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158 related items for PubMed ID: 1446008

  • 21. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Collazo NR, Sultatos LG.
    Biochem Pharmacol; 1995 Nov 27; 50(11):1933-41. PubMed ID: 8615875
    [Abstract] [Full Text] [Related]

  • 22. Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398.
    Rioux N, Castonguay A.
    Cancer Res; 1998 Dec 01; 58(23):5354-60. PubMed ID: 9850065
    [Abstract] [Full Text] [Related]

  • 23. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ, Stoner GD, Yang CS.
    Cancer Res; 1995 Dec 01; 55(23):5566-73. PubMed ID: 7585636
    [Abstract] [Full Text] [Related]

  • 24. Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.
    Guo Z, Smith TJ, Wang E, Eklind KI, Chung FL, Yang CS.
    Carcinogenesis; 1993 Jun 01; 14(6):1167-73. PubMed ID: 8508504
    [Abstract] [Full Text] [Related]

  • 25. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Schrader E, Hirsch-Ernst KI, Richter E, Foth H.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar 01; 357(3):336-43. PubMed ID: 9550307
    [Abstract] [Full Text] [Related]

  • 26. Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
    Atalla A, Maser E.
    Toxicology; 1999 Nov 29; 139(1-2):155-66. PubMed ID: 10614696
    [Abstract] [Full Text] [Related]

  • 27. Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.
    Staretz ME, Koenig LA, Hecht SS.
    Carcinogenesis; 1997 Sep 29; 18(9):1715-22. PubMed ID: 9328166
    [Abstract] [Full Text] [Related]

  • 28. Evidence for an important role of DNA pyridyloxobutylation in rat lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: effects of dose and phenethyl isothiocyanate.
    Staretz ME, Foiles PG, Miglietta LM, Hecht SS.
    Cancer Res; 1997 Jan 15; 57(2):259-66. PubMed ID: 9000565
    [Abstract] [Full Text] [Related]

  • 29. Lung tumorigenicity of NNK given orally to A/J mice: its application to chemopreventive efficacy studies.
    Castonguay A, Pepin P, Stoner GD.
    Exp Lung Res; 1991 Jan 15; 17(2):485-99. PubMed ID: 2050045
    [Abstract] [Full Text] [Related]

  • 30. Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate.
    Hecht SS, Trushin N, Rigotty J, Carmella SG, Borukhova A, Akerkar S, Rivenson A.
    Cancer Epidemiol Biomarkers Prev; 1996 Aug 15; 5(8):645-52. PubMed ID: 8824368
    [Abstract] [Full Text] [Related]

  • 31. Effects of sulindac and oltipraz on the tumorigenicity of 4-(methylnitrosamino)1-(3-pyridyl)-1-butanone in A/J mouse lung.
    Pepin P, Bouchard L, Nicole P, Castonguay A.
    Carcinogenesis; 1992 Mar 15; 13(3):341-8. PubMed ID: 1547522
    [Abstract] [Full Text] [Related]

  • 32. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME, Murphy SE, Patten CJ, Nunes MG, Koehl W, Amin S, Koenig LA, Guengerich FP, Hecht SS.
    Drug Metab Dispos; 1997 Feb 15; 25(2):154-62. PubMed ID: 9029045
    [Abstract] [Full Text] [Related]

  • 33. Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.
    Belinsky SA, White CM, Trushin N, Hecht SS.
    Carcinogenesis; 1989 Dec 15; 10(12):2269-74. PubMed ID: 2591016
    [Abstract] [Full Text] [Related]

  • 34. Inhibition of liver microsomal cytochrome P450 activity and metabolism of the tobacco-specific nitrosamine NNK by capsaicin and ellagic acid.
    Zhang Z, Hamilton SM, Stewart C, Strother A, Teel RW.
    Anticancer Res; 1993 Dec 15; 13(6A):2341-6. PubMed ID: 8297156
    [Abstract] [Full Text] [Related]

  • 35. Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Zhou X, D'Agostino J, Xie F, Ding X.
    J Pharmacol Exp Ther; 2012 Apr 15; 341(1):233-41. PubMed ID: 22262919
    [Abstract] [Full Text] [Related]

  • 36. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 15; 17(4):809-13. PubMed ID: 8625495
    [Abstract] [Full Text] [Related]

  • 37. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.
    Smith GB, Bend JR, Bedard LL, Reid KR, Petsikas D, Massey TE.
    Drug Metab Dispos; 2003 Sep 15; 31(9):1134-41. PubMed ID: 12920169
    [Abstract] [Full Text] [Related]

  • 38. Effects of intragastrically administered Pycnogenol on NNK metabolism in F344 rats.
    Huynh HT, Teel RW.
    Anticancer Res; 1999 Sep 15; 19(3A):2095-9. PubMed ID: 10470154
    [Abstract] [Full Text] [Related]

  • 39. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K.
    Carcinogenesis; 1996 Apr 15; 17(4):749-53. PubMed ID: 8625486
    [Abstract] [Full Text] [Related]

  • 40. The essential role of the functional group in alkyl isothiocyanates for inhibition of tobacco nitrosamine-induced lung tumorigenesis.
    Jiao D, Smith TJ, Kim S, Yang CS, Desai D, Amin S, Chung FL.
    Carcinogenesis; 1996 Apr 15; 17(4):755-9. PubMed ID: 8625487
    [Abstract] [Full Text] [Related]

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