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Journal Abstract Search

120 related items for PubMed ID: 1324317

  • 1. Benzothiazole hydroxy ureas as inhibitors of 5-lipoxygenase: use of the hydroxyurea moiety as a replacement for hydroxamic acid.
    Greco MN, Hageman WE, Powell ET, Tighe JJ, Persico FJ.
    J Med Chem; 1992 Aug 21; 35(17):3180-3. PubMed ID: 1324317
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors.
    Phillips OA, Bosso MA, Ezeamuzie CI.
    J Enzyme Inhib Med Chem; 2020 Dec 21; 35(1):1471-1482. PubMed ID: 32635785
    [Abstract] [Full Text] [Related]

  • 3. N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase.
    Connolly PJ, Wetter SK, Beers KN, Hamel SC, Chen RH, Wachter MP, Ansell J, Singer MM, Steber M, Ritchie DM, Argentieri DC.
    Bioorg Med Chem Lett; 1999 Apr 05; 9(7):979-84. PubMed ID: 10230624
    [Abstract] [Full Text] [Related]

  • 4. Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors.
    Satoh Y, Stanton JL, Hutchison AJ, Libby AH, Kowalski TJ, Lee WH, White DH, Kimble EF.
    J Med Chem; 1993 Nov 12; 36(23):3580-94. PubMed ID: 8246226
    [Abstract] [Full Text] [Related]

  • 5. Azole phenoxy hydroxyureas as selective and orally active inhibitors of 5-lipoxygenase.
    Malamas MS, Carlson RP, Grimes D, Howell R, Glaser K, Gunawan I, Nelson JA, Kanzelberger M, Shah U, Hartman DA.
    J Med Chem; 1996 Jan 05; 39(1):237-45. PubMed ID: 8568813
    [Abstract] [Full Text] [Related]

  • 6. New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition.
    Chiasson AI, Robichaud S, Ndongou Moutombi FJ, Hébert MPA, Mbarik M, Surette ME, Touaibia M.
    Molecules; 2020 Oct 14; 25(20):. PubMed ID: 33066378
    [Abstract] [Full Text] [Related]

  • 7. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
    Oketani K, Nagakura N, Harada K, Inoue T.
    Eur J Pharmacol; 2001 Jun 22; 422(1-3):209-16. PubMed ID: 11430933
    [Abstract] [Full Text] [Related]

  • 8. Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase.
    Lau CK, Bélanger PC, Dufresne C, Scheigetz J, Therien M, Fitzsimmons B, Young RN, Ford-Hutchinson AW, Riendeau D, Denis D.
    J Med Chem; 1992 Apr 03; 35(7):1299-318. PubMed ID: 1313879
    [Abstract] [Full Text] [Related]

  • 9. Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma.
    Payne AN, Jackson WP, Salmon JA, Nicholls A, Yeadon M, Garland LG.
    Agents Actions Suppl; 1991 Apr 03; 34():189-99. PubMed ID: 1793063
    [Abstract] [Full Text] [Related]

  • 10. Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
    Jiang B, Huang X, Yao H, Jiang J, Wu X, Jiang S, Wang Q, Lu T, Xu J.
    Org Biomol Chem; 2014 Apr 07; 12(13):2114-27. PubMed ID: 24562695
    [Abstract] [Full Text] [Related]

  • 11. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR, Tegeler JJ, Kurtz ES, Allen RC, Bailey SC, Elliott ME, Hellyer L, Helsley GC, Przekop P, Freed BS, White J, Martin LL.
    J Med Chem; 1996 Jan 05; 39(1):246-52. PubMed ID: 8568814
    [Abstract] [Full Text] [Related]

  • 12. Methoxytetrahydropyrans. A new series of selective and orally potent 5-lipoxygenase inhibitors.
    Crawley GC, Dowell RI, Edwards PN, Foster SJ, McMillan RM, Walker ER, Waterson D, Bird TG, Bruneau P, Giroaeau JM.
    J Med Chem; 1992 Jul 10; 35(14):2600-9. PubMed ID: 1321908
    [Abstract] [Full Text] [Related]

  • 13. Novel bishydroxamic acids as 5-lipoxygenase inhibitors.
    Ohemeng KA, Nguyen VN, Schwender CF, Singer M, Steber M, Ansell J, Hageman W.
    Bioorg Med Chem; 1994 Mar 10; 2(3):187-93. PubMed ID: 7922131
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.
    Salmon JA, Jackson WP, Garland LG.
    Adv Prostaglandin Thromboxane Leukot Res; 1991 Mar 10; 21A():109-12. PubMed ID: 1847758
    [No Abstract] [Full Text] [Related]

  • 15. Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3-pyridyl)-alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase.
    Hibi S, Okamoto Y, Tagami K, Numata H, Kobayashi N, Shinoda M, Kawahara T, Harada K, Miyamoto K, Yamatsu I.
    J Med Chem; 1996 Aug 02; 39(16):3148-57. PubMed ID: 8759636
    [Abstract] [Full Text] [Related]

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  • 17. Nitroxide metabolites from alkylhydroxylamines and N-hydroxyurea derivatives resulting from reductive inhibition of soybean lipoxygenase.
    Chamulitrat W, Mason RP, Riendeau D.
    J Biol Chem; 1992 May 15; 267(14):9574-9. PubMed ID: 1315759
    [Abstract] [Full Text] [Related]

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  • 19. Criteria for the identification of non-redox inhibitors of 5-lipoxygenase.
    Falgueyret JP, Hutchinson JH, Riendeau D.
    Biochem Pharmacol; 1993 Feb 24; 45(4):978-81. PubMed ID: 8452572
    [Abstract] [Full Text] [Related]

  • 20. N-Aminoindoline derivatives as inhibitors of 5-lipoxygenase.
    Audouin C, Mestdagh N, Lassoie MA, Houssin R, Hénichart JP.
    Bioorg Med Chem Lett; 2001 Mar 26; 11(6):845-8. PubMed ID: 11277534
    [Abstract] [Full Text] [Related]

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