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364 related items for PubMed ID: 14500688

  • 1. Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells.
    Bharti AC, Donato N, Aggarwal BB.
    J Immunol; 2003 Oct 01; 171(7):3863-71. PubMed ID: 14500688
    [Abstract] [Full Text] [Related]

  • 2. Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).
    Chakravarti N, Myers JN, Aggarwal BB.
    Int J Cancer; 2006 Sep 15; 119(6):1268-75. PubMed ID: 16642480
    [Abstract] [Full Text] [Related]

  • 3. Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin.
    Gunaje JJ, Bhat GJ.
    Biochem Biophys Res Commun; 2001 Oct 19; 288(1):252-7. PubMed ID: 11594781
    [Abstract] [Full Text] [Related]

  • 4. Upregulated production of IL-6, but not IL-10, by interferon-alpha induces SOCS3 expression and attenuates STAT1 phosphorylation in myeloma cells.
    Usui E, Nishii K, Katayama N, Lorenzo V F, Chen F, Monma F, Otsuki T, Shiku H.
    Hematol J; 2004 Oct 19; 5(6):505-12. PubMed ID: 15570293
    [Abstract] [Full Text] [Related]

  • 5. A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
    Lin L, Benson DM, DeAngelis S, Bakan CE, Li PK, Li C, Lin J.
    Int J Cancer; 2012 Mar 15; 130(6):1459-69. PubMed ID: 21520044
    [Abstract] [Full Text] [Related]

  • 6. Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF beta is reversed by IL-15.
    Campbell JD, Cook G, Robertson SE, Fraser A, Boyd KS, Gracie JA, Franklin IM.
    J Immunol; 2001 Jul 01; 167(1):553-61. PubMed ID: 11418694
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway.
    Chen CW, Chang YH, Tsi CJ, Lin WW.
    J Immunol; 2003 Jul 15; 171(2):979-88. PubMed ID: 12847270
    [Abstract] [Full Text] [Related]

  • 8. JAK and STAT proteins are expressed and activated by IFN-gamma in rat pancreatic acinar cells.
    Gallmeier E, Schäfer C, Moubarak P, Tietz A, Plössl I, Huss R, Göke B, Wagner AC.
    J Cell Physiol; 2005 Apr 15; 203(1):209-16. PubMed ID: 15493010
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis.
    Alas S, Bonavida B.
    Clin Cancer Res; 2003 Jan 15; 9(1):316-26. PubMed ID: 12538484
    [Abstract] [Full Text] [Related]

  • 10. Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway.
    Li WQ, Dehnade F, Zafarullah M.
    J Immunol; 2001 Mar 01; 166(5):3491-8. PubMed ID: 11207308
    [Abstract] [Full Text] [Related]

  • 11. Cross-talk between interleukin 1beta (IL-1beta) and IL-6 signalling pathways: IL-1beta selectively inhibits IL-6-activated signal transducer and activator of transcription factor 1 (STAT1) by a proteasome-dependent mechanism.
    Shen X, Tian Z, Holtzman MJ, Gao B.
    Biochem J; 2000 Dec 15; 352 Pt 3(Pt 3):913-9. PubMed ID: 11104703
    [Abstract] [Full Text] [Related]

  • 12. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
    Wang LH, Kirken RA, Erwin RA, Yu CR, Farrar WL.
    J Immunol; 1999 Apr 01; 162(7):3897-904. PubMed ID: 10201908
    [Abstract] [Full Text] [Related]

  • 13. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.
    Kim HY, Park EJ, Joe EH, Jou I.
    J Immunol; 2003 Dec 01; 171(11):6072-9. PubMed ID: 14634121
    [Abstract] [Full Text] [Related]

  • 14. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells.
    Kirken RA, Erwin RA, Wang L, Wang Y, Rui H, Farrar WL.
    J Immunol; 2000 Nov 01; 165(9):5097-104. PubMed ID: 11046040
    [Abstract] [Full Text] [Related]

  • 15. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.
    Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030
    [Abstract] [Full Text] [Related]

  • 16. Interferon-alpha protects myeloma cell lines from dexamethasone-induced apoptosis.
    Liu P, Oken M, Van Ness B.
    Leukemia; 1999 Mar 28; 13(3):473-80. PubMed ID: 10086739
    [Abstract] [Full Text] [Related]

  • 17. Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-alpha.
    Yu CR, Lin JX, Fink DW, Akira S, Bloom ET, Yamauchi A.
    J Immunol; 1996 Jul 01; 157(1):126-37. PubMed ID: 8683106
    [Abstract] [Full Text] [Related]

  • 18. Activating mutations in STAT3 and STAT5 differentially affect cellular proliferation and apoptotic resistance in multiple myeloma cells.
    Hodge DR, Xiao W, Wang LH, Li D, Farrar WL.
    Cancer Biol Ther; 2004 Feb 01; 3(2):188-94. PubMed ID: 14726660
    [Abstract] [Full Text] [Related]

  • 19. Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis.
    Bharti AC, Shishodia S, Reuben JM, Weber D, Alexanian R, Raj-Vadhan S, Estrov Z, Talpaz M, Aggarwal BB.
    Blood; 2004 Apr 15; 103(8):3175-84. PubMed ID: 15070700
    [Abstract] [Full Text] [Related]

  • 20. The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.
    Smit LS, Meyer DJ, Billestrup N, Norstedt G, Schwartz J, Carter-Su C.
    Mol Endocrinol; 1996 May 15; 10(5):519-33. PubMed ID: 8732683
    [Abstract] [Full Text] [Related]

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