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Journal Abstract Search

740 related items for PubMed ID: 12964030

  • 1. TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.
    Pasanen T, Hakkarainen T, Timonen P, Parkkinen J, Tenhunen A, Loimas S, Wahlfors J.
    Int J Mol Med; 2003 Oct; 12(4):525-31. PubMed ID: 12964030
    [Abstract] [Full Text] [Related]

  • 2. VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct.
    Hakkarainen T, Wahlfors T, Meriläinen O, Loimas S, Hemminki A, Wahlfors J.
    J Gene Med; 2005 Jul; 7(7):898-907. PubMed ID: 15759279
    [Abstract] [Full Text] [Related]

  • 3. In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.
    Okada T, Caplen NJ, Ramsey WJ, Onodera M, Shimazaki K, Nomoto T, Ajalli R, Wildner O, Morris J, Kume A, Hamada H, Blaese RM, Ozawa K.
    J Gene Med; 2004 Mar; 6(3):288-99. PubMed ID: 15026990
    [Abstract] [Full Text] [Related]

  • 4. Retrovirus-mediated gene therapy of experimental brain neoplasms using the herpes simplex virus-thymidine kinase/ganciclovir paradigm.
    Rainov NG, Kramm CM, Aboody-Guterman K, Chase M, Ueki K, Louis DN, Harsh GR, Chiocca A, Breakefield XO.
    Cancer Gene Ther; 1996 Mar; 3(2):99-106. PubMed ID: 8729908
    [Abstract] [Full Text] [Related]

  • 5. HIV-1 TAT protein transduction domain mediates enhancement of enzyme prodrug cancer gene therapy in vitro: a study with TAT-TK-GFP triple fusion construct.
    Meriläinen O, Hakkarainen T, Wahlfors T, Pellinen R, Wahlfors J.
    Int J Oncol; 2005 Jul; 27(1):203-8. PubMed ID: 15942661
    [Abstract] [Full Text] [Related]

  • 6. Non-small cell lung cancer as a target disease for herpes simplex type 1 thymidine kinase-ganciclovir gene therapy.
    Määttä AM, Tenhunen A, Pasanen T, Meriläinen O, Pellinen R, Mäkinen K, Alhava E, Wahlfors J.
    Int J Oncol; 2004 Apr; 24(4):943-9. PubMed ID: 15010834
    [Abstract] [Full Text] [Related]

  • 7. Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.
    Yang L, Hwang R, Chiang Y, Gordon EM, Anderson WF, Parekh D.
    Clin Cancer Res; 1998 Mar; 4(3):731-41. PubMed ID: 9533543
    [Abstract] [Full Text] [Related]

  • 8. HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma.
    Moriuchi S, Krisky DM, Marconi PC, Tamura M, Shimizu K, Yoshimine T, Cohen JB, Glorioso JC.
    Gene Ther; 2000 Sep; 7(17):1483-90. PubMed ID: 11001368
    [Abstract] [Full Text] [Related]

  • 9. Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir.
    Howard BD, Boenicke L, Schniewind B, Henne-Bruns D, Kalthoff H.
    Cancer Gene Ther; 2000 Jun; 7(6):927-38. PubMed ID: 10880025
    [Abstract] [Full Text] [Related]

  • 10. Differential cytotoxicity and bystander effect of the rabbit cytochrome P450 4B1 enzyme gene by two different prodrugs: implications for pharmacogene therapy.
    Frank S, Steffens S, Fischer U, Tlolko A, Rainov NG, Kramm CM.
    Cancer Gene Ther; 2002 Feb; 9(2):178-88. PubMed ID: 11857036
    [Abstract] [Full Text] [Related]

  • 11. BCR-ABL-expressing cells transduced with the HSV-tk gene die by apoptosis upon treatment with ganciclovir.
    Rivas C, Miller AR, Collado M, Lam EW, Apperley JF, Melo JV.
    Mol Ther; 2001 May; 3(5 Pt 1):642-52. PubMed ID: 11356068
    [Abstract] [Full Text] [Related]

  • 12. HSV-tk gene therapy for human renal cell carcinoma in nude mice.
    Pulkkanen KJ, Parkkinen JJ, Laukkanen JM, Kettunen MI, Tyynela K, Kauppinen RA, Ala-Opas MY, Yla-Herttuala S.
    Cancer Gene Ther; 2001 Jul; 8(7):529-36. PubMed ID: 11498775
    [Abstract] [Full Text] [Related]

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  • 14. Evaluation of herpes simplex thymidine kinase mediated gene therapy in experimental pancreatic cancer.
    Mäkinen K, Loimas S, Wahlfors J, Alhava E, Jänne J.
    J Gene Med; 2000 Jul; 2(5):361-7. PubMed ID: 11045430
    [Abstract] [Full Text] [Related]

  • 15. Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirus.
    Raki M, Hakkarainen T, Bauerschmitz GJ, Särkioja M, Desmond RA, Kanerva A, Hemminki A.
    Gene Ther; 2007 Oct; 14(19):1380-8. PubMed ID: 17611584
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  • 18. Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions.
    Sandmair AM, Turunen M, Tyynelä K, Loimas S, Vainio P, Vanninen R, Vapalahti M, Bjerkvig R, Jänne J, Ylä-Herttuala S.
    Cancer Gene Ther; 2000 Mar; 7(3):413-21. PubMed ID: 10766347
    [Abstract] [Full Text] [Related]

  • 19. Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene.
    Esandi MC, van Someren GD, Vincent AJ, van Bekkum DW, Valerio D, Bout A, Noteboom JL.
    Gene Ther; 1997 Apr; 4(4):280-7. PubMed ID: 9176512
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