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4. Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background. Szántó S, Bárdos T, Szabó Z, David CS, Buzás EI, Mikecz K, Glant TT. Arthritis Rheum; 2004 Jun; 50(6):1984-95. PubMed ID: 15188376 [Abstract] [Full Text] [Related]
7. Immunity to the G1 globular domain of the cartilage proteoglycan aggrecan can induce inflammatory erosive polyarthritis and spondylitis in BALB/c mice but immunity to G1 is inhibited by covalently bound keratan sulfate in vitro and in vivo. Leroux JY, Guerassimov A, Cartman A, Delaunay N, Webber C, Rosenberg LC, Banerjee S, Poole AR. J Clin Invest; 1996 Feb 01; 97(3):621-32. PubMed ID: 8609216 [Abstract] [Full Text] [Related]
9. Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes. Zhang Y, Guerassimov A, Leroux JY, Cartman A, Webber C, Lalic R, de Miguel E, Rosenberg LC, Poole AR. J Clin Invest; 1998 Apr 15; 101(8):1678-86. PubMed ID: 9541498 [Abstract] [Full Text] [Related]
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16. Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage. Glant TT, Cs-Szabó G, Nagase H, Jacobs JJ, Mikecz K. Arthritis Rheum; 1998 Jun 15; 41(6):1007-18. PubMed ID: 9627010 [Abstract] [Full Text] [Related]