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81 related items for PubMed ID: 12963020

  • 1. Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1.
    Yajima H, Suzuki F.
    Biochem Biophys Res Commun; 2003 Sep 26; 309(3):520-7. PubMed ID: 12963020
    [Abstract] [Full Text] [Related]

  • 2. Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation.
    Hu Y, Benedict MA, Wu D, Inohara N, Núñez G.
    Proc Natl Acad Sci U S A; 1998 Apr 14; 95(8):4386-91. PubMed ID: 9539746
    [Abstract] [Full Text] [Related]

  • 3. Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.
    Inohara N, Gourley TS, Carrio R, Muñiz M, Merino J, Garcia I, Koseki T, Hu Y, Chen S, Núñez G.
    J Biol Chem; 1998 Dec 04; 273(49):32479-86. PubMed ID: 9829980
    [Abstract] [Full Text] [Related]

  • 4. Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells.
    Conus S, Rossé T, Borner C.
    Cell Death Differ; 2000 Oct 04; 7(10):947-54. PubMed ID: 11279541
    [Abstract] [Full Text] [Related]

  • 5. The pro-apoptotic function of the C. elegans BCL-2 homolog CED-9 requires interaction with the APAF-1 homolog CED-4.
    Tucker N, Reddien P, Hersh B, Lee D, Liu MHX, Horvitz HR.
    Sci Adv; 2024 Oct 11; 10(41):eadn0325. PubMed ID: 39383227
    [Abstract] [Full Text] [Related]

  • 6. The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4.
    Huang DC, Adams JM, Cory S.
    EMBO J; 1998 Feb 16; 17(4):1029-39. PubMed ID: 9463381
    [Abstract] [Full Text] [Related]

  • 7. Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1.
    Jabbour AM, Puryer MA, Yu JY, Lithgow T, Riffkin CD, Ashley DM, Vaux DL, Ekert PG, Hawkins CJ.
    J Cell Sci; 2006 Jun 15; 119(Pt 12):2572-82. PubMed ID: 16735440
    [Abstract] [Full Text] [Related]

  • 8. Boo, a novel negative regulator of cell death, interacts with Apaf-1.
    Song Q, Kuang Y, Dixit VM, Vincenz C.
    EMBO J; 1999 Jan 04; 18(1):167-78. PubMed ID: 9878060
    [Abstract] [Full Text] [Related]

  • 9. Bcl-XL cooperatively associates with the Bap31 complex in the endoplasmic reticulum, dependent on procaspase-8 and Ced-4 adaptor.
    Ng FW, Shore GC.
    J Biol Chem; 1998 Feb 06; 273(6):3140-3. PubMed ID: 9452422
    [Abstract] [Full Text] [Related]

  • 10. Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.
    Chau BN, Cheng EH, Kerr DA, Hardwick JM.
    Mol Cell; 2000 Jul 06; 6(1):31-40. PubMed ID: 10949025
    [Abstract] [Full Text] [Related]

  • 11. Antiapoptotic Bcl-2 homolog CED-9 in Caenorhabditis elegans: dynamics of BH3 and CED-4 binding regions and comparison with mammalian antiapoptotic Bcl-2 proteins.
    Modi V, Sankararamakrishnan R.
    Proteins; 2014 Jun 06; 82(6):1035-47. PubMed ID: 24218065
    [Abstract] [Full Text] [Related]

  • 12. Bcl-xL does not inhibit the function of Apaf-1.
    Newmeyer DD, Bossy-Wetzel E, Kluck RM, Wolf BB, Beere HM, Green DR.
    Cell Death Differ; 2000 Apr 06; 7(4):402-7. PubMed ID: 10773825
    [Abstract] [Full Text] [Related]

  • 13. "Loop" domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis.
    Fang G, Chang BS, Kim CN, Perkins C, Thompson CB, Bhalla KN.
    Cancer Res; 1998 Aug 01; 58(15):3202-8. PubMed ID: 9699642
    [Abstract] [Full Text] [Related]

  • 14. Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.
    Pourkarimi E, Greiss S, Gartner A.
    Cell Death Differ; 2012 Mar 01; 19(3):406-15. PubMed ID: 21886181
    [Abstract] [Full Text] [Related]

  • 15. Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex.
    Pan G, O'Rourke K, Dixit VM.
    J Biol Chem; 1998 Mar 06; 273(10):5841-5. PubMed ID: 9488720
    [Abstract] [Full Text] [Related]

  • 16. C. elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death.
    Wu D, Chen PJ, Chen S, Hu Y, Nuñez G, Ellis RE.
    Development; 1999 May 06; 126(9):2021-31. PubMed ID: 10101135
    [Abstract] [Full Text] [Related]

  • 17. Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism.
    Contreras V, Friday AJ, Morrison JK, Hao E, Keiper BD.
    PLoS One; 2011 May 06; 6(9):e24444. PubMed ID: 21909434
    [Abstract] [Full Text] [Related]

  • 18. Apoptosome assembly.
    Shi Y.
    Methods Enzymol; 2008 May 06; 442():141-56. PubMed ID: 18662568
    [Abstract] [Full Text] [Related]

  • 19. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.
    Zou H, Henzel WJ, Liu X, Lutschg A, Wang X.
    Cell; 1997 Aug 08; 90(3):405-13. PubMed ID: 9267021
    [Abstract] [Full Text] [Related]

  • 20. The nematode death machine in 3D.
    Pop C, Salvesen GS.
    Cell; 2005 Oct 21; 123(2):192-3. PubMed ID: 16239138
    [Abstract] [Full Text] [Related]

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