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Journal Abstract Search


158 related items for PubMed ID: 1445905

  • 21.
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  • 22. Thrombin-specific inhibition by and slow cleavage of hirulog-1.
    Witting JI, Bourdon P, Brezniak DV, Maraganore JM, Fenton JW.
    Biochem J; 1992 May 01; 283 ( Pt 3)(Pt 3):737-43. PubMed ID: 1290488
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  • 26. Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.
    Krishnan R, Mochalkin I, Arni R, Tulinsky A.
    Acta Crystallogr D Biol Crystallogr; 2000 Mar 01; 56(Pt 3):294-303. PubMed ID: 10713516
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  • 27. Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues.
    Martin PD, Malkowski MG, DiMaio J, Konishi Y, Ni F, Edwards BF.
    Biochemistry; 1996 Oct 08; 35(40):13030-9. PubMed ID: 8855938
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  • 28. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
    Bode W, Turk D, Karshikov A.
    Protein Sci; 1992 Apr 08; 1(4):426-71. PubMed ID: 1304349
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  • 29. Crystallographic structure of a peptidyl keto acid inhibitor and human alpha-thrombin.
    Håkansson K, Tulinsky A, Abelman MM, Miller TA, Vlasuk GP, Bergum PW, Lim-Wilby MS, Brunck TK.
    Bioorg Med Chem; 1995 Aug 08; 3(8):1009-17. PubMed ID: 7582975
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  • 30. Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of alpha-thrombin.
    Ofosu FA, Fenton JW, Maraganore J, Blajchman MA, Yang X, Smith L, Anvari N, Buchanan MR, Hirsh J.
    Biochem J; 1992 May 01; 283 ( Pt 3)(Pt 3):893-7. PubMed ID: 1590777
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  • 31. Crystallographic structure of human gamma-thrombin.
    Rydel TJ, Yin M, Padmanabhan KP, Blankenship DT, Cardin AD, Correa PE, Fenton JW, Tulinsky A.
    J Biol Chem; 1994 Sep 02; 269(35):22000-6. PubMed ID: 8071320
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  • 32. The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage.
    Friedrich R, Steinmetzer T, Huber R, Stürzebecher J, Bode W.
    J Mol Biol; 2002 Mar 01; 316(4):869-74. PubMed ID: 11884127
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  • 33. The effect of antithrombin III-independent thrombin inhibitors and heparin on fibrin accretion onto fibrin-coated polyethylene.
    Rubens FD, Weitz JI, Brash JL, Kinlough-Rathbone RL.
    Thromb Haemost; 1993 Feb 01; 69(2):130-4. PubMed ID: 8456425
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  • 34. Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin.
    Tabernero L, Chang CY, Ohringer SL, Lau WF, Iwanowicz EJ, Han WC, Wang TC, Seiler SM, Roberts DG, Sack JS.
    J Mol Biol; 1995 Feb 10; 246(1):14-20. PubMed ID: 7853394
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  • 35. Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin.
    Rehse PH, Steinmetzer T, Li Y, Konishi Y, Cygler M.
    Biochemistry; 1995 Sep 12; 34(36):11537-44. PubMed ID: 7547884
    [Abstract] [Full Text] [Related]

  • 36. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W.
    J Mol Biol; 2001 Apr 13; 307(5):1451-86. PubMed ID: 11292354
    [Abstract] [Full Text] [Related]

  • 37. Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.
    Krishnan R, Sadler JE, Tulinsky A.
    Acta Crystallogr D Biol Crystallogr; 2000 Apr 13; 56(Pt 4):406-10. PubMed ID: 10739913
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  • 38. Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
    De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V.
    Protein Sci; 1998 Feb 13; 7(2):243-53. PubMed ID: 9521099
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  • 39. Structure-function relationships of hirulog peptide interactions with thrombin.
    Bourdon P, Jablonski JA, Chao BH, Maraganore JM.
    FEBS Lett; 1991 Dec 09; 294(3):163-6. PubMed ID: 1756854
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  • 40. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M, Matsuura Y, Sakakibara S, Katsube Y.
    Biochemistry; 1996 Sep 10; 35(36):11570-6. PubMed ID: 8794736
    [Abstract] [Full Text] [Related]


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