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160 related items for PubMed ID: 14500388

  • 1. Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism.
    Cullen JJ, Hinkhouse MM, Grady M, Gaut AW, Liu J, Zhang YP, Weydert CJ, Domann FE, Oberley LW.
    Cancer Res; 2003 Sep 01; 63(17):5513-20. PubMed ID: 14500388
    [Abstract] [Full Text] [Related]

  • 2. Treatment of pancreatic cancer cells with dicumarol induces cytotoxicity and oxidative stress.
    Lewis A, Ough M, Li L, Hinkhouse MM, Ritchie JM, Spitz DR, Cullen JJ.
    Clin Cancer Res; 2004 Jul 01; 10(13):4550-8. PubMed ID: 15240547
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinoma.
    Ough M, Lewis A, Zhang Y, Hinkhouse MM, Ritchie JM, Oberley LW, Cullen JJ.
    Free Radic Res; 2004 Nov 01; 38(11):1223-33. PubMed ID: 15621700
    [Abstract] [Full Text] [Related]

  • 4. 5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo.
    Dehn DL, Siegel D, Zafar KS, Reigan P, Swann E, Moody CJ, Ross D.
    Mol Cancer Ther; 2006 Jul 01; 5(7):1702-9. PubMed ID: 16891456
    [Abstract] [Full Text] [Related]

  • 5. The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma.
    Cullen JJ, Weydert C, Hinkhouse MM, Ritchie J, Domann FE, Spitz D, Oberley LW.
    Cancer Res; 2003 Mar 15; 63(6):1297-303. PubMed ID: 12649190
    [Abstract] [Full Text] [Related]

  • 6. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
    Qiu XB, Cadenas E.
    Arch Biochem Biophys; 1997 Oct 15; 346(2):241-51. PubMed ID: 9343371
    [Abstract] [Full Text] [Related]

  • 7. Evidence for NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated quinone-dependent redox cycling via plasma membrane electron transport: A sensitive cellular assay for NQO1.
    Tan AS, Berridge MV.
    Free Radic Biol Med; 2010 Feb 01; 48(3):421-9. PubMed ID: 19932748
    [Abstract] [Full Text] [Related]

  • 8. Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells.
    Reigan P, Colucci MA, Siegel D, Chilloux A, Moody CJ, Ross D.
    Biochemistry; 2007 May 22; 46(20):5941-50. PubMed ID: 17455910
    [Abstract] [Full Text] [Related]

  • 9. Activation of peroxisome proliferator-activated receptor gamma by troglitazone inhibits cell growth through the increase of p27KiP1 in human. Pancreatic carcinoma cells.
    Motomura W, Okumura T, Takahashi N, Obara T, Kohgo Y.
    Cancer Res; 2000 Oct 01; 60(19):5558-64. PubMed ID: 11034103
    [Abstract] [Full Text] [Related]

  • 10. Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
    Zhu ZW, Friess H, Wang L, Bogardus T, Korc M, Kleeff J, Büchler MW.
    Clin Cancer Res; 2001 Jan 01; 7(1):105-12. PubMed ID: 11205897
    [Abstract] [Full Text] [Related]

  • 11. Dicoumarol impairs mitochondrial electron transport and pyrimidine biosynthesis in human myeloid leukemia HL-60 cells.
    González-Aragón D, Ariza J, Villalba JM.
    Biochem Pharmacol; 2007 Feb 01; 73(3):427-39. PubMed ID: 17123468
    [Abstract] [Full Text] [Related]

  • 12. Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells.
    Du J, Daniels DH, Asbury C, Venkataraman S, Liu J, Spitz DR, Oberley LW, Cullen JJ.
    J Biol Chem; 2006 Dec 08; 281(49):37416-26. PubMed ID: 17040906
    [Abstract] [Full Text] [Related]

  • 13. Role of Nad(P)h: quinone oxidoreductase in the regulation of intracellular redox state.
    Mohora M.
    Rom J Intern Med; 2006 Dec 08; 38-39():33-50. PubMed ID: 15529570
    [Abstract] [Full Text] [Related]

  • 14. NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors.
    Han Y, Shen H, Carr BI, Wipf P, Lazo JS, Pan SS.
    J Pharmacol Exp Ther; 2004 Apr 08; 309(1):64-70. PubMed ID: 14718602
    [Abstract] [Full Text] [Related]

  • 15. NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger.
    Siegel D, Gustafson DL, Dehn DL, Han JY, Boonchoong P, Berliner LJ, Ross D.
    Mol Pharmacol; 2004 May 08; 65(5):1238-47. PubMed ID: 15102952
    [Abstract] [Full Text] [Related]

  • 16. p-nitrosophenol reduction by liver cytosol from ADH-positive and -negative deermice (Peromyscus maniculatus).
    Dudley BF, Winston GW.
    Arch Biochem Biophys; 1995 Feb 01; 316(2):879-85. PubMed ID: 7532387
    [Abstract] [Full Text] [Related]

  • 17. Modulation of reactive oxygen species in pancreatic cancer.
    Teoh ML, Sun W, Smith BJ, Oberley LW, Cullen JJ.
    Clin Cancer Res; 2007 Dec 15; 13(24):7441-50. PubMed ID: 18094428
    [Abstract] [Full Text] [Related]

  • 18. [Mitomycin C and its bioreduction: relevance of NAD(P)H: quinone oxidoreductase activity to mitomycin C-induced DNA damage and cytotoxicity].
    Nishiyama M, Saeki S, Aogi K, Hirabayashi N, Toge T.
    Gan To Kagaku Ryoho; 1993 Jun 15; 20(8):1037-41. PubMed ID: 7685584
    [Abstract] [Full Text] [Related]

  • 19. Role of NADPH cytochrome P450 reductase in activation of RH1.
    Begleiter A, Leith MK, Patel D, Hasinoff BB.
    Cancer Chemother Pharmacol; 2007 Oct 15; 60(5):713-23. PubMed ID: 17256129
    [Abstract] [Full Text] [Related]

  • 20. A novel plasma membrane quinone reductase and NAD(P)H:quinone oxidoreductase 1 are upregulated by serum withdrawal in human promyelocytic HL-60 cells.
    Forthoffer N, Gómez-Díaz C, Bello RI, Burón MI, Martín SF, Rodríguez-Aguilera JC, Navas P, Villalba JM.
    J Bioenerg Biomembr; 2002 Jun 15; 34(3):209-19. PubMed ID: 12171070
    [Abstract] [Full Text] [Related]

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