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865 related items for PubMed ID: 12975249

  • 1. Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts.
    Xiao RP, Zhang SJ, Chakir K, Avdonin P, Zhu W, Bond RA, Balke CW, Lakatta EG, Cheng H.
    Circulation; 2003 Sep 30; 108(13):1633-9. PubMed ID: 12975249
    [Abstract] [Full Text] [Related]

  • 2. Enhanced cardiac L-type calcium current response to beta2-adrenergic stimulation in heart failure.
    Zhang ZS, Cheng HJ, Ukai T, Tachibana H, Cheng CP.
    J Pharmacol Exp Ther; 2001 Jul 30; 298(1):188-96. PubMed ID: 11408541
    [Abstract] [Full Text] [Related]

  • 3. Developmental changes in beta2-adrenergic receptor signaling in ventricular myocytes: the role of Gi proteins and caveolae microdomains.
    Rybin VO, Pak E, Alcott S, Steinberg SF.
    Mol Pharmacol; 2003 Jun 30; 63(6):1338-48. PubMed ID: 12761344
    [Abstract] [Full Text] [Related]

  • 4. Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins.
    Xiao RP.
    Sci STKE; 2001 Oct 16; 2001(104):re15. PubMed ID: 11604549
    [Abstract] [Full Text] [Related]

  • 5. Temporal dynamics of inotropic, chronotropic, and metabolic responses during beta1- and beta2-AR stimulation in the isolated, perfused rat heart.
    McConville P, Spencer RG, Lakatta EG.
    Am J Physiol Endocrinol Metab; 2005 Sep 16; 289(3):E412-8. PubMed ID: 15840637
    [Abstract] [Full Text] [Related]

  • 6. Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
    Duarte T, Menezes-Rodrigues FS, Godinho RO.
    J Pharmacol Exp Ther; 2012 Jun 16; 341(3):820-8. PubMed ID: 22438472
    [Abstract] [Full Text] [Related]

  • 7. Agonist-specific activation of the beta2-adrenoceptor/Gs-protein and beta2-adrenoceptor/Gi-protein pathway in adult rat ventricular cardiomyocytes.
    Pönicke K, Gröner F, Heinroth-Hoffmann I, Brodde OE.
    Br J Pharmacol; 2006 Apr 16; 147(7):714-9. PubMed ID: 16474418
    [Abstract] [Full Text] [Related]

  • 8. Enhanced inhibition of L-type Ca2+ current by beta3-adrenergic stimulation in failing rat heart.
    Zhang ZS, Cheng HJ, Onishi K, Ohte N, Wannenburg T, Cheng CP.
    J Pharmacol Exp Ther; 2005 Dec 16; 315(3):1203-11. PubMed ID: 16135702
    [Abstract] [Full Text] [Related]

  • 9. Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases.
    Xiao RP, Tomhave ED, Wang DJ, Ji X, Boluyt MO, Cheng H, Lakatta EG, Koch WJ.
    J Clin Invest; 1998 Mar 15; 101(6):1273-82. PubMed ID: 9502768
    [Abstract] [Full Text] [Related]

  • 10. G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels.
    Chen-Izu Y, Xiao RP, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG.
    Biophys J; 2000 Nov 15; 79(5):2547-56. PubMed ID: 11053129
    [Abstract] [Full Text] [Related]

  • 11. Disruption of inhibitory G-proteins mediates a reduction in atrial beta-adrenergic signaling by enhancing eNOS expression.
    Danson EJ, Zhang YH, Sears CE, Edwards AR, Casadei B, Paterson DJ.
    Cardiovasc Res; 2005 Sep 01; 67(4):613-23. PubMed ID: 15936740
    [Abstract] [Full Text] [Related]

  • 12. Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching beta1-adrenergic but locally confined beta2-adrenergic receptor-mediated signaling.
    Nikolaev VO, Bünemann M, Schmitteckert E, Lohse MJ, Engelhardt S.
    Circ Res; 2006 Nov 10; 99(10):1084-91. PubMed ID: 17038640
    [Abstract] [Full Text] [Related]

  • 13. Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
    Leblais V, Jo SH, Chakir K, Maltsev V, Zheng M, Crow MT, Wang W, Lakatta EG, Xiao RP.
    Circ Res; 2004 Dec 10; 95(12):1183-90. PubMed ID: 15539636
    [Abstract] [Full Text] [Related]

  • 14. Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice.
    Devic E, Xiang Y, Gould D, Kobilka B.
    Mol Pharmacol; 2001 Sep 10; 60(3):577-83. PubMed ID: 11502890
    [Abstract] [Full Text] [Related]

  • 15. Divergent agonist selectivity in activating β1- and β2-adrenoceptors for G-protein and arrestin coupling.
    Casella I, Ambrosio C, Grò MC, Molinari P, Costa T.
    Biochem J; 2011 Aug 15; 438(1):191-202. PubMed ID: 21561432
    [Abstract] [Full Text] [Related]

  • 16. Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
    Kassner A, Toischer K, Bohms B, Kolkhof P, Abraham G, Hasenfuβ G, Morshuis M, Schulte Eistrup S, El-Banayosy A, Gummert J, Milting H.
    J Heart Lung Transplant; 2012 Oct 15; 31(10):1127-35. PubMed ID: 22975104
    [Abstract] [Full Text] [Related]

  • 17. Myocyte nitric oxide synthase 2 contributes to blunted beta-adrenergic response in failing human hearts by decreasing Ca2+ transients.
    Ziolo MT, Maier LS, Piacentino V, Bossuyt J, Houser SR, Bers DM.
    Circulation; 2004 Apr 20; 109(15):1886-91. PubMed ID: 15037528
    [Abstract] [Full Text] [Related]

  • 18. Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes.
    Xiao RP, Ji X, Lakatta EG.
    Mol Pharmacol; 1995 Feb 20; 47(2):322-9. PubMed ID: 7870040
    [Abstract] [Full Text] [Related]

  • 19. Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy.
    Ahmet I, Krawczyk M, Heller P, Moon C, Lakatta EG, Talan MI.
    Circulation; 2004 Aug 31; 110(9):1083-90. PubMed ID: 15313944
    [Abstract] [Full Text] [Related]

  • 20. Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.
    Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP.
    Circ Res; 2005 Aug 05; 97(3):244-51. PubMed ID: 16002745
    [Abstract] [Full Text] [Related]

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