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117 related items for PubMed ID: 1423294

  • 1. Expression of the endogenous O6-methylguanine-DNA-methyltransferase protects Chinese hamster ovary cells from spontaneous G:C to A:T transitions.
    Aquilina G, Biondo R, Dogliotti E, Meuth M, Bignami M.
    Cancer Res; 1992 Dec 01; 52(23):6471-5. PubMed ID: 1423294
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  • 2. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL, Hsieh FP, Lee PC, Tseng HJ.
    Cancer Res; 1994 Jul 15; 54(14):3857-63. PubMed ID: 8033107
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  • 3. Specificity of bischloroethylnitrosourea-induced mutation in a Chinese hamster ovary cell line transformed to express human O6-alkylguanine-DNA alkyltransferase.
    Minnick DT, Gerson SL, Dumenco LL, Veigl ML, Sedwick WD.
    Cancer Res; 1993 Mar 01; 53(5):997-1003. PubMed ID: 8439973
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  • 4. Mutational specificity of 1,3-bis-(2-chloroethyl)-1-nitrosourea in a Chinese hamster ovary cell line.
    Minnick DT, Veigl ML, Sedwick WD.
    Cancer Res; 1992 Sep 01; 52(17):4688-95. PubMed ID: 1511435
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  • 5. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J, Kaina B.
    Oncogene; 1996 Nov 07; 13(9):1927-35. PubMed ID: 8934539
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  • 6. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN, Chan CL, Eastman A, Bresnick E.
    Cancer Res; 1992 Jan 01; 52(1):32-5. PubMed ID: 1727384
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  • 7. Intrachromosomal probes for mutagenesis by alkylated DNA bases replicated in mammalian cells: a comparison of the mutagenicities of O4-methylthymine and O6-methylguanine in cells with different DNA repair backgrounds.
    Altshuler KB, Hodes CS, Essigmann JM.
    Chem Res Toxicol; 1996 Sep 01; 9(6):980-7. PubMed ID: 8870985
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  • 11. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
    Esteller M, Risques RA, Toyota M, Capella G, Moreno V, Peinado MA, Baylin SB, Herman JG.
    Cancer Res; 2001 Jun 15; 61(12):4689-92. PubMed ID: 11406538
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  • 12. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, Watkins DN, Issa JP, Sidransky D, Baylin SB, Herman JG.
    Cancer Res; 2000 May 01; 60(9):2368-71. PubMed ID: 10811111
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  • 13. Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
    Allay E, Veigl M, Gerson SL.
    Oncogene; 1999 Jun 24; 18(25):3783-7. PubMed ID: 10391687
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  • 14. Enhancement of O6-methylguanine-DNA-methyltransferase activity induced by various treatments in mammalian cells.
    Lefebvre P, Laval F.
    Cancer Res; 1986 Nov 24; 46(11):5701-5. PubMed ID: 2428481
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  • 15. Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.
    Hazra TK, Roy R, Biswas T, Grabowski DT, Pegg AE, Mitra S.
    Biochemistry; 1997 May 13; 36(19):5769-76. PubMed ID: 9153417
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  • 16. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent.
    Ochs K, Kaina B.
    Cancer Res; 2000 Oct 15; 60(20):5815-24. PubMed ID: 11059778
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  • 19. Mutagenicity and mutational spectrum of N-methyl-N'-nitro-N-nitrosoguanidine in the hprt gene in G1-S and late S phase of diploid human fibroblasts.
    Yang JL, Lin JG, Hu MC, Wu CW.
    Cancer Res; 1993 Jun 15; 53(12):2865-73. PubMed ID: 8504428
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  • 20. Inactivation of O6-methylguanine-DNA methyltransferase in soft tissue sarcomas: association with K-ras mutations.
    Kim JI, Suh JT, Choi KU, Kang HJ, Shin DH, Lee IS, Moon TY, Kim WT.
    Hum Pathol; 2009 Jul 15; 40(7):934-41. PubMed ID: 19356788
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