These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Analysis of catalytic carboxylate mutants E552Q and E1197Q suggests asymmetric ATP hydrolysis by the two nucleotide-binding domains of P-glycoprotein. Carrier I, Julien M, Gros P. Biochemistry; 2003 Nov 11; 42(44):12875-85. PubMed ID: 14596601 [Abstract] [Full Text] [Related]
5. Mutational analysis of conserved aromatic residues in the A-loop of the ABC transporter ABCB1A (mouse Mdr3). Carrier I, Urbatsch IL, Senior AE, Gros P. FEBS Lett; 2007 Jan 23; 581(2):301-8. PubMed ID: 17214987 [Abstract] [Full Text] [Related]
6. Importance of the conserved Walker B glutamate residues, 556 and 1201, for the completion of the catalytic cycle of ATP hydrolysis by human P-glycoprotein (ABCB1). Sauna ZE, Müller M, Peng XH, Ambudkar SV. Biochemistry; 2002 Nov 26; 41(47):13989-4000. PubMed ID: 12437356 [Abstract] [Full Text] [Related]
7. Purification and characterization of the N-terminal nucleotide binding domain of an ABC drug transporter of Candida albicans: uncommon cysteine 193 of Walker A is critical for ATP hydrolysis. Jha S, Karnani N, Dhar SK, Mukhopadhayay K, Shukla S, Saini P, Mukhopadhayay G, Prasad R. Biochemistry; 2003 Sep 16; 42(36):10822-32. PubMed ID: 12962507 [Abstract] [Full Text] [Related]
11. Functional characterization of N-terminal nucleotide binding domain (NBD-1) of a major ABC drug transporter Cdr1p of Candida albicans: uncommon but conserved Trp326 of Walker B is important for ATP binding. Rai V, Shukla S, Jha S, Komath SS, Prasad R. Biochemistry; 2005 May 03; 44(17):6650-61. PubMed ID: 15850398 [Abstract] [Full Text] [Related]
12. Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK. Schmees G, Stein A, Hunke S, Landmesser H, Schneider E. Eur J Biochem; 1999 Dec 03; 266(2):420-30. PubMed ID: 10561582 [Abstract] [Full Text] [Related]
13. Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). Payen LF, Gao M, Westlake CJ, Cole SP, Deeley RG. J Biol Chem; 2003 Oct 03; 278(40):38537-47. PubMed ID: 12882957 [Abstract] [Full Text] [Related]
16. Combined mutation of catalytic glutamate residues in the two nucleotide binding domains of P-glycoprotein generates a conformation that binds ATP and ADP tightly. Tombline G, Bartholomew LA, Urbatsch IL, Senior AE. J Biol Chem; 2004 Jul 23; 279(30):31212-20. PubMed ID: 15159388 [Abstract] [Full Text] [Related]
17. Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites. Urbatsch IL, Beaudet L, Carrier I, Gros P. Biochemistry; 1998 Mar 31; 37(13):4592-602. PubMed ID: 9521779 [Abstract] [Full Text] [Related]