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433 related items for PubMed ID: 1428403

  • 1. Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells.
    Rodrigues ML, Shalaby MR, Werther W, Presta L, Carter P.
    Int J Cancer Suppl; 1992; 7():45-50. PubMed ID: 1428403
    [Abstract] [Full Text] [Related]

  • 2. Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation.
    Zhu Z, Carter P.
    J Immunol; 1995 Aug 15; 155(4):1903-10. PubMed ID: 7636241
    [Abstract] [Full Text] [Related]

  • 3. Engineering Fab' fragments for efficient F(ab)2 formation in Escherichia coli and for improved in vivo stability.
    Rodrigues ML, Snedecor B, Chen C, Wong WL, Garg S, Blank GS, Maneval D, Carter P.
    J Immunol; 1993 Dec 15; 151(12):6954-61. PubMed ID: 7903100
    [Abstract] [Full Text] [Related]

  • 4. Trispecific F(ab')3 derivatives that use cooperative signaling via the TCR/CD3 complex and CD2 to activate and redirect resting cytotoxic T cells.
    Tutt A, Stevenson GT, Glennie MJ.
    J Immunol; 1991 Jul 01; 147(1):60-9. PubMed ID: 1675655
    [Abstract] [Full Text] [Related]

  • 5. Engineering high affinity humanized anti-p185HER2/anti-CD3 bispecific F(ab')2 for efficient lysis of p185HER2 overexpressing tumor cells.
    Zhu Z, Lewis GD, Carter P.
    Int J Cancer; 1995 Jul 28; 62(3):319-24. PubMed ID: 7628874
    [Abstract] [Full Text] [Related]

  • 6. The role of T cell activation in anti-CD3 x antitumor bispecific antibody therapy.
    Weiner GJ, Kostelny SA, Hillstrom JR, Cole MS, Link BK, Wang SL, Tso JY.
    J Immunol; 1994 Mar 01; 152(5):2385-92. PubMed ID: 8133049
    [Abstract] [Full Text] [Related]

  • 7. [High level expression of chimeric antibody fragment F(ab')2 directed against CD20 in Escherichia coli].
    Xiong DS, Zheng MJ, Liu YX, Xu YF, Wang JH, Yang CZ.
    Sheng Wu Gong Cheng Xue Bao; 2004 Sep 01; 20(5):673-8. PubMed ID: 15973988
    [Abstract] [Full Text] [Related]

  • 8. Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine {lambda} to human {lambda} or {kappa} light chains.
    Schlapschy M, Fogarasi M, Gruber H, Gresch O, Schäfer C, Aguib Y, Skerra A.
    Protein Eng Des Sel; 2009 Mar 01; 22(3):175-88. PubMed ID: 19022801
    [Abstract] [Full Text] [Related]

  • 9. Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation.
    Ledbetter JA, June CH, Martin PJ, Spooner CE, Hansen JA, Meier KE.
    J Immunol; 1986 Jun 01; 136(11):3945-52. PubMed ID: 3084650
    [Abstract] [Full Text] [Related]

  • 10. An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.
    Alegre ML, Tso JY, Sattar HA, Smith J, Desalle F, Cole M, Bluestone JA.
    J Immunol; 1995 Aug 01; 155(3):1544-55. PubMed ID: 7636216
    [Abstract] [Full Text] [Related]

  • 11. Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene.
    Shalaby MR, Shepard HM, Presta L, Rodrigues ML, Beverley PC, Feldmann M, Carter P.
    J Exp Med; 1992 Jan 01; 175(1):217-25. PubMed ID: 1346155
    [Abstract] [Full Text] [Related]

  • 12. Anti-CD3 x anti-tumor F(ab')2 bifunctional antibody activates and retargets tumor-infiltrating lymphocytes.
    Chapoval AI, Nelson H, Thibault C.
    J Immunol; 1995 Aug 01; 155(3):1296-303. PubMed ID: 7636196
    [Abstract] [Full Text] [Related]

  • 13. Formation of a bispecific antibody by the use of leucine zippers.
    Kostelny SA, Cole MS, Tso JY.
    J Immunol; 1992 Mar 01; 148(5):1547-53. PubMed ID: 1531669
    [Abstract] [Full Text] [Related]

  • 14. Differential T cell hyporesponsiveness induced by in vivo administration of intact or F(ab')2 fragments of anti-CD3 monoclonal antibody. F(ab')2 fragments induce a selective T helper dysfunction.
    Hirsch R, Archibald J, Gress RE.
    J Immunol; 1991 Oct 01; 147(7):2088-93. PubMed ID: 1833451
    [Abstract] [Full Text] [Related]

  • 15. Bispecific F (ab')2 monomer prepared with anti-CD3 and anti-tumor monoclonal antibodies is most potent in induction of cytolysis of human T cells.
    Nitta T, Yagita H, Azuma T, Sato K, Okumura K.
    Eur J Immunol; 1989 Aug 01; 19(8):1437-41. PubMed ID: 2528460
    [Abstract] [Full Text] [Related]

  • 16. Humanized OKT3 antibodies: successful transfer of immune modulating properties and idiotype expression.
    Woodle ES, Thistlethwaite JR, Jolliffe LK, Zivin RA, Collins A, Adair JR, Bodmer M, Athwal D, Alegre ML, Bluestone JA.
    J Immunol; 1992 May 01; 148(9):2756-63. PubMed ID: 1533410
    [Abstract] [Full Text] [Related]

  • 17. Functional humanization of an anti-CD30 Fab fragment for the immunotherapy of Hodgkin's lymphoma using an in vitro evolution approach.
    Schlapschy M, Gruber H, Gresch O, Schäfer C, Renner C, Pfreundschuh M, Skerra A.
    Protein Eng Des Sel; 2004 Dec 01; 17(12):847-60. PubMed ID: 15708864
    [Abstract] [Full Text] [Related]

  • 18. CD3 directed bispecific antibodies induce increased lymphocyte-endothelial cell interactions in vitro.
    Molema G, Tervaert JW, Kroesen BJ, Helfrich W, Meijer DK, de Leij LF.
    Br J Cancer; 2000 Jan 01; 82(2):472-9. PubMed ID: 10646907
    [Abstract] [Full Text] [Related]

  • 19. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC, Shan L, Goldsteen BZ, Guddat LW, Thakur A, Landolfi NF, Co MS, Vasquez M, Queen C, Ramsland PA, Edmundson AB.
    J Mol Recognit; 1999 Jan 01; 12(1):19-32. PubMed ID: 10398393
    [Abstract] [Full Text] [Related]

  • 20. Humanization of the murine anti-human CD3 monoclonal antibody OKT3.
    Adair JR, Athwal DS, Bodmer MW, Bright SM, Collins AM, Pulito VL, Rao PE, Reedman R, Rothermel AL, Xu D.
    Hum Antibodies Hybridomas; 1994 Jan 01; 5(1-2):41-7. PubMed ID: 7858182
    [Abstract] [Full Text] [Related]

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