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300 related items for PubMed ID: 1438284

  • 1. Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis.
    Harel M, Sussman JL, Krejci E, Bon S, Chanal P, Massoulié J, Silman I.
    Proc Natl Acad Sci U S A; 1992 Nov 15; 89(22):10827-31. PubMed ID: 1438284
    [Abstract] [Full Text] [Related]

  • 2. Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
    Kaplan D, Ordentlich A, Barak D, Ariel N, Kronman C, Velan B, Shafferman A.
    Biochemistry; 2001 Jun 26; 40(25):7433-45. PubMed ID: 11412096
    [Abstract] [Full Text] [Related]

  • 3. Determinants of substrate specificity of a second non-neuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis.
    Hussein AS, Smith AM, Chacón MR, Selkirk ME.
    Eur J Biochem; 2000 Apr 26; 267(8):2276-82. PubMed ID: 10759851
    [Abstract] [Full Text] [Related]

  • 4. Asp7O in the peripheral anionic site of human butyrylcholinesterase.
    Masson P, Froment MT, Bartels CF, Lockridge O.
    Eur J Biochem; 1996 Jan 15; 235(1-2):36-48. PubMed ID: 8631355
    [Abstract] [Full Text] [Related]

  • 5. Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure.
    Soreq H, Ben-Aziz R, Prody CA, Seidman S, Gnatt A, Neville L, Lieman-Hurwitz J, Lev-Lehman E, Ginzberg D, Lipidot-Lifson Y.
    Proc Natl Acad Sci U S A; 1990 Dec 15; 87(24):9688-92. PubMed ID: 2263619
    [Abstract] [Full Text] [Related]

  • 6. Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity.
    Vellom DC, Radić Z, Li Y, Pickering NA, Camp S, Taylor P.
    Biochemistry; 1993 Jan 12; 32(1):12-7. PubMed ID: 8418833
    [Abstract] [Full Text] [Related]

  • 7. Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.
    Ordentlich A, Barak D, Kronman C, Flashner Y, Leitner M, Segall Y, Ariel N, Cohen S, Velan B, Shafferman A.
    J Biol Chem; 1993 Aug 15; 268(23):17083-95. PubMed ID: 8349597
    [Abstract] [Full Text] [Related]

  • 8. Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors.
    Weiner L, Shnyrov VL, Konstantinovskii L, Roth E, Ashani Y, Silman I.
    Biochemistry; 2009 Jan 27; 48(3):563-74. PubMed ID: 19115961
    [Abstract] [Full Text] [Related]

  • 9. Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase.
    Saxena A, Redman AM, Jiang X, Lockridge O, Doctor BP.
    Biochemistry; 1997 Dec 02; 36(48):14642-51. PubMed ID: 9398183
    [Abstract] [Full Text] [Related]

  • 10. Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.
    Komloova M, Musilek K, Horova A, Holas O, Dohnal V, Gunn-Moore F, Kuca K.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2505-9. PubMed ID: 21397501
    [Abstract] [Full Text] [Related]

  • 11. Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis.
    Loewenstein-Lichtenstein Y, Glick D, Gluzman N, Sternfeld M, Zakut H, Soreq H.
    Mol Pharmacol; 1996 Dec 15; 50(6):1423-31. PubMed ID: 8967962
    [Abstract] [Full Text] [Related]

  • 12. Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues.
    Prody CA, Zevin-Sonkin D, Gnatt A, Goldberg O, Soreq H.
    Proc Natl Acad Sci U S A; 1987 Jun 15; 84(11):3555-9. PubMed ID: 3035536
    [Abstract] [Full Text] [Related]

  • 13. Anionic subsites of the catalytic center of acetylcholinesterase from Torpedo and from cobra venom.
    Kreienkamp HJ, Weise C, Raba R, Aaviksaar A, Hucho F.
    Proc Natl Acad Sci U S A; 1991 Jul 15; 88(14):6117-21. PubMed ID: 2068091
    [Abstract] [Full Text] [Related]

  • 14. Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase.
    Felder CE, Harel M, Silman I, Sussman JL.
    Acta Crystallogr D Biol Crystallogr; 2002 Oct 15; 58(Pt 10 Pt 2):1765-71. PubMed ID: 12351819
    [Abstract] [Full Text] [Related]

  • 15. Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
    Saxena A, Fedorko JM, Vinayaka CR, Medhekar R, Radić Z, Taylor P, Lockridge O, Doctor BP.
    Eur J Biochem; 2003 Nov 15; 270(22):4447-58. PubMed ID: 14622273
    [Abstract] [Full Text] [Related]

  • 16. Spatiotemporal relationship of embryonic cholinesterases with cell proliferation in chicken brain and eye.
    Layer PG, Sporns O.
    Proc Natl Acad Sci U S A; 1987 Jan 15; 84(1):284-8. PubMed ID: 3467355
    [Abstract] [Full Text] [Related]

  • 17. Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.
    Komloova M, Horova A, Hrabinova M, Jun D, Dolezal M, Vinsova J, Kuca K, Musilek K.
    Bioorg Med Chem Lett; 2013 Dec 15; 23(24):6663-6. PubMed ID: 24220173
    [Abstract] [Full Text] [Related]

  • 18. Two cholinesterase activities and genes are present in amphioxus.
    Sutherland D, McClellan JS, Milner D, Soong W, Axon N, Sanders M, Hester A, Kao YH, Poczatek T, Routt S, Pezzementi L.
    J Exp Zool; 1997 Feb 15; 277(3):213-29. PubMed ID: 9062997
    [Abstract] [Full Text] [Related]

  • 19. Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase.
    Eichler J, Anselment A, Sussman JL, Massoulié J, Silman I.
    Mol Pharmacol; 1994 Feb 15; 45(2):335-40. PubMed ID: 8114681
    [Abstract] [Full Text] [Related]

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