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Journal Abstract Search

241 related items for PubMed ID: 12974624

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  • 5. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.
    Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA.
    J Biol Chem; 2004 Apr 23; 279(17):18034-45. PubMed ID: 14966129
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  • 7. Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis.
    Wall M, Shim JH, Benkovic SJ.
    Biochemistry; 2000 Sep 19; 39(37):11303-11. PubMed ID: 10985775
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  • 8. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
    Greasley SE, Horton P, Ramcharan J, Beardsley GP, Benkovic SJ, Wilson IA.
    Nat Struct Biol; 2001 May 19; 8(5):402-6. PubMed ID: 11323713
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  • 9. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
    Li C, Xu L, Wolan DW, Wilson IA, Olson AJ.
    J Med Chem; 2004 Dec 30; 47(27):6681-90. PubMed ID: 15615517
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  • 11. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis.
    Verma P, Kar B, Varshney R, Roy P, Sharma AK.
    FEBS J; 2017 Dec 30; 284(24):4233-4261. PubMed ID: 29063699
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  • 14. Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase.
    Vergis JM, Beardsley GP.
    Biochemistry; 2004 Feb 10; 43(5):1184-92. PubMed ID: 14756554
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  • 16. AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans.
    Wizrah MSI, Chua SMH, Luo Z, Manik MK, Pan M, Whyte JML, Robertson AAB, Kappler U, Kobe B, Fraser JA.
    J Biol Chem; 2022 Oct 10; 298(10):102453. PubMed ID: 36063996
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  • 17. Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution.
    Klein C, Chen P, Arevalo JH, Stura EA, Marolewski A, Warren MS, Benkovic SJ, Wilson IA.
    J Mol Biol; 1995 May 26; 249(1):153-75. PubMed ID: 7776369
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  • 18. 10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.
    Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL.
    Bioorg Med Chem; 2003 Oct 01; 11(20):4503-9. PubMed ID: 13129586
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  • 19. The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling.
    Bulock KG, Beardsley GP, Anderson KS.
    J Biol Chem; 2002 Jun 21; 277(25):22168-74. PubMed ID: 11948179
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  • 20. Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase.
    Greasley SE, Marsilje TH, Cai H, Baker S, Benkovic SJ, Boger DL, Wilson IA.
    Biochemistry; 2001 Nov 13; 40(45):13538-47. PubMed ID: 11695901
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