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Journal Abstract Search

189 related items for PubMed ID: 1348448

  • 1. Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue.
    Hendricks CB, Rowinsky EK, Grochow LB, Donehower RC, Kaufmann SH.
    Cancer Res; 1992 Apr 15; 52(8):2268-78. PubMed ID: 1348448
    [Abstract] [Full Text] [Related]

  • 2. Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations.
    Yang CJ, Horton JK, Cowan KH, Schneider E.
    Cancer Res; 1995 Sep 15; 55(18):4004-9. PubMed ID: 7664272
    [Abstract] [Full Text] [Related]

  • 3. Synergistic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864).
    Mattern MR, Hofmann GA, McCabe FL, Johnson RK.
    Cancer Res; 1991 Nov 01; 51(21):5813-6. PubMed ID: 1657371
    [Abstract] [Full Text] [Related]

  • 4. Phase I and pharmacodynamic study of the topoisomerase I-inhibitor topotecan in patients with refractory acute leukemia.
    Rowinsky EK, Adjei A, Donehower RC, Gore SD, Jones RJ, Burke PJ, Cheng YC, Grochow LB, Kaufmann SH.
    J Clin Oncol; 1994 Oct 01; 12(10):2193-203. PubMed ID: 7931489
    [Abstract] [Full Text] [Related]

  • 5. Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines.
    Vanhoefer U, Müller MR, Hilger RA, Lindtner B, Klaassen U, Schleucher N, Rustum YM, Seeber S, Harstrick A.
    Br J Cancer; 1999 Dec 01; 81(8):1304-10. PubMed ID: 10604726
    [Abstract] [Full Text] [Related]

  • 6. Caffeine prevents apoptosis and cell cycle effects induced by camptothecin or topotecan in HL-60 cells.
    Traganos F, Kapuscinski J, Gong J, Ardelt B, Darzynkiewicz RJ, Darzynkiewicz Z.
    Cancer Res; 1993 Oct 01; 53(19):4613-8. PubMed ID: 8402636
    [Abstract] [Full Text] [Related]

  • 7. Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
    Rappa G, Lorico A, Sartorelli AC.
    Cancer Res; 1993 Nov 15; 53(22):5487-93. PubMed ID: 8106148
    [Abstract] [Full Text] [Related]

  • 8. Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells.
    Nakagawa M, Schneider E, Dixon KH, Horton J, Kelley K, Morrow C, Cowan KH.
    Cancer Res; 1992 Nov 15; 52(22):6175-81. PubMed ID: 1358431
    [Abstract] [Full Text] [Related]

  • 9. Role of differential drug uptake, efflux, and binding of etoposide in sensitive and resistant human tumor cell lines: implications for the mechanisms of drug resistance.
    Politi PM, Sinha BK.
    Mol Pharmacol; 1989 Mar 15; 35(3):271-8. PubMed ID: 2564628
    [Abstract] [Full Text] [Related]

  • 10. Binding of an optically pure photoaffinity analogue of verapamil, LU-49888, to P-glycoprotein from multidrug-resistant human leukemic cell lines.
    Qian XD, Beck WT.
    Cancer Res; 1990 Feb 15; 50(4):1132-7. PubMed ID: 1967551
    [Abstract] [Full Text] [Related]

  • 11. RNA synthesis inhibitors alter the subnuclear distribution of DNA topoisomerase I.
    Buckwalter CA, Lin AH, Tanizawa A, Pommier YG, Cheng YC, Kaufmann SH.
    Cancer Res; 1996 Apr 01; 56(7):1674-81. PubMed ID: 8603419
    [Abstract] [Full Text] [Related]

  • 12. P-glycoprotein-independent mechanism of resistance to VP-16 in multidrug-resistant tumor cell lines: pharmacokinetic and photoaffinity labeling studies.
    Politi PM, Arnold ST, Felsted RL, Sinha BK.
    Mol Pharmacol; 1990 Jun 01; 37(6):790-6. PubMed ID: 1972771
    [Abstract] [Full Text] [Related]

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  • 14. Differential interactions of Pgp inhibitor thaliblastine with adriamycin, etoposide, taxol and anthrapyrazole CI941 in sensitive and multidrug-resistant human MCF-7 breast cancer cells.
    Chen G, Teicher BA, Frei E.
    Anticancer Res; 1996 Jun 01; 16(6B):3499-505. PubMed ID: 9042212
    [Abstract] [Full Text] [Related]

  • 15. Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines.
    Slovak ML, Hoeltge GA, Dalton WS, Trent JM.
    Cancer Res; 1988 May 15; 48(10):2793-7. PubMed ID: 2896069
    [Abstract] [Full Text] [Related]

  • 16. Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH.
    Gabr A, Kuin A, Aalders M, El-Gawly H, Smets LA.
    Cancer Res; 1997 Nov 01; 57(21):4811-6. PubMed ID: 9354443
    [Abstract] [Full Text] [Related]

  • 17. Subcellular redistribution of DNA topoisomerase I in anaplastic astrocytoma cells treated with topotecan.
    Danks MK, Garrett KE, Marion RC, Whipple DO.
    Cancer Res; 1996 Apr 01; 56(7):1664-73. PubMed ID: 8603418
    [Abstract] [Full Text] [Related]

  • 18. DNA repair enzyme, O6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors.
    Kuo CC, Liu JF, Chang JY.
    J Pharmacol Exp Ther; 2006 Feb 01; 316(2):946-54. PubMed ID: 16258022
    [Abstract] [Full Text] [Related]

  • 19. Increased expression of DNA topoisomerase I gene and collateral sensitivity to camptothecin in human cisplatin-resistant bladder cancer cells.
    Kotoh S, Naito S, Yokomizo A, Kumazawa J, Asakuno K, Kohno K, Kuwano M.
    Cancer Res; 1994 Jun 15; 54(12):3248-52. PubMed ID: 8205547
    [Abstract] [Full Text] [Related]

  • 20. A phase I and translational study of sequential administration of the topoisomerase I and II inhibitors topotecan and etoposide.
    Hammond LA, Eckardt JR, Ganapathi R, Burris HA, Rodriguez GA, Eckhardt SG, Rothenberg ML, Weiss GR, Kuhn JG, Hodges S, Von Hoff DD, Rowinsky EK.
    Clin Cancer Res; 1998 Jun 15; 4(6):1459-67. PubMed ID: 9626463
    [Abstract] [Full Text] [Related]

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