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485 related items for PubMed ID: 12971801
1. Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid. Chou MW, Jian Y, Williams LD, Xia Q, Churchwell M, Doerge DR, Fu PP. Chem Res Toxicol; 2003 Sep; 16(9):1130-7. PubMed ID: 12971801 [Abstract] [Full Text] [Related]
2. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Wang YP, Yan J, Fu PP, Chou MW. Toxicol Lett; 2005 Mar 15; 155(3):411-20. PubMed ID: 15649625 [Abstract] [Full Text] [Related]
3. High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of pyrrolizidine alkaloid-derived DNA adducts in vitro and in vivo. Fu PP, Chou MW, Churchwell M, Wang Y, Zhao Y, Xia Q, Gamboa da Costa G, Marques MM, Beland FA, Doerge DR. Chem Res Toxicol; 2010 Mar 15; 23(3):637-52. PubMed ID: 20078085 [Abstract] [Full Text] [Related]
4. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine. Xia Q, Yan J, Chou MW, Fu PP. Toxicol Lett; 2008 May 05; 178(2):77-82. PubMed ID: 18395999 [Abstract] [Full Text] [Related]
5. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts. Yan J, Xia Q, Chou MW, Fu PP. Toxicol Ind Health; 2008 Apr 05; 24(3):181-8. PubMed ID: 18842697 [Abstract] [Full Text] [Related]
11. Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine. Chou MW, Wang YP, Yan J, Yang YC, Beger RD, Williams LD, Doerge DR, Fu PP. Toxicol Lett; 2003 Dec 10; 145(3):239-47. PubMed ID: 14580895 [Abstract] [Full Text] [Related]
12. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, retrorsine, leading to DNA adduct formation in vivo. Wang YP, Fu PP, Chou MW. Int J Environ Res Public Health; 2005 Apr 10; 2(1):74-9. PubMed ID: 16705803 [Abstract] [Full Text] [Related]
13. 7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids. He X, Xia Q, Ma L, Fu PP. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2016 Apr 10; 34(1):57-76. PubMed ID: 26761716 [Abstract] [Full Text] [Related]
14. Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo. Yang YC, Yan J, Doerge DR, Chan PC, Fu PP, Chou MW. Chem Res Toxicol; 2001 Jan 10; 14(1):101-9. PubMed ID: 11170513 [Abstract] [Full Text] [Related]
15. Quantification of tamoxifen DNA adducts using on-line sample preparation and HPLC-electrospray ionization tandem mass spectrometry. Gamboa da Costa G, Marques MM, Beland FA, Freeman JP, Churchwell MI, Doerge DR. Chem Res Toxicol; 2003 Mar 10; 16(3):357-66. PubMed ID: 12641436 [Abstract] [Full Text] [Related]
16. Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation. Xia Q, He X, Ma L, Chen S, Fu PP. Chem Res Toxicol; 2018 Jul 16; 31(7):619-628. PubMed ID: 29855181 [Abstract] [Full Text] [Related]