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Journal Abstract Search

135 related items for PubMed ID: 1447737

  • 1. Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 3. Pyridinylalkyl-substituted 8-[(arylsulfonyl)amino]octanoic acids.
    Main AJ, Bhagwat SS, Boswell C, Goldstein R, Gude C, Cohen DS, Furness P, Lee W, Louzan M.
    J Med Chem; 1992 Nov 13; 35(23):4366-72. PubMed ID: 1447737
    [Abstract] [Full Text] [Related]

  • 2. Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 4. 8-[[(4-Chlorophenyl)sulfonyl]amino]-4-(3-(3-pyridinyl) propyl)octanoic acid and analogs.
    Bhagwat SS, Gude C, Boswell C, Contardo N, Cohen DS, Dotson R, Mathis J, Lee W, Furness P, Zoganas H.
    J Med Chem; 1992 Nov 13; 35(23):4373-83. PubMed ID: 1447738
    [Abstract] [Full Text] [Related]

  • 3. Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 2. Synthesis and biological activity of 8-(benzenesulfonamido)-7-(3-pyridinyl)octaonic acid and related compounds.
    Main AJ, Goldstein R, Cohen DS, Furness P, Lee W.
    J Med Chem; 1992 Nov 13; 35(23):4362-5. PubMed ID: 1447736
    [Abstract] [Full Text] [Related]

  • 4. Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 5. Synthesis and evaluation of enantiomers of 8-[[(4-chlorophenyl)sulfonyl]amino]-4-(3-pyridinylalkyl)octanoic acid.
    Bhagwat SS, Gude C, Cohen DS, Dotson R, Mathis J, Lee W, Furness P.
    J Med Chem; 1993 Jan 22; 36(2):205-10. PubMed ID: 8423593
    [Abstract] [Full Text] [Related]

  • 5. Thromboxane modulating agents. 3. 1H-imidazol-1-ylalkyl- and 3-pyridinylalkyl-substituted 3-[2-[(arylsulfonyl)amino]ethyl]benzenepropanoic acid derivatives as dual thromboxane synthase inhibitor/thromboxane receptor antagonists.
    Dickinson RP, Dack KN, Long CJ, Steele J.
    J Med Chem; 1997 Oct 10; 40(21):3442-52. PubMed ID: 9341919
    [Abstract] [Full Text] [Related]

  • 6. Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane A2 receptor.
    Yu SM, Wu TS, Teng CM.
    Br J Pharmacol; 1994 Mar 10; 111(3):906-12. PubMed ID: 8019768
    [Abstract] [Full Text] [Related]

  • 7. Agents combining thromboxane receptor antagonism with thromboxane synthase inhibition: [[[2-(1H-imidazol-1-yl)ethylidene]amino]oxy]alkanoic acids.
    Cozzi P, Giordani A, Menichincheri M, Pillan A, Pinciroli V, Rossi A, Tonani R, Volpi D, Tamburin M, Ferrario R.
    J Med Chem; 1994 Oct 14; 37(21):3588-604. PubMed ID: 7932586
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and thromboxane A2 antagonistic activity of [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acid derivatives.
    Sakurai S, Ogawa N, Suzuki T, Kato K, Ohashi T, Yasuda S, Kato H, Ito Y.
    Chem Pharm Bull (Tokyo); 1996 Apr 14; 44(4):765-77. PubMed ID: 8681409
    [Abstract] [Full Text] [Related]

  • 9. Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11-cyclic carbonate derivatives of prostaglandin F2 alpha.
    Krauss AH, Woodward DF, Gibson LL, Protzman CE, Williams LS, Burk RM, Gac TS, Roof MB, Abbas F, Marshall K, Senior J.
    Br J Pharmacol; 1996 Mar 14; 117(6):1171-80. PubMed ID: 8882612
    [Abstract] [Full Text] [Related]

  • 10. The thromboxane A2/prostaglandin endoperoxide receptor antagonist activity of CV-4151, a thromboxane A2 synthetase inhibitor.
    Imura Y, Terashita Z, Shibouta Y, Nishikawa K.
    Eur J Pharmacol; 1988 Mar 15; 147(3):359-65. PubMed ID: 2967770
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and pharmacology of 3-substituted sodium azulene-1-sulfonates and related compounds: non-prostanoid thromboxane A2 receptor antagonists.
    Tomiyama T, Yokota M, Wakabayashi S, Kosakai K, Yanagisawa T.
    J Med Chem; 1993 Apr 02; 36(7):791-800. PubMed ID: 8464032
    [Abstract] [Full Text] [Related]

  • 12. Guanidine derivatives as combined thromboxane A2 receptor antagonists and synthase inhibitors.
    Soyka R, Guth BD, Weisenberger HM, Luger P, Müller TH.
    J Med Chem; 1999 Apr 08; 42(7):1235-49. PubMed ID: 10197967
    [Abstract] [Full Text] [Related]

  • 13. Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 1. (+/-)-(3-pyridinylbicycloheptyl)alkanoic acids.
    Bhagwat SS, Gude C, Cohen DS, Lee W, Furness P, Clarke FH.
    J Med Chem; 1991 Jun 08; 34(6):1790-7. PubMed ID: 1829485
    [Abstract] [Full Text] [Related]

  • 14. Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets.
    Watts IS, Wharton KA, White BP, Lumley P.
    Br J Pharmacol; 1991 Feb 08; 102(2):497-505. PubMed ID: 1826620
    [Abstract] [Full Text] [Related]

  • 15. Thromboxane synthase inhibitors suppress more effectively the aggregation of thromboxane receptor-desensitized than that of normal platelets: role of adenylylcyclase up-regulation.
    Vezza R, Nenci GG, Gresele P.
    J Pharmacol Exp Ther; 1995 Dec 08; 275(3):1497-505. PubMed ID: 8531121
    [Abstract] [Full Text] [Related]

  • 16. Pharmacological characterization of potent, long-acting thromboxane receptor antagonists, SQ 33,261 and SQ 33,552.
    Harris DN, Michel IM, Goldenberg HJ, Hartl KS, Allen GT, Steinbacher TE, Schumacher WA, Han WC, Hall SE, Floyd DM.
    J Pharmacol Exp Ther; 1992 Apr 08; 261(1):131-7. PubMed ID: 1532833
    [Abstract] [Full Text] [Related]

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  • 18. Synthesis and thromboxane A2/prostaglandin H2 receptor antagonistic activity of phenol derivatives.
    Fukumoto S, Shiraishi M, Terashita Z, Ashida Y, Inada Y.
    J Med Chem; 1992 Jun 12; 35(12):2202-9. PubMed ID: 1535377
    [Abstract] [Full Text] [Related]

  • 19. ZD1542, a potent thromboxane A2 synthase inhibitor and receptor antagonist in vitro.
    Brownlie RP, Brownrigg NJ, Butcher HM, Garcia R, Jessup R, Lee VJ, Tunstall S, Wayne MG.
    Br J Pharmacol; 1993 Dec 12; 110(4):1600-6. PubMed ID: 8306107
    [Abstract] [Full Text] [Related]

  • 20. Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 2.
    Ohshima E, Takami H, Sato H, Mohri S, Obase H, Miki I, Ishii A, Shirakura S, Karasawa A, Kubo K.
    J Med Chem; 1992 Sep 04; 35(18):3402-13. PubMed ID: 1388208
    [Abstract] [Full Text] [Related]

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