These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Inhibition of cystine uptake disrupts the growth of primary brain tumors. Chung WJ, Lyons SA, Nelson GM, Hamza H, Gladson CL, Gillespie GY, Sontheimer H. J Neurosci; 2005 Aug 03; 25(31):7101-10. PubMed ID: 16079392 [Abstract] [Full Text] [Related]
23. Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc- protects from oxidative glutamate toxicity. Lewerenz J, Klein M, Methner A. J Neurochem; 2006 Aug 03; 98(3):916-25. PubMed ID: 16771835 [Abstract] [Full Text] [Related]
24. Induction of cystine transport activity in mouse peritoneal macrophages. Watanabe H, Bannai S. J Exp Med; 1987 Mar 01; 165(3):628-40. PubMed ID: 2880923 [Abstract] [Full Text] [Related]
25. Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake. Wegrzynowicz M, Hilgier W, Dybel A, Oja SS, Saransaari P, Albrecht J. Neurochem Int; 2007 Jun 01; 50(7-8):883-9. PubMed ID: 17239489 [Abstract] [Full Text] [Related]
26. Transport of cystine and cysteine and cell growth in cultured human diploid fibroblasts: effect of glutamate and homocysteate. Bannai S, Ishii T. J Cell Physiol; 1982 Aug 01; 112(2):265-72. PubMed ID: 6126484 [Abstract] [Full Text] [Related]
27. Hydrogen peroxide triggers an increase in cell surface expression of system xc- in cultured human glioma cells. Chase LA, VerHeulen Kleyn M, Schiller N, King AG, Flores G, Engelsman SB, Bowles C, Smith SL, Robinson AE, Rothstein J. Neurochem Int; 2020 Mar 01; 134():104648. PubMed ID: 31874187 [Abstract] [Full Text] [Related]
28. FGF-2 induces neuronal death through upregulation of system xc-. Liu X, Albano R, Lobner D. Brain Res; 2014 Feb 14; 1547():25-33. PubMed ID: 24374066 [Abstract] [Full Text] [Related]
29. Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca2+ permeable AMPA receptor-system xc- pathway. Wang XY, Li YL, Wang HY, Zhu M, Guo D, Wang GL, Gao YT, Yang Z, Li T, Yang CY, Chen YM. Toxicol In Vitro; 2017 Oct 14; 44():57-65. PubMed ID: 28663055 [Abstract] [Full Text] [Related]
30. Substance P regulation of glutamate and cystine transport in human astrocytoma cells. Johnson CL, Johnson CG. Recept Channels; 1993 Oct 14; 1(1):53-9. PubMed ID: 7521733 [Abstract] [Full Text] [Related]
31. The glutathione level of retinal Müller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate. Reichelt W, Stabel-Burow J, Pannicke T, Weichert H, Heinemann U. Neuroscience; 1997 Apr 14; 77(4):1213-24. PubMed ID: 9130799 [Abstract] [Full Text] [Related]
32. Role of glutamate transporters in the regulation of glutathione levels in human macrophages. Rimaniol AC, Mialocq P, Clayette P, Dormont D, Gras G. Am J Physiol Cell Physiol; 2001 Dec 14; 281(6):C1964-70. PubMed ID: 11698255 [Abstract] [Full Text] [Related]
33. The cystine/glutamate antiporter regulates dendritic cell differentiation and antigen presentation. D'Angelo JA, Dehlink E, Platzer B, Dwyer P, Circu ML, Garay J, Aw TY, Fiebiger E, Dickinson BL. J Immunol; 2010 Sep 15; 185(6):3217-26. PubMed ID: 20733204 [Abstract] [Full Text] [Related]
35. Role of proton dissociation in the transport of cystine and glutamate in human diploid fibroblasts in culture. Bannai S, Kitamura E. J Biol Chem; 1981 Jun 10; 256(11):5770-2. PubMed ID: 6113240 [Abstract] [Full Text] [Related]
36. Endothelial cell cystine uptake and glutathione increase with N,N-bis(2-chloroethyl)-N-nitrosourea exposure. Deneke SM, Lawrence RA, Jenkinson SG. Am J Physiol; 1992 Mar 10; 262(3 Pt 1):L301-4. PubMed ID: 1550253 [Abstract] [Full Text] [Related]
37. Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion. Sleire L, Skeie BS, Netland IA, Førde HE, Dodoo E, Selheim F, Leiss L, Heggdal JI, Pedersen PH, Wang J, Enger PØ. Oncogene; 2015 Dec 03; 34(49):5951-9. PubMed ID: 25798841 [Abstract] [Full Text] [Related]
38. beta-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc(-). Liu X, Rush T, Zapata J, Lobner D. Exp Neurol; 2009 Jun 03; 217(2):429-33. PubMed ID: 19374900 [Abstract] [Full Text] [Related]
39. The xc- cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine. Guan J, Lo M, Dockery P, Mahon S, Karp CM, Buckley AR, Lam S, Gout PW, Wang YZ. Cancer Chemother Pharmacol; 2009 Aug 03; 64(3):463-72. PubMed ID: 19104813 [Abstract] [Full Text] [Related]