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176 related items for PubMed ID: 1394617

  • 1. Determination of the relative contributions of the diselenide and selenol forms of ebselen in the mechanism of its glutathione peroxidase-like activity.
    Morgenstern R, Cotgreave IA, Engman L.
    Chem Biol Interact; 1992 Sep 14; 84(1):77-84. PubMed ID: 1394617
    [Abstract] [Full Text] [Related]

  • 2. Characterisation and quantitation of a selenol intermediate in the reaction of ebselen with thiols.
    Cotgreave IA, Morgenstern R, Engman L, Ahokas J.
    Chem Biol Interact; 1992 Sep 14; 84(1):69-76. PubMed ID: 1394616
    [Abstract] [Full Text] [Related]

  • 3. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase.
    Zhao R, Holmgren A.
    J Biol Chem; 2002 Oct 18; 277(42):39456-62. PubMed ID: 12177067
    [Abstract] [Full Text] [Related]

  • 4. Modeling the reduction of hydrogen peroxide by glutathione peroxidase mimics.
    Pearson JK, Boyd RJ.
    J Phys Chem A; 2006 Jul 20; 110(28):8979-85. PubMed ID: 16836462
    [Abstract] [Full Text] [Related]

  • 5. Mechanism of the reaction of ebselen with endogenous thiols: dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen.
    Haenen GR, De Rooij BM, Vermeulen NP, Bast A.
    Mol Pharmacol; 1990 Mar 20; 37(3):412-22. PubMed ID: 2107391
    [Abstract] [Full Text] [Related]

  • 6. Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51).
    Maiorino M, Roveri A, Coassin M, Ursini F.
    Biochem Pharmacol; 1988 Jun 01; 37(11):2267-71. PubMed ID: 3377822
    [Abstract] [Full Text] [Related]

  • 7. Density functional theory study of the reaction mechanism and energetics of the reduction of hydrogen peroxide by ebselen, ebselen diselenide, and ebselen selenol.
    Pearson JK, Boyd RJ.
    J Phys Chem A; 2007 Apr 26; 111(16):3152-60. PubMed ID: 17407273
    [Abstract] [Full Text] [Related]

  • 8. Alpha-(phenylselenenyl)acetophenone derivatives with glutathione peroxidase-like activity. A comparison with ebselen.
    Cotgreave IA, Moldéus P, Brattsand R, Hallberg A, Andersson CM, Engman L.
    Biochem Pharmacol; 1992 Feb 18; 43(4):793-802. PubMed ID: 1540234
    [Abstract] [Full Text] [Related]

  • 9. Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions.
    Sarma BK, Mugesh G.
    J Am Chem Soc; 2005 Aug 17; 127(32):11477-85. PubMed ID: 16089478
    [Abstract] [Full Text] [Related]

  • 10. In vitro evaluation of glutathione peroxidase (GPx)-like activity and antioxidant properties of some Ebselen analogues.
    Mouithys-Mickalad Mareque A, Faez JM, Chistiaens L, Kohnen S, Deby C, Hoebeke M, Lamy M, Deby-Dupont G.
    Redox Rep; 2004 Aug 17; 9(2):81-7. PubMed ID: 15231062
    [Abstract] [Full Text] [Related]

  • 11. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant.
    Zhao R, Masayasu H, Holmgren A.
    Proc Natl Acad Sci U S A; 2002 Jun 25; 99(13):8579-84. PubMed ID: 12070343
    [Abstract] [Full Text] [Related]

  • 12. Ebselen, a selenoorganic compound as glutathione peroxidase mimic.
    Sies H.
    Free Radic Biol Med; 1993 Mar 25; 14(3):313-23. PubMed ID: 8458589
    [Abstract] [Full Text] [Related]

  • 13. An ebselen like catalyst with enhanced GPx activity via a selenol intermediate.
    Balkrishna SJ, Kumar S, Azad GK, Bhakuni BS, Panini P, Ahalawat N, Tomar RS, Detty MR, Kumar S.
    Org Biomol Chem; 2014 Feb 28; 12(8):1215-9. PubMed ID: 24448734
    [Abstract] [Full Text] [Related]

  • 14. The synthesis of glutathione peroxidase analogs.
    Spector A, Wilson SR, Zucker PA, Huang RR, Raghavan PR.
    Lens Eye Toxic Res; 1989 Feb 28; 6(4):773-80. PubMed ID: 2487281
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria.
    Filipovska A, Kelso GF, Brown SE, Beer SM, Smith RA, Murphy MP.
    J Biol Chem; 2005 Jun 24; 280(25):24113-26. PubMed ID: 15831495
    [Abstract] [Full Text] [Related]

  • 16. N-acetylcysteine and glutathione-dependent protective effect of PZ51 (Ebselen) against diquat-induced cytotoxicity in isolated hepatocytes.
    Cotgreave IA, Sandy MS, Berggren M, Moldéus PW, Smith MT.
    Biochem Pharmacol; 1987 Sep 15; 36(18):2899-904. PubMed ID: 3632716
    [Abstract] [Full Text] [Related]

  • 17.
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  • 18. Pyridoxine-derived organoselenium compounds with glutathione peroxidase-like and chain-breaking antioxidant activity.
    Singh VP, Poon JF, Butcher RJ, Engman L.
    Chemistry; 2014 Sep 22; 20(39):12563-71. PubMed ID: 25123932
    [Abstract] [Full Text] [Related]

  • 19. Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: a pathway for their neuroprotective effects.
    de Freitas AS, Rocha JB.
    Neurosci Lett; 2011 Sep 26; 503(1):1-5. PubMed ID: 21839146
    [Abstract] [Full Text] [Related]

  • 20. Ebselen, a selenium-containing redox drug, releases zinc from metallothionein.
    Jacob C, Maret W, Vallee BL.
    Biochem Biophys Res Commun; 1998 Jul 30; 248(3):569-73. PubMed ID: 9703967
    [Abstract] [Full Text] [Related]

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