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129 related items for PubMed ID: 1323266

  • 1. Phosphodiesterase inhibition and positive inotropy in failing human myocardium.
    Schmitz W, Eschenhagen T, Mende U, Müller FU, Neumann J, Scholz H.
    Basic Res Cardiol; 1992; 87 Suppl 1():65-71. PubMed ID: 1323266
    [Abstract] [Full Text] [Related]

  • 2. Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations.
    von der Leyen H, Mende U, Meyer W, Neumann J, Nose M, Schmitz W, Scholz H, Starbatty J, Stein B, Wenzlaff H.
    Naunyn Schmiedebergs Arch Pharmacol; 1991 Jul; 344(1):90-100. PubMed ID: 1723153
    [Abstract] [Full Text] [Related]

  • 3. Effects of isomazole on force of contraction and phosphodiesterase isoenzymes I-IV in nonfailing and failing human hearts.
    Bethke T, Klimkiewicz A, Kohl C, von der Leyen H, Mehl H, Mende U, Meyer W, Neumann J, Schmitz W, Scholz H.
    J Cardiovasc Pharmacol; 1991 Sep; 18(3):386-97. PubMed ID: 1720839
    [Abstract] [Full Text] [Related]

  • 4. Characterization of the phosphodiesterase inhibition by 2-(3-methoxy-5-methylsulfinyl-2-thienyl)-1H-imidazo-(4,5-c)-pyridine HCl and its sulfide- and sulfone derivatives in myocardial preparations from failing human hearts.
    Bethke T, Klimkiewicz A, Meyer W, Schumacher C, Schmitz W, Scholz H, Starbatty J, Wenzlaff H, Zimmermann W.
    Arzneimittelforschung; 1995 Jul; 45(7):771-6. PubMed ID: 8573220
    [Abstract] [Full Text] [Related]

  • 5. Phosphodiesterase inhibition by enoximone in preparations from nonfailing and failing human hearts.
    Bethke T, Eschenhagen T, Klimkiewicz A, Kohl C, von der Leyen H, Mehl H, Mende U, Meyer W, Neumann J, Rosswag S.
    Arzneimittelforschung; 1992 Apr; 42(4):437-45. PubMed ID: 1386515
    [Abstract] [Full Text] [Related]

  • 6. Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart.
    Brunkhorst D, v der Leyen H, Meyer W, Nigbur R, Schmidt-Schumacher C, Scholz H.
    Naunyn Schmiedebergs Arch Pharmacol; 1989 May; 339(5):575-83. PubMed ID: 2549430
    [Abstract] [Full Text] [Related]

  • 7. Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium.
    Böhm M, Morano I, Pieske B, Rüegg JC, Wankerl M, Zimmermann R, Erdmann E.
    Circ Res; 1991 Mar; 68(3):689-701. PubMed ID: 1660359
    [Abstract] [Full Text] [Related]

  • 8. Effects of saterinone and its enantiomers R(+)-saterinone and S(-)-saterinone on the phosphodiesterase isoenzymes from ventricular tissue of failing human hearts and porcine hearts.
    Zimmermann W, Scholz H, Schumacher C, Wenzlaff H, Haverich A.
    Naunyn Schmiedebergs Arch Pharmacol; 1994 Jun; 349(6):611-8. PubMed ID: 7526225
    [Abstract] [Full Text] [Related]

  • 9. Selective inhibition of cAMP phosphodiesterase III activity by the cardiotonic agent saterinone in guinea pig myocardium.
    Brunkhorst D, von der Leyen H, Meyer W, Schmidt-Schumacher C, Scholz H.
    Arzneimittelforschung; 1988 Sep; 38(9):1293-8. PubMed ID: 2852013
    [Abstract] [Full Text] [Related]

  • 10. Effects of a cardiotonic quinolinone derivative Y-20487 on the isoproterenol-induced positive inotropic action and cyclic AMP accumulation in rat ventricular myocardium: comparison with rolipram, Ro 20-1724, milrinone, and isobutylmethylxanthine.
    Katano Y, Endoh M.
    J Cardiovasc Pharmacol; 1992 Sep; 20(5):715-22. PubMed ID: 1280732
    [Abstract] [Full Text] [Related]

  • 11. Comparison of cyclic nucleotide phosphodiesterase isoenzymes in rat and rabbit ventricular myocardium: positive inotropic and phosphodiesterase inhibitory effects of Org 30029, milrinone and rolipram.
    Shahid M, Nicholson CD.
    Naunyn Schmiedebergs Arch Pharmacol; 1990 Dec; 342(6):698-705. PubMed ID: 1710786
    [Abstract] [Full Text] [Related]

  • 12. Phosphodiesterase isozyme inhibition, activation of the cAMP system, and positive inotropy mediated by milrinone in isolated guinea pig cardiac muscle.
    Silver PJ, Harris AL, Canniff PC, Lepore RE, Bentley RG, Hamel LT, Evans DB.
    J Cardiovasc Pharmacol; 1989 Apr; 13(4):530-40. PubMed ID: 2470989
    [Abstract] [Full Text] [Related]

  • 13. Protein phosphorylation in isolated trabeculae from nonfailing and failing human hearts.
    Bartel S, Stein B, Eschenhagen T, Mende U, Neumann J, Schmitz W, Krause EG, Karczewski P, Scholz H.
    Mol Cell Biochem; 1989 Apr; 157(1-2):171-9. PubMed ID: 8739244
    [Abstract] [Full Text] [Related]

  • 14. High selectivity for inhibition of phosphodiesterase III and positive inotropic effects of MCI-154 in guinea pig myocardium.
    Bethke T, Meyer W, Schmitz W, Scholz H, Wenzlaff H, Armah BI, Brückner R, Raap A.
    J Cardiovasc Pharmacol; 1993 Jun; 21(6):847-55. PubMed ID: 7687707
    [Abstract] [Full Text] [Related]

  • 15. Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts.
    Bethke T, Brunkhorst D, von der Leyen H, Meyer W, Nigbur R, Scholz H.
    Naunyn Schmiedebergs Arch Pharmacol; 1988 May; 337(5):576-82. PubMed ID: 2457816
    [Abstract] [Full Text] [Related]

  • 16. Reduced alpha 1- and beta 2-adrenoceptor-mediated positive inotropic effects in human end-stage heart failure.
    Steinfath M, Danielsen W, von der Leyen H, Mende U, Meyer W, Neumann J, Nose M, Reich T, Schmitz W, Scholz H.
    Br J Pharmacol; 1992 Feb; 105(2):463-9. PubMed ID: 1348446
    [Abstract] [Full Text] [Related]

  • 17. EMD 53998 acts as Ca(2+)-sensitizer and phosphodiesterase III-inhibitor in human myocardium.
    Uhlmann R, Schwinger RH, Lues I, Erdmann E.
    Basic Res Cardiol; 1995 Feb; 90(5):365-71. PubMed ID: 8585857
    [Abstract] [Full Text] [Related]

  • 18. Positive inotropic activity of 5-amino-6-cyano-1,3-dimethyl-1,2,3,4-tetrahydropyrido[2,3-d]pyrim idine-2,4-dione in cardiac muscle from guinea-pig and man. Part 6: Compounds with positive inotropic activity.
    Heber D, Heers C, Ravens U.
    Pharmazie; 1993 Jul; 48(7):537-41. PubMed ID: 7692456
    [Abstract] [Full Text] [Related]

  • 19. Effects of the triazolopyrimidine trapidil on force of contraction, beating frequency and phosphodiesterase I--IV activity in guinea-pig hearts.
    Bethke T, Mehl H, Meyer W, Schmitz W, Scholz H, Thomas K, Wenzlaff H.
    Arzneimittelforschung; 1991 May; 41(5):461-8. PubMed ID: 1716891
    [Abstract] [Full Text] [Related]

  • 20. Differential effects of phosphodiesterase inhibitors on accumulation of cyclic AMP in isolated ventricular cardiomyocytes.
    Kelso EJ, McDermott BJ, Silke B.
    Biochem Pharmacol; 1995 Feb 14; 49(4):441-52. PubMed ID: 7872950
    [Abstract] [Full Text] [Related]

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