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126 related items for PubMed ID: 1312170

  • 1. Dopaminergic neurotoxicity of 1-methyl-4-phenylpyridinium analogs in cultured neurons: relationship to the dopamine uptake system and inhibition of mitochondrial respiration.
    Saporito MS, Heikkila RE, Youngster SK, Nicklas WJ, Geller HM.
    J Pharmacol Exp Ther; 1992 Mar; 260(3):1400-9. PubMed ID: 1312170
    [Abstract] [Full Text] [Related]

  • 2. Toxic effects of potential environmental neurotoxins related to 1-methyl-4-phenylpyridinium on cultured rat dopaminergic neurons.
    Michel PP, Dandapani BK, Sanchez-Ramos J, Efange S, Pressman BC, Hefti F.
    J Pharmacol Exp Ther; 1989 Feb; 248(2):842-50. PubMed ID: 2783974
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds.
    Sablin SO, Krueger MJ, Yankovskaya VL, Tkachenko SE, Razdolsky AN, Bachurin SO, Ramsay RR, Singer TP.
    J Biochem Toxicol; 1996 Feb; 11(1):33-43. PubMed ID: 8806050
    [Abstract] [Full Text] [Related]

  • 4. Dopaminergic neurotoxicity by 6-OHDA and MPP+: differential requirement for neuronal cyclooxygenase activity.
    Carrasco E, Casper D, Werner P.
    J Neurosci Res; 2005 Jul 01; 81(1):121-31. PubMed ID: 15931668
    [Abstract] [Full Text] [Related]

  • 5. Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-L-carnitine.
    Virmani A, Gaetani F, Binienda Z, Xu A, Duhart H, Ali SF.
    Ann N Y Acad Sci; 2004 Oct 01; 1025():267-73. PubMed ID: 15542726
    [Abstract] [Full Text] [Related]

  • 6. Effects of enhancing mitochondrial oxidative phosphorylation with reducing equivalents and ubiquinone on 1-methyl-4-phenylpyridinium toxicity and complex I-IV damage in neuroblastoma cells.
    Mazzio EA, Soliman KF.
    Biochem Pharmacol; 2004 Mar 15; 67(6):1167-84. PubMed ID: 15006552
    [Abstract] [Full Text] [Related]

  • 7. Methylphenylpyridium ion (MPP+) enhances glutamate-induced cytotoxicity against dopaminergic neurons in cultured rat mesencephalon.
    Sawada H, Shimohama S, Tamura Y, Kawamura T, Akaike A, Kimura J.
    J Neurosci Res; 1996 Jan 01; 43(1):55-62. PubMed ID: 8838574
    [Abstract] [Full Text] [Related]

  • 8. 1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies.
    Bloomquist J, King E, Wright A, Mytilineou C, Kimura K, Castagnoli K, Castagnoli N.
    J Pharmacol Exp Ther; 1994 Aug 01; 270(2):822-30. PubMed ID: 8071874
    [Abstract] [Full Text] [Related]

  • 9. MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.
    Rollema H, Skolnik M, D'Engelbronner J, Igarashi K, Usuki E, Castagnoli N.
    J Pharmacol Exp Ther; 1994 Jan 01; 268(1):380-7. PubMed ID: 8301579
    [Abstract] [Full Text] [Related]

  • 10. Catecholamine transporters and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity: studies comparing the cloned human noradrenaline and human dopamine transporter.
    Pifl C, Hornykiewicz O, Giros B, Caron MG.
    J Pharmacol Exp Ther; 1996 Jun 01; 277(3):1437-43. PubMed ID: 8667208
    [Abstract] [Full Text] [Related]

  • 11. Structure-neurotoxicity trends of analogues of 1-methyl-4-phenylpyridinium (MPP+), the cytotoxic metabolite of the dopaminergic neurotoxin MPTP.
    Arora PK, Riachi NJ, Fiedler GC, Singh MP, Abdallah F, Harik SI, Sayre LM.
    Life Sci; 1990 Jun 01; 46(5):379-90. PubMed ID: 2304377
    [Abstract] [Full Text] [Related]

  • 12. The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.
    Nakamura K, Bindokas VP, Marks JD, Wright DA, Frim DM, Miller RJ, Kang UJ.
    Mol Pharmacol; 2000 Aug 01; 58(2):271-8. PubMed ID: 10908294
    [Abstract] [Full Text] [Related]

  • 13. Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.
    Villarán RF, Tomás-Camardiel M, de Pablos RM, Santiago M, Herrera AJ, Navarro A, Machado A, Cano J.
    Neurotoxicology; 2008 Mar 01; 29(2):244-58. PubMed ID: 18093658
    [Abstract] [Full Text] [Related]

  • 14. 1-methyl-4-phenylpyridinium (MPP+) analogs: in vivo neurotoxicity and inhibition of striatal synaptosomal dopamine uptake.
    Johnson EA, Wu EY, Rollema H, Booth RG, Trevor AJ, Castagnoli N.
    Eur J Pharmacol; 1989 Jul 04; 166(1):65-74. PubMed ID: 2806366
    [Abstract] [Full Text] [Related]

  • 15. Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells.
    Wang J, Duhart HM, Xu Z, Patterson TA, Newport GD, Ali SF.
    Neurochem Int; 2008 May 04; 52(6):1037-43. PubMed ID: 18069091
    [Abstract] [Full Text] [Related]

  • 16. MPP(+)-induced mitochondrial dysfunction is potentiated by dopamine.
    Boada J, Cutillas B, Roig T, Bermúdez J, Ambrosio S.
    Biochem Biophys Res Commun; 2000 Feb 24; 268(3):916-20. PubMed ID: 10679305
    [Abstract] [Full Text] [Related]

  • 17. Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture.
    Michel PP, Hefti F.
    J Neurosci Res; 1990 Aug 24; 26(4):428-35. PubMed ID: 1977925
    [Abstract] [Full Text] [Related]

  • 18. Lack of involvement of glutamate-induced excitotoxicity in MPP+ toxicity in striatal dopaminergic terminals: possible involvement of ascorbate.
    Matarredona ER, Santiago M, Machado A, Cano J.
    Br J Pharmacol; 1997 Jul 24; 121(5):1038-44. PubMed ID: 9222565
    [Abstract] [Full Text] [Related]

  • 19. Interleukin-1 beta enhances survival and interleukin-6 protects against MPP+ neurotoxicity in cultures of fetal rat dopaminergic neurons.
    Akaneya Y, Takahashi M, Hatanaka H.
    Exp Neurol; 1995 Nov 24; 136(1):44-52. PubMed ID: 7589333
    [Abstract] [Full Text] [Related]

  • 20. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.
    Youngster SK, Nicklas WJ, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun 24; 249(3):829-35. PubMed ID: 2786565
    [Abstract] [Full Text] [Related]

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