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727 related items for PubMed ID: 1335058

  • 1. Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity.
    Torphy TJ, Zhou HL, Cieslinski LB.
    J Pharmacol Exp Ther; 1992 Dec; 263(3):1195-205. PubMed ID: 1335058
    [Abstract] [Full Text] [Related]

  • 2. Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes.
    Seldon PM, Barnes PJ, Giembycz MA.
    Cell Biochem Biophys; 1998 Dec; 29(1-2):179-201. PubMed ID: 9631245
    [Abstract] [Full Text] [Related]

  • 3. Characterization and selective inhibition of cyclic nucleotide phosphodiesterase isozymes in canine tracheal smooth muscle.
    Torphy TJ, Cieslinski LB.
    Mol Pharmacol; 1990 Feb; 37(2):206-14. PubMed ID: 2154670
    [Abstract] [Full Text] [Related]

  • 4. Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase.
    Seldon PM, Barnes PJ, Meja K, Giembycz MA.
    Mol Pharmacol; 1995 Oct; 48(4):747-57. PubMed ID: 7476903
    [Abstract] [Full Text] [Related]

  • 5. Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
    Manning CD, McLaughlin MM, Livi GP, Cieslinski LB, Torphy TJ, Barnette MS.
    J Pharmacol Exp Ther; 1996 Feb; 276(2):810-8. PubMed ID: 8632354
    [Abstract] [Full Text] [Related]

  • 6. Identification, characterization, and functional role of phosphodiesterase type IV in cerebral vessels: effects of selective phosphodiesterase inhibitors.
    Willette RN, Shiloh AO, Sauermelch CF, Sulpizio A, Michell MP, Cieslinski LB, Torphy TJ, Ohlstein EH.
    J Cereb Blood Flow Metab; 1997 Feb; 17(2):210-9. PubMed ID: 9040501
    [Abstract] [Full Text] [Related]

  • 7. Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle.
    Torphy TJ, Undem BJ, Cieslinski LB, Luttmann MA, Reeves ML, Hay DW.
    J Pharmacol Exp Ther; 1993 Jun; 265(3):1213-23. PubMed ID: 8389856
    [Abstract] [Full Text] [Related]

  • 8. Modulation of rat thymocyte proliferative response through the inhibition of different cyclic nucleotide phosphodiesterase isoforms by means of selective inhibitors and cGMP-elevating agents.
    Marcoz P, Prigent AF, Lagarde M, Nemoz G.
    Mol Pharmacol; 1993 Nov; 44(5):1027-35. PubMed ID: 8246905
    [Abstract] [Full Text] [Related]

  • 9. Regulation of distinct cyclic AMP-specific phosphodiesterase (phosphodiesterase type 4) isozymes in human monocytic cells.
    Verghese MW, McConnell RT, Lenhard JM, Hamacher L, Jin SL.
    Mol Pharmacol; 1995 Jun; 47(6):1164-71. PubMed ID: 7603456
    [Abstract] [Full Text] [Related]

  • 10. Potentiation of erectile response and cAMP accumulation by combination of prostaglandin E1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE 4).
    Bivalacqua TJ, Champion HC, Rajasekaran M, Sikka SC, Kadowitz PJ, Doherty PC, Hellstrom WJ.
    J Urol; 1999 Nov; 162(5):1848-55. PubMed ID: 10524946
    [Abstract] [Full Text] [Related]

  • 11. Distinct profiles of phosphodiesterase isozymes in cultured cells derived from nonpigmented and pigmented ocular ciliary epithelium.
    Bode DC, Hamel LT, Wax MB.
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1286-91. PubMed ID: 8263791
    [Abstract] [Full Text] [Related]

  • 12. Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro.
    Truss MC, Uckert S, Stief CG, Schulz-Knappe P, Hess R, Forssmann WG, Jonas U.
    Urology; 1995 May; 45(5):893-901. PubMed ID: 7747383
    [Abstract] [Full Text] [Related]

  • 13. Effect of adrenaline and glucocorticoids on monocyte cAMP-specific phosphodiesterase (PDE4) in a monocytic cell line.
    Delgado M, Fernández-Alfonso MS, Fuentes A.
    Arch Dermatol Res; 2002 Jul; 294(4):190-7. PubMed ID: 12111350
    [Abstract] [Full Text] [Related]

  • 14. Correlation of cell-free brain cyclic nucleotide phosphodiesterase activities to cyclic AMP decay in intact brain slices.
    Whalin ME, Garrett RL, Thompson WJ, Strada SJ.
    Second Messengers Phosphoproteins; 2002 Jul; 12(5-6):311-25. PubMed ID: 2856115
    [Abstract] [Full Text] [Related]

  • 15. Role of cyclic nucleotide phosphodiesterase isozymes in intact canine trachealis.
    Torphy TJ, Zhou HL, Burman M, Huang LB.
    Mol Pharmacol; 1991 Mar; 39(3):376-84. PubMed ID: 1848659
    [Abstract] [Full Text] [Related]

  • 16. Characterization of phosphodiesterase 4 in guinea-pig macrophages: multiple activities, association states and sensitivity to selective inhibitors.
    Kelly JJ, Barnes PJ, Giembycz MA.
    Br J Pharmacol; 1998 May; 124(1):129-40. PubMed ID: 9630352
    [Abstract] [Full Text] [Related]

  • 17. Initial biochemical and functional characterization of cyclic nucleotide phosphodiesterase isozymes in canine colonic smooth muscle.
    Barnette MS, Manning CD, Price WJ, Barone FC.
    J Pharmacol Exp Ther; 1993 Feb; 264(2):801-12. PubMed ID: 7679736
    [Abstract] [Full Text] [Related]

  • 18. Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases.
    Michie AM, Rena G, Harnett MM, Houslay MD.
    Cell Biochem Biophys; 1998 Feb; 28(2-3):161-85. PubMed ID: 9515165
    [Abstract] [Full Text] [Related]

  • 19. Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol.
    Dent G, Giembycz MA, Evans PM, Rabe KF, Barnes PJ.
    J Pharmacol Exp Ther; 1994 Dec; 271(3):1167-74. PubMed ID: 7996422
    [Abstract] [Full Text] [Related]

  • 20. delta-Opioid receptor activates cAMP phosphodiesterase activities in neuroblastoma x glioma NG108-15 hybrid cells.
    Law PY, Loh HH.
    Mol Pharmacol; 1993 May; 43(5):684-93. PubMed ID: 8388986
    [Abstract] [Full Text] [Related]


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