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Journal Abstract Search

167 related items for PubMed ID: 1329989

  • 1. Structural features of the antibody-A chain linkage that influence the activity and stability of ricin A chain immunotoxins.
    Cumber AJ, Westwood JH, Henry RV, Parnell GD, Coles BF, Wawrzynczak EJ.
    Bioconjug Chem; 1992; 3(5):397-401. PubMed ID: 1329989
    [Abstract] [Full Text] [Related]

  • 2. Stability and cytotoxicity of Fab-ricin A immunotoxins prepared with water soluble long chain heterobifunctional crosslinking agents.
    Woo BH, Lee JT, Park MO, Lee KR, Han JW, Park ES, Yoo SD, Lee KC.
    Arch Pharm Res; 1999 Oct; 22(5):459-63. PubMed ID: 10549572
    [Abstract] [Full Text] [Related]

  • 3. New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.
    Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, Knyba RE, Wawrzynczak EJ, Blakey DC.
    Cancer Res; 1987 Nov 15; 47(22):5924-31. PubMed ID: 3499221
    [Abstract] [Full Text] [Related]

  • 4. Enhanced stability in vitro and in vivo of immunoconjugates prepared with 5-methyl-2-iminothiolane.
    Carroll SF, Bernhard SL, Goff DA, Bauer RJ, Leach W, Kung AH.
    Bioconjug Chem; 1994 Nov 15; 5(3):248-56. PubMed ID: 7918744
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics in the rat of a panel of immunotoxins made with abrin A chain, ricin A chain, gelonin, and momordin.
    Wawrzynczak EJ, Cumber AJ, Henry RV, May J, Newell DR, Parnell GD, Worrell NR, Forrester JA.
    Cancer Res; 1990 Dec 01; 50(23):7519-26. PubMed ID: 2253201
    [Abstract] [Full Text] [Related]

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  • 7. Role of cross-linking agents in determining the biochemical and pharmacokinetic properties of Mgr6-clavin immunotoxins.
    Dosio F, Arpicco S, Adobati E, Canevari S, Brusa P, De Santis R, Parente D, Pignanelli P, Negri DR, Colnaghi MI, Cattel L.
    Bioconjug Chem; 1998 Dec 01; 9(3):372-81. PubMed ID: 9576812
    [Abstract] [Full Text] [Related]

  • 8. Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages.
    Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, Blakey DC, Newell DR.
    Cancer Res; 1988 Nov 15; 48(22):6396-403. PubMed ID: 3263186
    [Abstract] [Full Text] [Related]

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  • 10. Thiol-containing cross-linking agent with enhanced steric hindrance.
    Greenfield L, Bloch W, Moreland M.
    Bioconjug Chem; 1990 Nov 15; 1(6):400-10. PubMed ID: 2129154
    [Abstract] [Full Text] [Related]

  • 11. The effect of ricin B chain on the intracellular trafficking of an A chain immunotoxin.
    Timar J, McIntosh DP, Henry R, Cumber AJ, Parnell GD, Davies AJ.
    Br J Cancer; 1991 Oct 15; 64(4):655-62. PubMed ID: 1911213
    [Abstract] [Full Text] [Related]

  • 12. Comparison of the selective cytotoxic effects of immunotoxins containing ricin A chain or pokeweed antiviral protein and anti-Thy 1.1 monoclonal antibodies.
    Ramakrishnan S, Houston LL.
    Cancer Res; 1984 Jan 15; 44(1):201-8. PubMed ID: 6140077
    [Abstract] [Full Text] [Related]

  • 13. Laboratory preparation of a deglycosylated ricin toxin A chain containing immunotoxin directed against a CD7 T lineage differentiation antigen for phase I human clinical studies involving T cell malignancies.
    Vallera DA, Burns LJ, Frankel AE, Sicheneder AR, Gunther R, Gajl-Peczalska K, Pennell CA, Kersey JH.
    J Immunol Methods; 1996 Oct 16; 197(1-2):69-83. PubMed ID: 8890895
    [Abstract] [Full Text] [Related]

  • 14. Cytotoxic effects of ricin without an interchain disulfide bond: genetic modification and chemical crosslinking studies.
    Mohanraj D, Ramakrishnan S.
    Biochim Biophys Acta; 1995 Apr 13; 1243(3):399-406. PubMed ID: 7727515
    [Abstract] [Full Text] [Related]

  • 15. Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: antitumor effects, in vivo fate, and tumor cell mutants.
    Thorpe PE, Blakey DC, Brown AN, Knowles PP, Knyba RE, Wallace PM, Watson GJ, Wawrzynczak EJ.
    J Natl Cancer Inst; 1987 Nov 13; 79(5):1101-12. PubMed ID: 2890786
    [Abstract] [Full Text] [Related]

  • 16. Blocked and non-blocked ricin immunotoxins against the CD4 antigen exhibit higher cytotoxic potency than a ricin A chain immunotoxin potentiated with ricin B chain or with a ricin B chain immunotoxin.
    Wawrzynczak EJ, Watson GJ, Cumber AJ, Henry RV, Parnell GD, Rieber EP, Thorpe PE.
    Cancer Immunol Immunother; 1991 Nov 13; 32(5):289-95. PubMed ID: 1998970
    [Abstract] [Full Text] [Related]

  • 17. Enhanced stability of an immunotoxin made with abrin A chain and a hindered disulphide cross-linker.
    Cumber A, Wawrzynczak E.
    Biochem Soc Trans; 1992 Nov 13; 20(4):312S. PubMed ID: 1486982
    [No Abstract] [Full Text] [Related]

  • 18. Generation and characterization of an anti-CD19 single-chain Fv immunotoxin composed of C-terminal disulfide-linked dgRTA.
    Wang D, Li Q, Hudson W, Berven E, Uckun F, Kersey JH.
    Bioconjug Chem; 1997 Nov 13; 8(6):878-84. PubMed ID: 9404661
    [Abstract] [Full Text] [Related]

  • 19. Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein alpha-sarcin from Aspergillus giganteus.
    Wawrzynczak EJ, Henry RV, Cumber AJ, Parnell GD, Derbyshire EJ, Ulbrich N.
    Eur J Biochem; 1991 Feb 26; 196(1):203-9. PubMed ID: 2001699
    [Abstract] [Full Text] [Related]

  • 20. Novel synthesis and in vitro characterization of disulfide-linked ricin-monoclonal antibody conjugates devoid of galactose binding activity.
    Pietersz GA, Kanellos J, McKenzie IF.
    Cancer Res; 1988 Aug 15; 48(16):4469-76. PubMed ID: 3260814
    [Abstract] [Full Text] [Related]

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