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Journal Abstract Search

123 related items for PubMed ID: 1445994

  • 1. Evaluation of some N-acyl analogues of 3,5-bis(arylidene)-4-piperidones for cytotoxic activity.
    Dimmock JR, Arora VK, Duffy MJ, Reid RS, Allen TM, Kao GY.
    Drug Des Discov; 1992 Jul; 8(4):291-9. PubMed ID: 1445994
    [Abstract] [Full Text] [Related]

  • 2. Cytotoxic evaluation of some N-acyl and N-acyloxy analogues of 3,5-bis(arylidene)-4-piperidones.
    Dimmock JR, Arora VK, Chen M, Allen TM, Kao GY.
    Drug Des Discov; 1994 Jul; 12(1):19-28. PubMed ID: 7578805
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.
    Das U, Alcorn J, Shrivastav A, Sharma RK, De Clercq E, Balzarini J, Dimmock JR.
    Eur J Med Chem; 2007 Jan; 42(1):71-80. PubMed ID: 16996657
    [Abstract] [Full Text] [Related]

  • 4. E,E,E-1-(4-Arylamino-4-oxo-2-butenoyl)-3,5-bis(arylidene)-4-piperidones: a topographical study of some novel potent cytotoxins.
    Jha A, Mukherjee C, Prasad AK, Parmar VS, Clercq ED, Balzarini J, Stables JP, Manavathu EK, Shrivastav A, Sharma RK, Nienaber KH, Zello GA, Dimmock JR.
    Bioorg Med Chem; 2007 Sep 01; 15(17):5854-65. PubMed ID: 17562365
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and bioevaluation of novel N-substituted-3,5-bis(arylidene)-4-piperidone derivatives as cytotoxic and antitumor agents with fluorescent properties.
    Sun J, Zhang S, Yu C, Hou G, Zhang X, Li K, Zhao F.
    Chem Biol Drug Des; 2014 Apr 01; 83(4):392-400. PubMed ID: 24148151
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and bioevaluation of novel maleamic amino acid ester conjugates of 3,5-bisarylmethylene-4-piperidones as cytostatic agents.
    Youssef D, Potter E, Jha M, De Clercq E, Balzarini J, Stables JP, Jha A.
    Bioorg Med Chem Lett; 2009 Nov 15; 19(22):6364-7. PubMed ID: 19819135
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.
    Kálai T, Kuppusamy ML, Balog M, Selvendiran K, Rivera BK, Kuppusamy P, Hideg K.
    J Med Chem; 2011 Aug 11; 54(15):5414-21. PubMed ID: 21702507
    [Abstract] [Full Text] [Related]

  • 8. 3,5-Bis-arylidene-1-methyl-4-piperidone methohalides and related compounds with activity against L 1210 cells and DNA binding properties.
    Dimmock JR, Arora VK, Semple HA, Lee JS, Allen TM, Kao GY.
    Pharmazie; 1992 Apr 11; 47(4):246-8. PubMed ID: 1518879
    [Abstract] [Full Text] [Related]

  • 9. Novel 3,5-bis(arylidene)-4-piperidone dimers: potent cytotoxins against colon cancer cells.
    Das S, Das U, Michel D, Gorecki DK, Dimmock JR.
    Eur J Med Chem; 2013 Jun 11; 64():321-8. PubMed ID: 23644215
    [Abstract] [Full Text] [Related]

  • 10. Cytotoxic activities of Mannich bases of chalcones and related compounds.
    Dimmock JR, Kandepu NM, Hetherington M, Quail JW, Pugazhenthi U, Sudom AM, Chamankhah M, Rose P, Pass E, Allen TM, Halleran S, Szydlowski J, Mutus B, Tannous M, Manavathu EK, Myers TG, De Clercq E, Balzarini J.
    J Med Chem; 1998 Mar 26; 41(7):1014-26. PubMed ID: 9544201
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and potent antileukemic activities of 10-benzyl-9(10H)-acridinones.
    Gao C, Jiang Y, Tan C, Zu X, Liu H, Cao D.
    Bioorg Med Chem; 2008 Sep 15; 16(18):8670-5. PubMed ID: 18713666
    [Abstract] [Full Text] [Related]

  • 12. (R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
    Kirshenbaum MR, Chen SF, Behrens CH, Papp LM, Stafford MM, Sun JH, Behrens DL, Fredericks JR, Polkus ST, Sipple P.
    Cancer Res; 1994 Apr 15; 54(8):2199-206. PubMed ID: 8174127
    [Abstract] [Full Text] [Related]

  • 13. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
    Palmer BD, Wilson WR, Anderson RF, Boyd M, Denny WA.
    J Med Chem; 1996 Jun 21; 39(13):2518-28. PubMed ID: 8691449
    [Abstract] [Full Text] [Related]

  • 14. Anti-tumor effect of dithiole compounds.
    Yoshida E, Fukami T, Takamiya K, Okura A.
    Anticancer Drug Des; 1988 Aug 21; 3(2):129-32. PubMed ID: 3408549
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, characterization and structure-activity relationship of novel N-phosphorylated E,E-3,5-bis(thienylidene)piperid-4-ones.
    Makarov MV, Leonova ES, Rybalkina EY, Tongwa P, Khrustalev VN, Timofeeva TV, Odinets IL.
    Eur J Med Chem; 2010 Mar 21; 45(3):992-1000. PubMed ID: 19969398
    [Abstract] [Full Text] [Related]

  • 16. Constrained derivatives of stylostatin 1. 1. Synthesis and biological evaluation as potential anticancer agents.
    Forns P, Piró J, Cuevas C, García M, Rubiralta M, Giralt E, Diez A.
    J Med Chem; 2003 Dec 18; 46(26):5825-33. PubMed ID: 14667235
    [Abstract] [Full Text] [Related]

  • 17. Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells.
    Bergeron RJ, Hawthorne TR, Vinson JR, Beck DE, Ingeno MJ.
    Cancer Res; 1989 Jun 01; 49(11):2959-64. PubMed ID: 2720656
    [Abstract] [Full Text] [Related]

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  • 20. Synthesis and cytotoxic activities of the amine-exchange products of 2-dimethylaminomethyl-5-(E)-substituted arylidene cyclopentanones with anilines: 2-arylaminomethyl-5-(E)-arylidene cyclopentanones.
    Chen H, Ji Z, Wong LK, Siuda JF, Narayanan VL.
    Drug Des Discov; 1996 Mar 01; 14(1):43-52. PubMed ID: 8854044
    [Abstract] [Full Text] [Related]

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