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Journal Abstract Search

164 related items for PubMed ID: 1361572

  • 1. DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles.
    Tam SW, Steinfels GF, Gilligan PJ, Schmidt WK, Cook L.
    J Pharmacol Exp Ther; 1992 Dec; 263(3):1167-74. PubMed ID: 1361572
    [Abstract] [Full Text] [Related]

  • 2. DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects.
    Cook L, Tam SW, Rohrbach KW.
    J Pharmacol Exp Ther; 1992 Dec; 263(3):1159-66. PubMed ID: 1361571
    [Abstract] [Full Text] [Related]

  • 3. [3H]1-(cyclopropylmethyl)-4-(2-(4-fluorophenyl)-2-oxoethyl) piperidine HBr (DuP 734). A selective ligand for sigma receptors in mouse brain in vivo.
    Watanabe M, Rominger D, Hurt SD, De Souza EB, Tam SW.
    J Pharmacol Exp Ther; 1993 Sep; 266(3):1541-8. PubMed ID: 8371156
    [Abstract] [Full Text] [Related]

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  • 5. The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5-hydroxytryptamine2A receptor antagonist, in rats.
    Okuyama S, Chaki S, Kawashima N, Suzuki Y, Ogawa S, Kumagai T, Nakazato A, Nagamine M, Yamaguchi K, Tomisawa K.
    Br J Pharmacol; 1997 Jun; 121(3):515-25. PubMed ID: 9179395
    [Abstract] [Full Text] [Related]

  • 6. In vitro and in vivo characterization of the dopamine D4 receptor, serotonin 5-HT2A receptor and alpha-1 adrenoceptor antagonist (R)-(+)-2-amino-4-(4-fluorophenyl)-5-[1-[4-(4-fluorophenyl)-4-oxobutyl] pyrrolidin-3-yl]thiazole (NRA0045).
    Okuyama S, Chaki S, Yoshikawa R, Suzuki Y, Ogawa S, Imagawa Y, Kawashima N, Ikeda Y, Kumagai T, Nakazato A, Nagamine M, Tomisawa K.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):56-63. PubMed ID: 9223539
    [Abstract] [Full Text] [Related]

  • 7. Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
    Oka M, Noda Y, Ochi Y, Furukawa K, Une T, Kurumiya S, Hino K, Karasawa T.
    J Pharmacol Exp Ther; 1993 Jan; 264(1):158-65. PubMed ID: 8093723
    [Abstract] [Full Text] [Related]

  • 8. Pharmacological profile of MS-377, a novel antipsychotic agent with selective affinity for sigma receptors.
    Takahashi S, Sonehara K, Takagi K, Miwa T, Horikomi K, Mita N, Nagase H, Iizuka K, Sakai K.
    Psychopharmacology (Berl); 1999 Aug; 145(3):295-302. PubMed ID: 10494578
    [Abstract] [Full Text] [Related]

  • 9. Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.
    Largent BL, Gundlach AL, Snyder SH.
    J Pharmacol Exp Ther; 1986 Aug; 238(2):739-48. PubMed ID: 3016248
    [Abstract] [Full Text] [Related]

  • 10. 5-hydroxytryptamine (5-HT)1A receptors and the tail-flick response. I. 8-hydroxy-2-(di-n-propylamino) tetralin HBr-induced spontaneous tail-flicks in the rat as an in vivo model of 5-HT1A receptor-mediated activity.
    Millan MJ, Bervoets K, Colpaert FC.
    J Pharmacol Exp Ther; 1991 Mar; 256(3):973-82. PubMed ID: 1826033
    [Abstract] [Full Text] [Related]

  • 11. S 18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-yl methyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride.
    Millan MJ, Newman-Tancredi A, Brocco M, Gobert A, Lejeune F, Audinot V, Rivet JM, Schreiber R, Dekeyne A, Spedding M, Nicolas JP, Peglion JL.
    J Pharmacol Exp Ther; 1998 Oct; 287(1):167-86. PubMed ID: 9765336
    [Abstract] [Full Text] [Related]

  • 12. Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands.
    Gonzalez-Alvear GM, Werling LL.
    J Pharmacol Exp Ther; 1994 Oct; 271(1):212-9. PubMed ID: 7965717
    [Abstract] [Full Text] [Related]

  • 13. [3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
    Bonhaus DW, Loury DN, Jakeman LB, Hsu SA, To ZP, Leung E, Zeitung KD, Eglen RM, Wong EH.
    J Pharmacol Exp Ther; 1994 Oct; 271(1):484-93. PubMed ID: 7965749
    [Abstract] [Full Text] [Related]

  • 14. Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity.
    Seeger TF, Seymour PA, Schmidt AW, Zorn SH, Schulz DW, Lebel LA, McLean S, Guanowsky V, Howard HR, Lowe JA.
    J Pharmacol Exp Ther; 1995 Oct; 275(1):101-13. PubMed ID: 7562537
    [Abstract] [Full Text] [Related]

  • 15. EMD 57445, the selective sigma receptor ligand, has no effect on the 5-hydroxytryptamine system.
    Skuza G, Rogóz Z, Gołembiowska K.
    Pol J Pharmacol; 1997 Oct; 49(6):489-93. PubMed ID: 9566054
    [Abstract] [Full Text] [Related]

  • 16. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Berardi F, Colabufo NA, Giudice G, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1996 Jan 05; 39(1):176-82. PubMed ID: 8568804
    [Abstract] [Full Text] [Related]

  • 17. NPC 16377, a potent and selective sigma-ligand. I. Receptor binding, neurochemical and neuroendocrine profile.
    Karbon EW, Abreu ME, Erickson RH, Kaiser C, Natalie KJ, Clissold DB, Borosky S, Bailey M, Martin LA, Pontecorvo MJ.
    J Pharmacol Exp Ther; 1993 May 05; 265(2):866-75. PubMed ID: 8388461
    [Abstract] [Full Text] [Related]

  • 18. Novel potent sigma 1 ligands: N-[omega-(tetralin-1-yl)alkyl]piperidine derivatives.
    Berardi F, Giudice G, Perrone R, Tortorella V, Govoni S, Lucchi L.
    J Med Chem; 1996 Oct 11; 39(21):4255-60. PubMed ID: 8863803
    [Abstract] [Full Text] [Related]

  • 19. Novel piperidine sigma receptor ligands as potential antipsychotic drugs.
    Gilligan PJ, Cain GA, Christos TE, Cook L, Drummond S, Johnson AL, Kergaye AA, McElroy JF, Rohrbach KW, Schmidt WK.
    J Med Chem; 1992 Nov 13; 35(23):4344-61. PubMed ID: 1360026
    [Abstract] [Full Text] [Related]

  • 20. Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat.
    Lucki I, Nobler MS, Frazer A.
    J Pharmacol Exp Ther; 1984 Jan 13; 228(1):133-9. PubMed ID: 6694097
    [Abstract] [Full Text] [Related]

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