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Journal Abstract Search

197 related items for PubMed ID: 1319166

  • 1. Further SAR in the new antitumor 1-amino-substituted gamma-carbolines and 5H-benzo[e]pyrido[4,3-b]indoles series.
    Nguyen CH, Lavelle F, Riou JF, Bissery MC, Huel C, Bisagni E.
    Anticancer Drug Des; 1992 Jun; 7(3):235-51. PubMed ID: 1319166
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  • 2. Synthesis and antitumor properties of new 4-methyl-substituted- pyrido[4,3-b]indoles (gamma-carbolines).
    Nguyen CH, Bisagni E, Lavelle F, Bissery MC, Huel C.
    Anticancer Drug Des; 1992 Jun; 7(3):219-33. PubMed ID: 1610481
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  • 3. Intoplicine (RP 60475) and its derivatives, a new class of antitumor agents inhibiting both topoisomerase I and II activities.
    Riou JF, Fossé P, Nguyen CH, Larsen AK, Bissery MC, Grondard L, Saucier JM, Bisagni E, Lavelle F.
    Cancer Res; 1993 Dec 15; 53(24):5987-93. PubMed ID: 8261412
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  • 4. Synthesis, properties and biological evaluation of substituted furo[3,2-e] and pyrano[3,2-e]pyrido[4,3-b]indoles.
    Costache E, Nguyen CH, Guilbaud N, Léonce S, Pierré A, Atassi G, Bisagni E.
    Anticancer Drug Des; 1998 Jun 15; 13(4):373-86. PubMed ID: 9627674
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  • 5. Synthesis and biological evaluation of amino-substituted benzo[f]pyrido[4,3-b] and pyrido[3,4-b]quinoxalines: a new class of antineoplastic agents.
    Nguyen CH, Fan E, Riou JF, Bissery MC, Vrignaud P, Lavelle F, Bisagni E.
    Anticancer Drug Des; 1995 Jun 15; 10(4):277-97. PubMed ID: 7786395
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  • 7. 1-Amino-substituted 8-hydroxy-4,5-dimethyl-5H-pyrido[4,3-b]indoles with propyl- or methyl substituents at the 9-, and 7,9-positions: synthesis and biological evaluation.
    Costache E, Nguyen CH, Léonce S, Pierré A, Atassi G, Bisagni E.
    Anticancer Drug Des; 1998 Jun 15; 13(4):361-72. PubMed ID: 9627673
    [Abstract] [Full Text] [Related]

  • 8. Synthesis of 9-O-substituted derivatives of 9-hydroxy-5, 6-dimethyl-6H-pyrido[4,3-b]carbazole-1-carboxylic acid (2-(dimethylamino)ethyl)amide and their 10- and 11-methyl analogues with improved antitumor activity.
    Guillonneau C, PierréA, Charton Y, Guilbaud N, Kraus-Berthier L, Léonce S, Michel A, Bisagni E, Atassi G.
    J Med Chem; 1999 Jun 17; 42(12):2191-203. PubMed ID: 10377224
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  • 10. Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents.
    Nguyen CH, Lhoste JM, Lavelle F, Bissery MC, Bisagni E.
    J Med Chem; 1990 May 17; 33(5):1519-28. PubMed ID: 2329575
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  • 14. Antitumor agents. 5. synthesis, structure-activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5h-benzopyridophenoxazin-5-ones, and 5h-benzopyridophenoxazin-5-ones with potent antiproliferative activity.
    Bolognese A, Correale G, Manfra M, Lavecchia A, Novellino E, Pepe S.
    J Med Chem; 2006 Aug 24; 49(17):5110-8. PubMed ID: 16913700
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  • 17. Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Perni RB, Wentland MP, Huang JI, Powles RG, Aldous S, Klingbeil KM, Peverly AD, Robinson RG, Corbett TH, Jones JL, Mattes KC, Rake JB, Coughlin SA.
    J Med Chem; 1998 Sep 10; 41(19):3645-54. PubMed ID: 9733489
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  • 18. Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders.
    Lim J, Taoka B, Otte RD, Spencer K, Dinsmore CJ, Altman MD, Chan G, Rosenstein C, Sharma S, Su HP, Szewczak AA, Xu L, Yin H, Zugay-Murphy J, Marshall CG, Young JR.
    J Med Chem; 2011 Oct 27; 54(20):7334-49. PubMed ID: 21942426
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  • 19. 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) triggers apoptosis by DNA double-strand breaks caused by inhibition of topoisomerase I.
    Shiotani B, Ashida H.
    Carcinogenesis; 2004 Jul 27; 25(7):1149-55. PubMed ID: 14976128
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  • 20. Catalysis of the covalent binding of 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole to DNA by a L-proline- and adenosine triphosphate-dependent enzyme in rat hepatic cytosol.
    Yamazoe Y, Shimada M, Shinohara A, Saito K, Kamataki T, Kato R.
    Cancer Res; 1985 Jun 27; 45(6):2495-500. PubMed ID: 3986789
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