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263 related items for PubMed ID: 12960100

  • 1. Parallel phosphatidylinositol-3 kinase and p42/44 mitogen-activated protein kinase signaling pathways subserve the mitogenic and antiapoptotic actions of insulin-like growth factor I in osteoblastic cells.
    Grey A, Chen Q, Xu X, Callon K, Cornish J.
    Endocrinology; 2003 Nov; 144(11):4886-93. PubMed ID: 12960100
    [Abstract] [Full Text] [Related]

  • 2. Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.
    Conejo R, Lorenzo M.
    J Cell Physiol; 2001 Apr; 187(1):96-108. PubMed ID: 11241354
    [Abstract] [Full Text] [Related]

  • 3. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M, Morelli C, Mauro L, Andò S, Surmacz E.
    Cancer Res; 2001 Sep 15; 61(18):6747-54. PubMed ID: 11559546
    [Abstract] [Full Text] [Related]

  • 4. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 15; 45(10):3577-88. PubMed ID: 15452065
    [Abstract] [Full Text] [Related]

  • 5. Lysophosphatidic acid is an osteoblast mitogen whose proliferative actions involve G(i) proteins and protein kinase C, but not P42/44 mitogen-activated protein kinases.
    Grey A, Banovic T, Naot D, Hill B, Callon K, Reid I, Cornish J.
    Endocrinology; 2001 Mar 15; 142(3):1098-106. PubMed ID: 11181524
    [Abstract] [Full Text] [Related]

  • 6. The phospholipids sphingosine-1-phosphate and lysophosphatidic acid prevent apoptosis in osteoblastic cells via a signaling pathway involving G(i) proteins and phosphatidylinositol-3 kinase.
    Grey A, Chen Q, Callon K, Xu X, Reid IR, Cornish J.
    Endocrinology; 2002 Dec 15; 143(12):4755-63. PubMed ID: 12446603
    [Abstract] [Full Text] [Related]

  • 7. Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue.
    Beery R, Haimsohn M, Wertheim N, Hemi R, Nir U, Karasik A, Kanety H, Geier A.
    Endocrinology; 2001 Jul 15; 142(7):3098-107. PubMed ID: 11416032
    [Abstract] [Full Text] [Related]

  • 8. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB, Müller FU, Bergmann MW, Li P, Wang Y, Schmitz W, Dietz R, von Harsdorf R.
    Circulation; 2001 Oct 23; 104(17):2088-94. PubMed ID: 11673351
    [Abstract] [Full Text] [Related]

  • 9. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses.
    Tu Y, Gardner A, Lichtenstein A.
    Cancer Res; 2000 Dec 01; 60(23):6763-70. PubMed ID: 11118064
    [Abstract] [Full Text] [Related]

  • 10. IGF-I elicits growth of human intestinal smooth muscle cells by activation of PI3K, PDK-1, and p70S6 kinase.
    Kuemmerle JF.
    Am J Physiol Gastrointest Liver Physiol; 2003 Mar 01; 284(3):G411-22. PubMed ID: 12444011
    [Abstract] [Full Text] [Related]

  • 11. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
    Chaudhary LR, Hruska KA.
    J Cell Biochem; 2001 Mar 26; 81(2):304-11. PubMed ID: 11241670
    [Abstract] [Full Text] [Related]

  • 12. Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1.
    Cornish J, Grey A, Callon KE, Naot D, Hill BL, Lin CQ, Balchin LM, Reid IR.
    Biochem Biophys Res Commun; 2004 May 21; 318(1):240-6. PubMed ID: 15110779
    [Abstract] [Full Text] [Related]

  • 13. Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein.
    Cheng G, Yu Z, Zhou D, Mattson MP.
    Exp Neurol; 2002 Jun 21; 175(2):407-14. PubMed ID: 12061870
    [Abstract] [Full Text] [Related]

  • 14. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O, Cantley LC.
    Exp Cell Res; 2004 Jul 01; 297(1):224-34. PubMed ID: 15194438
    [Abstract] [Full Text] [Related]

  • 15. Involvement of Raf-1 kinase and protein kinase C zeta in insulin-like growth factor I-induced brown adipocyte mitogenic signaling cascades: inhibition by cyclic adenosine 3',5'-monophosphate.
    Valverde AM, Teruel T, Lorenzo M, Benito M.
    Endocrinology; 1996 Sep 01; 137(9):3832-41. PubMed ID: 8756554
    [Abstract] [Full Text] [Related]

  • 16. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F, Claessens YE, Muller O, Viguié F, Mayeux P, Dreyfus F, Lacombe C, Bouscary D.
    Oncogene; 2002 Sep 26; 21(43):6587-97. PubMed ID: 12242656
    [Abstract] [Full Text] [Related]

  • 17. Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.
    Garrouste F, Remacle-Bonnet M, Fauriat C, Marvaldi J, Luis J, Pommier G.
    Cell Death Differ; 2002 Jul 26; 9(7):768-79. PubMed ID: 12058282
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells.
    Zapf-Colby A, Eichhorn J, Webster NJ, Olefsky JM.
    Oncogene; 1999 Sep 02; 18(35):4908-19. PubMed ID: 10490825
    [Abstract] [Full Text] [Related]

  • 19. Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.
    Sivaprasad U, Fleming J, Verma PS, Hogan KA, Desury G, Cohick WS.
    Endocrinology; 2004 Sep 02; 145(9):4213-21. PubMed ID: 15192040
    [Abstract] [Full Text] [Related]

  • 20. Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).
    Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG, Rhodes CJ.
    J Biol Chem; 2001 Jun 15; 276(24):21110-20. PubMed ID: 11274216
    [Abstract] [Full Text] [Related]

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