyado K, Tamai Y, Kurisaki T, Sehara-Fujisawa A, Ohno S, Mekada E.
    EMBO J; 1998 Dec 15; 17(24):7260-72. PubMed ID: 9857183
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  • 4. Phenotypic analysis of Meltrin alpha (ADAM12)-deficient mice: involvement of Meltrin alpha in adipogenesis and myogenesis.
    Kurisaki T, Masuda A, Sudo K, Sakagami J, Higashiyama S, Matsuda Y, Nagabukuro A, Tsuji A, Nabeshima Y, Asano M, Iwakura Y, Sehara-Fujisawa A.
    Mol Cell Biol; 2003 Jan 15; 23(1):55-61. PubMed ID: 12482960
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  • 6. [Membrane-anchored heparin-binding EGF-like growth factor processing by ADAM12 in cardiac hypertrophy].
    Higashiyama S.
    Nihon Rinsho; 2003 May 15; 61(5):767-75. PubMed ID: 12755001
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  • 7. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy.
    Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S.
    Nat Med; 2002 Jan 15; 8(1):35-40. PubMed ID: 11786904
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  • 10. Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
    Sahin U, Weskamp G, Kelly K, Zhou HM, Higashiyama S, Peschon J, Hartmann D, Saftig P, Blobel CP.
    J Cell Biol; 2004 Mar 01; 164(5):769-79. PubMed ID: 14993236
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  • 11. Meltrin alpha cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src.
    Suzuki A, Kadota N, Hara T, Nakagami Y, Izumi T, Takenawa T, Sabe H, Endo T.
    Oncogene; 2000 Nov 30; 19(51):5842-50. PubMed ID: 11127814
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  • 12. A dual signaling cascade that regulates the ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.
    Umata T, Hirata M, Takahashi T, Ryu F, Shida S, Takahashi Y, Tsuneoka M, Miura Y, Masuda M, Horiguchi Y, Mekada E.
    J Biol Chem; 2001 Aug 10; 276(32):30475-82. PubMed ID: 11402047
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  • 13. Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme.
    Nishi E, Hiraoka Y, Yoshida K, Okawa K, Kita T.
    J Biol Chem; 2006 Oct 13; 281(41):31164-72. PubMed ID: 16923819
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  • 18. Ectodomain shedding of membrane-anchored heparin-binding EGF like growth factor and subcellular localization of the C-terminal fragment in the cell cycle.
    Toki F, Nanba D, Matsuura N, Higashiyama S.
    J Cell Physiol; 2005 Mar 13; 202(3):839-48. PubMed ID: 15389565
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  • 19. Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin-binding EGF-like growth factor independently of protein kinase C.
    Dethlefsen SM, Raab G, Moses MA, Adam RM, Klagsbrun M, Freeman MR.
    J Cell Biochem; 1998 May 01; 69(2):143-53. PubMed ID: 9548562
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  • 20. The stress- and inflammatory cytokine-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor is mediated by p38 MAPK, distinct from the 12-O-tetradecanoylphorbol-13-acetate- and lysophosphatidic acid-induced signaling cascades.
    Takenobu H, Yamazaki A, Hirata M, Umata T, Mekada E.
    J Biol Chem; 2003 May 09; 278(19):17255-62. PubMed ID: 12611888
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