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184 related items for PubMed ID: 1323203

  • 1. Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines.
    Freisheim JH, Ratnam M, McAlinden TP, Prasad KM, Williams FE, Westerhof GR, Schornagel JH, Jansen G.
    Adv Enzyme Regul; 1992; 32():17-31. PubMed ID: 1323203
    [Abstract] [Full Text] [Related]

  • 2. Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.
    Jansen G, Westerhof GR, Jarmuszewski MJ, Kathmann I, Rijksen G, Schornagel JH.
    J Biol Chem; 1990 Oct 25; 265(30):18272-7. PubMed ID: 2211701
    [Abstract] [Full Text] [Related]

  • 3. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
    Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ.
    Adv Enzyme Regul; 1997 Oct 25; 37():59-76. PubMed ID: 9381986
    [Abstract] [Full Text] [Related]

  • 4. 5,10-Dideazatetrahydrofolic acid (DDATHF) transport in CCRF-CEM and MA104 cell lines.
    Pizzorno G, Cashmore AR, Moroson BA, Cross AD, Smith AK, Marling-Cason M, Kamen BA, Beardsley GP.
    J Biol Chem; 1993 Jan 15; 268(2):1017-23. PubMed ID: 8419310
    [Abstract] [Full Text] [Related]

  • 5. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.
    Dixon KH, Trepel JB, Eng SC, Cowan KH.
    Cancer Commun; 1991 Jan 15; 3(12):357-65. PubMed ID: 16296001
    [Abstract] [Full Text] [Related]

  • 6. Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization following affinity labeling.
    Yang CH, Sirotnak FM, Mines LS.
    J Biol Chem; 1988 Jul 15; 263(20):9703-9. PubMed ID: 2838477
    [Abstract] [Full Text] [Related]

  • 7. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G, Schornagel JH, Westerhof GR, Rijksen G, Newell DR, Jackman AL.
    Cancer Res; 1990 Dec 01; 50(23):7544-8. PubMed ID: 2253202
    [Abstract] [Full Text] [Related]

  • 8. Determinants of the disparate antitumor activities of (6R)-5,10-dideaza-5,6,7,8-tetrahydrofolate and methotrexate toward human lymphoblastic leukemia cells, characterized by severely impaired antifolate membrane transport.
    Matherly LH, Angeles SM, McGuire JJ.
    Biochem Pharmacol; 1993 Dec 14; 46(12):2185-95. PubMed ID: 7506026
    [Abstract] [Full Text] [Related]

  • 9. Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.
    Westerhof GR, Jansen G, van Emmerik N, Kathmann I, Rijksen G, Jackman AL, Schornagel JH.
    Cancer Res; 1991 Oct 15; 51(20):5507-13. PubMed ID: 1655252
    [Abstract] [Full Text] [Related]

  • 10. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G, Westerhof GR, Kathmann I, Rademaker BC, Rijksen G, Schornagel JH.
    Cancer Res; 1989 May 01; 49(9):2455-9. PubMed ID: 2706633
    [Abstract] [Full Text] [Related]

  • 11. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
    Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG.
    J Biol Chem; 1998 Nov 13; 273(46):30189-98. PubMed ID: 9804775
    [Abstract] [Full Text] [Related]

  • 12. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G.
    Biochem Pharmacol; 2002 Jan 15; 63(2):105-15. PubMed ID: 11841783
    [Abstract] [Full Text] [Related]

  • 13. Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line.
    Schuetz JD, Matherly LH, Westin EH, Goldman ID.
    J Biol Chem; 1988 Jul 15; 263(20):9840-7. PubMed ID: 2838483
    [Abstract] [Full Text] [Related]

  • 14. Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells.
    Drori S, Sprecher H, Shemer G, Jansen G, Goldman ID, Assaraf YG.
    Eur J Biochem; 2000 Feb 15; 267(3):690-702. PubMed ID: 10651805
    [Abstract] [Full Text] [Related]

  • 15. Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.
    Sierra EE, Brigle KE, Spinella MJ, Goldman ID.
    Biochem Pharmacol; 1995 Oct 12; 50(8):1287-94. PubMed ID: 7488246
    [Abstract] [Full Text] [Related]

  • 16. Cytotoxicity of methotrexate and trimetrexate and its reversal by folinic acid in human leukemic CCRF-CEM cells with carrier-mediated and receptor-mediated folate uptake.
    van der Veer LJ, Westerhof GR, Rijksen G, Schornagel JH, Jansen G.
    Leuk Res; 1989 Oct 12; 13(11):981-7. PubMed ID: 2532692
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H, Takemura Y, Kobayashi H, Ando Y.
    Jpn J Cancer Res; 1997 Sep 12; 88(9):900-6. PubMed ID: 9369939
    [Abstract] [Full Text] [Related]

  • 18. Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells.
    Spinella MJ, Brigle KE, Sierra EE, Goldman ID.
    J Biol Chem; 1995 Apr 07; 270(14):7842-9. PubMed ID: 7713875
    [Abstract] [Full Text] [Related]

  • 19. Role of N-glycosylation in the structure and function of the methotrexate membrane transporter from CCRF-CEM human lymphoblastic leukemia cells.
    Matherly LH, Angeles SM.
    Biochem Pharmacol; 1994 Mar 15; 47(6):1094-8. PubMed ID: 8147910
    [Abstract] [Full Text] [Related]

  • 20. Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.
    Assaraf YG, Rothem L, Hooijberg JH, Stark M, Ifergan I, Kathmann I, Dijkmans BA, Peters GJ, Jansen G.
    J Biol Chem; 2003 Feb 28; 278(9):6680-6. PubMed ID: 12486126
    [Abstract] [Full Text] [Related]

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