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158 related items for PubMed ID: 1446008

  • 1. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone pulmonary metabolism and tumorigenicity in mice by analogues of the investigational chemotherapeutic drug 4-ipomeanol.
    Lin JM, Desai DH, Morse MA, Amin S, Hecht SS.
    Chem Res Toxicol; 1992; 5(5):674-9. PubMed ID: 1446008
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and bioassay of 4-ipomeanol analogs as potential chemopreventive agents against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced tumorigenicity in A/J mice.
    Desai D, Chang L, Amin S.
    Cancer Lett; 1996 Nov 29; 108(2):263-70. PubMed ID: 8973604
    [Abstract] [Full Text] [Related]

  • 3. Ipomeanol analogs as chemopreventive agents: effect on the in vitro metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Desai D, Nunes M, Chang L, Lin JM, Jiao D, Amin S.
    Cancer Lett; 1995 Nov 06; 97(2):155-62. PubMed ID: 7497457
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in human hepatic microsomes by ipomeanol analogs--an exploratory study.
    Nunes MG, Desai D, Koehl W, Spratt TE, Guengerich FP, Amin S.
    Cancer Lett; 1998 Jul 17; 129(2):131-8. PubMed ID: 9719453
    [Abstract] [Full Text] [Related]

  • 5. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 6. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P, Kenney PM, Hochalter JB, Wang M, Hecht SS.
    Carcinogenesis; 1999 Aug 15; 20(8):1577-82. PubMed ID: 10426810
    [Abstract] [Full Text] [Related]

  • 7. Chemopreventive efficacy of suberoylanilide hydroxamic acid (SAHA) against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in female A/J mice.
    Desai D, Das A, Cohen L, el-Bayoumy K, Amin S.
    Anticancer Res; 2003 Aug 15; 23(1A):499-503. PubMed ID: 12680257
    [Abstract] [Full Text] [Related]

  • 8. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR, McIntee EJ, Kenney PM, Upadhyaya P, Peterson LA, Hecht SS.
    Chem Res Toxicol; 2003 Jun 15; 16(6):794-806. PubMed ID: 12807363
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A/J mouse lung.
    Hong JY, Wang ZY, Smith TJ, Zhou S, Shi S, Pan J, Yang CS.
    Carcinogenesis; 1992 May 15; 13(5):901-4. PubMed ID: 1587006
    [Abstract] [Full Text] [Related]

  • 10. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
    Richter E, Engl J, Friesenegger S, Tricker AR.
    Chem Res Toxicol; 2009 Jun 15; 22(6):1008-17. PubMed ID: 19408892
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of NNK-induced lung tumorigenesis by modulators of NNK activation.
    Morse MA.
    Exp Lung Res; 1998 Jun 15; 24(4):595-604. PubMed ID: 9659585
    [Abstract] [Full Text] [Related]

  • 12. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ, Guo Z, Gonzalez FJ, Guengerich FP, Stoner GD, Yang CS.
    Cancer Res; 1992 Apr 01; 52(7):1757-63. PubMed ID: 1312898
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
    Smith TJ, Guo ZY, Thomas PE, Chung FL, Morse MA, Elkind K, Yang CS.
    Cancer Res; 1990 Nov 01; 50(21):6817-22. PubMed ID: 2208146
    [Abstract] [Full Text] [Related]

  • 14. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Smith TJ, Liao AM, Liu Y, Jones AB, Anderson LM, Yang CS.
    Carcinogenesis; 1997 Aug 01; 18(8):1577-84. PubMed ID: 9276633
    [Abstract] [Full Text] [Related]

  • 15. Quantitation of microsomal alpha-hydroxylation of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Peterson LA, Mathew R, Hecht SS.
    Cancer Res; 1991 Oct 15; 51(20):5495-500. PubMed ID: 1913670
    [Abstract] [Full Text] [Related]

  • 16. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
    Guo Z, Smith TJ, Thomas PE, Yang CS.
    Arch Biochem Biophys; 1992 Oct 15; 298(1):279-86. PubMed ID: 1524438
    [Abstract] [Full Text] [Related]

  • 17. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA, LaGreca SD, Amin SG, Chung FL.
    Cancer Res; 1990 May 01; 50(9):2613-7. PubMed ID: 2328487
    [Abstract] [Full Text] [Related]

  • 18. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
    Maser E.
    Cancer Res; 1998 Jul 15; 58(14):2996-3003. PubMed ID: 9679962
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by dietary benzaldehydes.
    Morse MA, Kresty LA, Toburen AL.
    Cancer Lett; 1995 Nov 06; 97(2):255-61. PubMed ID: 7497471
    [Abstract] [Full Text] [Related]

  • 20. Effect of tobacco smoke condensate on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by adult and fetal hamster microsomes.
    Jorquera R, Castonguay A, Schuller HM.
    Drug Metab Dispos; 1993 Nov 06; 21(2):318-24. PubMed ID: 8097703
    [Abstract] [Full Text] [Related]

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