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Journal Abstract Search

189 related items for PubMed ID: 1381244

  • 1. Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (greater than 50 chromosomes) B-lineage acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J.
    Blood; 1992 Sep 01; 80(5):1316-23. PubMed ID: 1381244
    [Abstract] [Full Text] [Related]

  • 2. Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study.
    Whitehead VM, Vuchich MJ, Cooley LD, Lauer SJ, Mahoney DH, Shuster JJ, Payment C, Koch PA, Akabutu JJ, Bowen T, Kamen BA, Ravindranath Y, Emami A, Look AT, Beardsley GP, Pullen DJ, Camitta B.
    Leuk Lymphoma; 1998 Nov 01; 31(5-6):507-19. PubMed ID: 9922041
    [Abstract] [Full Text] [Related]

  • 3. The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Payment C, Cooley L, Lauer SJ, Mahoney DH, Shuster JJ, Vuchich MJ, Bernstein ML, Look AT, Pullen DJ, Camitta B.
    Leukemia; 2001 Jul 01; 15(7):1081-8. PubMed ID: 11455977
    [Abstract] [Full Text] [Related]

  • 4. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC, Yanishevski Y, Pui CH, Sandlund JT, Rubnitz J, Rivera GK, Ribeiro R, Evans WE, Relling MV.
    Cancer Chemother Pharmacol; 2002 Nov 01; 50(5):419-28. PubMed ID: 12439601
    [Abstract] [Full Text] [Related]

  • 5. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysis.
    Whitehead VM, Rosenblatt DS, Vuchich MJ, Shuster JJ, Witte A, Beaulieu D.
    Blood; 1990 Jul 01; 76(1):44-9. PubMed ID: 1694703
    [Abstract] [Full Text] [Related]

  • 6. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui CH, Relling MV, Evans WE.
    Blood; 1999 Mar 01; 93(5):1643-50. PubMed ID: 10029593
    [Abstract] [Full Text] [Related]

  • 7. Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.
    Kager L, Cheok M, Yang W, Zaza G, Cheng Q, Panetta JC, Pui CH, Downing JR, Relling MV, Evans WE.
    J Clin Invest; 2005 Jan 01; 115(1):110-7. PubMed ID: 15630450
    [Abstract] [Full Text] [Related]

  • 8. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
    Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE.
    Mol Pharmacol; 1997 Jul 01; 52(1):155-63. PubMed ID: 9224825
    [Abstract] [Full Text] [Related]

  • 9. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Shuster JJ, Vuchich MJ, Mahoney DH, Lauer SJ, Payment C, Koch PA, Cooley LD, Look AT, Pullen DJ, Camitta B.
    Leukemia; 2005 Apr 01; 19(4):533-6. PubMed ID: 15716987
    [Abstract] [Full Text] [Related]

  • 10. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE.
    J Clin Invest; 1994 Nov 01; 94(5):1996-2001. PubMed ID: 7525652
    [Abstract] [Full Text] [Related]

  • 11. Translocations involving chromosome 12p11-13, methotrexate metabolism, and outcome in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Whitehead VM, Vuchich MJ, Cooley L, Lauer SJ, Mahoney DH, Shuster JJ, Payment C, Bernstein ML, Akabutu JJ, Bowen T, Kamen BA, Watson MS, Look AT, Pullen DJ, Camitta B.
    Clin Cancer Res; 1998 Jan 01; 4(1):183-8. PubMed ID: 9516969
    [Abstract] [Full Text] [Related]

  • 12. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui CH, Evans WE.
    J Clin Invest; 1996 Jan 01; 97(1):73-80. PubMed ID: 8550853
    [Abstract] [Full Text] [Related]

  • 13. Time course of methotrexate polyglutamate formation and degradation in the pre-B-leukaemia cell line Nalm6 and in lymphoblasts from children with leukaemia.
    Buchholz B, Frei E, Eisenbarth J, Weigand M, Ludwig R.
    Eur J Cancer; 1996 Nov 01; 32A(12):2101-7. PubMed ID: 9014752
    [Abstract] [Full Text] [Related]

  • 14. Methotrexate polyglutamate synthesis in lymphoblasts from children with acute lymphoblastic leukemia.
    Whitehead VM, Rosenblatt DS, Vuchich MJ, Beaulieu D.
    Dev Pharmacol Ther; 1987 Nov 01; 10(6):443-8. PubMed ID: 2445535
    [Abstract] [Full Text] [Related]

  • 15. Comparative analysis of methotrexate polyglutamates in lymphoblast preparations from bone marrow and blood, and the contribution of residual red blood cells.
    Weigand M, Frei E, Graf N, Wiessler M.
    J Cancer Res Clin Oncol; 2000 Jul 01; 126(7):407-11. PubMed ID: 10929763
    [Abstract] [Full Text] [Related]

  • 16. Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo.
    Lopez-Lopez E, Autry RJ, Smith C, Yang W, Paugh SW, Panetta JC, Crews KR, Bonten EJ, Smart B, Pei D, McCorkle JR, Diouf B, Roberts KG, Shi L, Pounds S, Cheng C, Mullighan CG, Pui CH, Relling MV, Evans WE.
    J Clin Invest; 2020 Dec 01; 130(12):6600-6615. PubMed ID: 33164984
    [Abstract] [Full Text] [Related]

  • 17. Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate.
    Mantadakis E, Smith AK, Hynan L, Winick NJ, Kamen BA.
    J Pediatr Hematol Oncol; 2002 Nov 01; 24(8):636-42. PubMed ID: 12439035
    [Abstract] [Full Text] [Related]

  • 18. Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.
    Panetta JC, Sparreboom A, Pui CH, Relling MV, Evans WE.
    PLoS Comput Biol; 2010 Dec 02; 6(12):e1001019. PubMed ID: 21152005
    [Abstract] [Full Text] [Related]

  • 19. Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia.
    French D, Yang W, Cheng C, Raimondi SC, Mullighan CG, Downing JR, Evans WE, Pui CH, Relling MV.
    Blood; 2009 May 07; 113(19):4512-20. PubMed ID: 19066393
    [Abstract] [Full Text] [Related]

  • 20. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy.
    Nersting J, Nielsen SN, Grell K, Paerregaard M, Abrahamsson J, Lund B, Jonsson OG, Pruunsild K, Vaitkeviciene G, Kanerva J, Schmiegelow K, Nordic Society of Paediatric Haematology and Oncology (NOPHO).
    Cancer Chemother Pharmacol; 2019 Jan 07; 83(1):53-60. PubMed ID: 30324220
    [Abstract] [Full Text] [Related]

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