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140 related items for PubMed ID: 12963641

  • 1. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment.
    Maack C, Kartes T, Kilter H, Schäfers HJ, Nickenig G, Böhm M, Laufs U.
    Circulation; 2003 Sep 30; 108(13):1567-74. PubMed ID: 12963641
    [Abstract] [Full Text] [Related]

  • 2. Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy.
    Custodis F, Eberl M, Kilter H, Böhm M, Laufs U.
    Cardiovasc Res; 2006 Jul 15; 71(2):342-51. PubMed ID: 16698001
    [Abstract] [Full Text] [Related]

  • 3. Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells.
    Whaley-Connell AT, Morris EM, Rehmer N, Yaghoubian JC, Wei Y, Hayden MR, Habibi J, Stump CS, Sowers JR.
    Am J Nephrol; 2007 Jul 15; 27(1):15-23. PubMed ID: 17204833
    [Abstract] [Full Text] [Related]

  • 4. Rac1 mediates sex difference in cardiac tumor necrosis factor-alpha expression via NADPH oxidase-ERK1/2/p38 MAPK pathway in endotoxemia.
    Zhu H, Shan L, Peng T.
    J Mol Cell Cardiol; 2009 Aug 15; 47(2):264-74. PubMed ID: 19450605
    [Abstract] [Full Text] [Related]

  • 5. Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.
    Antoniades C, Bakogiannis C, Tousoulis D, Reilly S, Zhang MH, Paschalis A, Antonopoulos AS, Demosthenous M, Miliou A, Psarros C, Marinou K, Sfyras N, Economopoulos G, Casadei B, Channon KM, Stefanadis C.
    Circulation; 2010 Sep 14; 122(11 Suppl):S66-73. PubMed ID: 20837928
    [Abstract] [Full Text] [Related]

  • 6. Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart.
    Gupte RS, Vijay V, Marks B, Levine RJ, Sabbah HN, Wolin MS, Recchia FA, Gupte SA.
    J Card Fail; 2007 Aug 14; 13(6):497-506. PubMed ID: 17675065
    [Abstract] [Full Text] [Related]

  • 7. TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.
    Jin S, Ray RM, Johnson LR.
    Am J Physiol Gastrointest Liver Physiol; 2008 Apr 14; 294(4):G928-37. PubMed ID: 18218673
    [Abstract] [Full Text] [Related]

  • 8. Regional heterogeneity of decreased myocardial norepinephrine and increased lipid peroxidation levels in patients with end-stage failing heart secondary to dilated or ischemic cardiomyopathy.
    Rochette L, Tatou E, Vergely C, Maupoil V, Bouchot O, Mossiat C, Jazayeri S, Benkhadra S, Brenot R, Girard C, David M.
    J Heart Lung Transplant; 2008 Jul 14; 27(7):767-74. PubMed ID: 18582807
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction.
    Qin F, Simeone M, Patel R.
    Free Radic Biol Med; 2007 Jul 15; 43(2):271-81. PubMed ID: 17603936
    [Abstract] [Full Text] [Related]

  • 10. Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin.
    Ceolotto G, Papparella I, Lenzini L, Sartori M, Mazzoni M, Iori E, Franco L, Gallo A, de Kreutzenberg SV, Tiengo A, Pessina AC, Avogaro A, Semplicini A.
    Free Radic Biol Med; 2006 Aug 01; 41(3):473-83. PubMed ID: 16843828
    [Abstract] [Full Text] [Related]

  • 11. Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells.
    Nikolova S, Lee YS, Lee YS, Kim JA.
    Free Radic Res; 2005 Dec 01; 39(12):1295-304. PubMed ID: 16298859
    [Abstract] [Full Text] [Related]

  • 12. Expression of nonphagocytic NADPH oxidase system in the ocular lens.
    Rao PV, Maddala R, John F, Zigler JS.
    Mol Vis; 2004 Feb 19; 10():112-21. PubMed ID: 14978478
    [Abstract] [Full Text] [Related]

  • 13. Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism.
    Ito M, Adachi T, Pimentel DR, Ido Y, Colucci WS.
    Circulation; 2004 Jul 27; 110(4):412-8. PubMed ID: 15262848
    [Abstract] [Full Text] [Related]

  • 14. Inhibitory effect of estrogen on Rac1-expression in monocytes.
    Adam O, Hagel M, Theobald K, Böhm M, Laufs U.
    Biochem Biophys Res Commun; 2009 Aug 14; 386(1):45-9. PubMed ID: 19497305
    [Abstract] [Full Text] [Related]

  • 15. Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis.
    Laufs U, Wassmann S, Czech T, Münzel T, Eisenhauer M, Böhm M, Nickenig G.
    Arterioscler Thromb Vasc Biol; 2005 Apr 14; 25(4):809-14. PubMed ID: 15692095
    [Abstract] [Full Text] [Related]

  • 16. ACE2 gene expression is up-regulated in the human failing heart.
    Goulter AB, Goddard MJ, Allen JC, Clark KL.
    BMC Med; 2004 May 19; 2():19. PubMed ID: 15151696
    [Abstract] [Full Text] [Related]

  • 17. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
    Niu J, Profirovic J, Pan H, Vaiskunaite R, Voyno-Yasenetskaya T.
    Circ Res; 2003 Oct 31; 93(9):848-56. PubMed ID: 14512443
    [Abstract] [Full Text] [Related]

  • 18. Glycated proteins stimulate reactive oxygen species production in cardiac myocytes: involvement of Nox2 (gp91phox)-containing NADPH oxidase.
    Zhang M, Kho AL, Anilkumar N, Chibber R, Pagano PJ, Shah AM, Cave AC.
    Circulation; 2006 Mar 07; 113(9):1235-43. PubMed ID: 16505175
    [Abstract] [Full Text] [Related]

  • 19. NADPH oxidase-dependent redox signaling in human heart failure: relationship between the left and right ventricle.
    Nediani C, Borchi E, Giordano C, Baruzzo S, Ponziani V, Sebastiani M, Nassi P, Mugelli A, d'Amati G, Cerbai E.
    J Mol Cell Cardiol; 2007 Apr 07; 42(4):826-34. PubMed ID: 17346742
    [Abstract] [Full Text] [Related]

  • 20. Rac1 inhibition protects against hypoxia/reoxygenation-induced lipid peroxidation in human vascular endothelial cells.
    Martin SF, Chatterjee S, Parinandi N, Alevriadou BR.
    Vascul Pharmacol; 2005 Sep 07; 43(3):148-56. PubMed ID: 16099726
    [Abstract] [Full Text] [Related]

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