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180 related items for PubMed ID: 1403804

  • 1. Mechanism for the hepatotoxicity of the antiandrogen, nilutamide. Evidence suggesting that redox cycling of this nitroaromatic drug leads to oxidative stress in isolated hepatocytes.
    Fau D, Berson A, Eugene D, Fromenty B, Fisch C, Pessayre D.
    J Pharmacol Exp Ther; 1992 Oct; 263(1):69-77. PubMed ID: 1403804
    [Abstract] [Full Text] [Related]

  • 2. Generation of free radicals during the reductive metabolism of the nitroaromatic compound, nilutamide.
    Berson A, Wolf C, Berger V, Fau D, Chachaty C, Fromenty B, Pessayre D.
    J Pharmacol Exp Ther; 1991 May; 257(2):714-9. PubMed ID: 1851835
    [Abstract] [Full Text] [Related]

  • 3. Inhibition by nilutamide of the mitochondrial respiratory chain and ATP formation. Possible contribution to the adverse effects of this antiandrogen.
    Berson A, Schmets L, Fisch C, Fau D, Wolf C, Fromenty B, Deschamps D, Pessayre D.
    J Pharmacol Exp Ther; 1994 Jul; 270(1):167-76. PubMed ID: 8035313
    [Abstract] [Full Text] [Related]

  • 4. Toxicity of the antiandrogen flutamide in isolated rat hepatocytes.
    Fau D, Eugene D, Berson A, Letteron P, Fromenty B, Fisch C, Pessayre D.
    J Pharmacol Exp Ther; 1994 Jun; 269(3):954-62. PubMed ID: 8014883
    [Abstract] [Full Text] [Related]

  • 5. Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug.
    Ask K, Dijols S, Giroud C, Casse L, Frapart YM, Sari MA, Kim KS, Stuehr DJ, Mansuy D, Camus P, Boucher JL.
    Chem Res Toxicol; 2003 Dec; 16(12):1547-54. PubMed ID: 14680368
    [Abstract] [Full Text] [Related]

  • 6. Generation of free radicals during the reductive metabolism of nilutamide by lung microsomes: possible role in the development of lung lesions in patients treated with this anti-androgen.
    Berger V, Berson A, Wolf C, Chachaty C, Fau D, Fromenty B, Pessayre D.
    Biochem Pharmacol; 1992 Feb 04; 43(3):654-7. PubMed ID: 1311586
    [Abstract] [Full Text] [Related]

  • 7. The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
    Carvalho M, Remião F, Milhazes N, Borges F, Fernandes E, Carvalho F, Bastos ML.
    Toxicology; 2004 Aug 05; 200(2-3):193-203. PubMed ID: 15212815
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of sulfite cytotoxicity in isolated rat hepatocytes.
    Niknahad H, O'Brien PJ.
    Chem Biol Interact; 2008 Aug 11; 174(3):147-54. PubMed ID: 18579106
    [Abstract] [Full Text] [Related]

  • 9. Cyclosporine A-induced oxidative stress in rat hepatocytes.
    Wolf A, Trendelenburg CF, Diez-Fernandez C, Prieto P, Houy S, Trommer WE, Cordier A.
    J Pharmacol Exp Ther; 1997 Mar 11; 280(3):1328-34. PubMed ID: 9067320
    [Abstract] [Full Text] [Related]

  • 10. Role of metabolism and oxidation-reduction cycling in the cytotoxicity of antitumor quinoneimines and quinonediimines.
    Powis G, Hodnett EM, Santone KS, See KL, Melder DC.
    Cancer Res; 1987 May 01; 47(9):2363-70. PubMed ID: 3032421
    [Abstract] [Full Text] [Related]

  • 11. Involvement of xanthine oxidase in oxidative stress and iron release during hyperthermic rat liver perfusion.
    Powers RH, Stadnicka A, Kalbfleish JH, Skibba JL.
    Cancer Res; 1992 Apr 01; 52(7):1699-703. PubMed ID: 1551099
    [Abstract] [Full Text] [Related]

  • 12. d-Amphetamine interaction with glutathione in freshly isolated rat hepatocytes.
    Carvalho F, Remião F, Amado F, Domingues P, Correia AJ, Bastos ML.
    Chem Res Toxicol; 1996 Sep 01; 9(6):1031-6. PubMed ID: 8870992
    [Abstract] [Full Text] [Related]

  • 13. Alkylation-induced oxidative cell injury of renal proximal tubular cells: involvement of glutathione redox-cycle inhibition.
    van de Water B, Zoeteweij JP, Nagelkerke JF.
    Arch Biochem Biophys; 1996 Mar 01; 327(1):71-80. PubMed ID: 8615698
    [Abstract] [Full Text] [Related]

  • 14. Effect of extracellular Ca++ omission on isolated hepatocytes. I. Induction of oxidative stress and cell injury.
    Thomas CE, Reed DJ.
    J Pharmacol Exp Ther; 1988 May 01; 245(2):493-500. PubMed ID: 3130475
    [Abstract] [Full Text] [Related]

  • 15. Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
    Silva JM, Rao DN, O'Brien PJ.
    Cancer Res; 1992 Jun 01; 52(11):3015-21. PubMed ID: 1375532
    [Abstract] [Full Text] [Related]

  • 16. Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: role of mitochondrial permeability transition and metabolic activation.
    Berson A, Descatoire V, Sutton A, Fau D, Maulny B, Vadrot N, Feldmann G, Berthon B, Tordjmann T, Pessayre D.
    J Pharmacol Exp Ther; 2001 Nov 01; 299(2):793-800. PubMed ID: 11602696
    [Abstract] [Full Text] [Related]

  • 17. Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats.
    Rikans LE, Cai Y.
    Toxicol Appl Pharmacol; 1993 Feb 01; 118(2):263-70. PubMed ID: 8382845
    [Abstract] [Full Text] [Related]

  • 18. Oxygen-dependent hepatotoxicity due to doxorubicin: role of reducing equivalent supply in perfused rat liver.
    Ganey PE, Kauffman FC, Thurman RG.
    Mol Pharmacol; 1988 Nov 01; 34(5):695-701. PubMed ID: 3193959
    [Abstract] [Full Text] [Related]

  • 19. Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes.
    Aly HA, Domènech O.
    Toxicology; 2009 Aug 21; 262(3):175-83. PubMed ID: 19486918
    [Abstract] [Full Text] [Related]

  • 20. Effect of extracellular Ca++ omission on isolated hepatocytes. II. Loss of mitochondrial membrane potential and protection by inhibitors of uniport Ca++ transduction.
    Thomas CE, Reed DJ.
    J Pharmacol Exp Ther; 1988 May 21; 245(2):501-7. PubMed ID: 2452872
    [Abstract] [Full Text] [Related]

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