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355 related items for PubMed ID: 14500732

  • 1. Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D-forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system.
    Jia Y, Qi C, Zhang Z, Hashimoto T, Rao MS, Huyghe S, Suzuki Y, Van Veldhoven PP, Baes M, Reddy JK.
    J Biol Chem; 2003 Nov 21; 278(47):47232-9. PubMed ID: 14500732
    [Abstract] [Full Text] [Related]

  • 2. Absence of spontaneous peroxisome proliferation in enoyl-CoA Hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARalpha ligand metabolism.
    Qi C, Zhu Y, Pan J, Usuda N, Maeda N, Yeldandi AV, Rao MS, Hashimoto T, Reddy JK.
    J Biol Chem; 1999 May 28; 274(22):15775-80. PubMed ID: 10336479
    [Abstract] [Full Text] [Related]

  • 3. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha).
    Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ.
    J Biol Chem; 1998 Mar 06; 273(10):5678-84. PubMed ID: 9488698
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  • 4. Peroxisomal beta-oxidation and peroxisome proliferator-activated receptor alpha: an adaptive metabolic system.
    Reddy JK, Hashimoto T.
    Annu Rev Nutr; 2001 Mar 06; 21():193-230. PubMed ID: 11375435
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  • 5. Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype.
    Hashimoto T, Fujita T, Usuda N, Cook W, Qi C, Peters JM, Gonzalez FJ, Yeldandi AV, Rao MS, Reddy JK.
    J Biol Chem; 1999 Jul 02; 274(27):19228-36. PubMed ID: 10383430
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  • 7. Hepatic peroxisomal fatty acid beta-oxidation is regulated by liver X receptor alpha.
    Hu T, Foxworthy P, Siesky A, Ficorilli JV, Gao H, Li S, Christe M, Ryan T, Cao G, Eacho P, Michael MD, Michael LF.
    Endocrinology; 2005 Dec 02; 146(12):5380-7. PubMed ID: 16123164
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  • 9. Peroxisome-proliferator-activated receptors as physiological sensors of fatty acid metabolism: molecular regulation in peroxisomes.
    Latruffe N, Cherkaoui Malki M, Nicolas-Frances V, Jannin B, Clemencet MC, Hansmannel F, Passilly-Degrace P, Berlot JP.
    Biochem Soc Trans; 2001 May 02; 29(Pt 2):305-9. PubMed ID: 11356172
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  • 11. Elevated basal expression of liver peroxisomal beta-oxidation enzymes and CYP4A microsomal fatty acid omega-hydroxylase in STAT5b(-/-) mice: cross-talk in vivo between peroxisome proliferator-activated receptor and signal transducer and activator of transcription signaling pathways.
    Zhou YC, Davey HW, McLachlan MJ, Xie T, Waxman DJ.
    Toxicol Appl Pharmacol; 2002 Jul 01; 182(1):1-10. PubMed ID: 12127257
    [Abstract] [Full Text] [Related]

  • 12. Expression of peroxisome proliferator-activated receptor alpha, and PPARalpha regulated genes in spontaneously developed hepatocellular carcinomas in fatty acyl-CoA oxidase null mice.
    Meyer K, Jia Y, Cao WQ, Kashireddy P, Rao MS.
    Int J Oncol; 2002 Dec 01; 21(6):1175-80. PubMed ID: 12429965
    [Abstract] [Full Text] [Related]

  • 13. The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor alpha-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal beta-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase.
    Kassam A, Capone JP, Rachubinski RA.
    Mol Cell Endocrinol; 2001 May 15; 176(1-2):49-56. PubMed ID: 11369442
    [Abstract] [Full Text] [Related]

  • 14. Tamoxifen upregulates the peroxisomal β-oxidation enzyme Enoyl CoA hydratase and 3-hydroxyacyl CoA hydratase ameliorating hepatic lipid accumulation in mice.
    Zhang Z, Yang Q, Jin M, Wang J, Chai Y, Zhang L, Jiang Z, Yu Q.
    Int J Biochem Cell Biol; 2024 Jul 15; 172():106585. PubMed ID: 38734232
    [Abstract] [Full Text] [Related]

  • 15. Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis.
    Yeldandi AV, Rao MS, Reddy JK.
    Mutat Res; 2000 Mar 17; 448(2):159-77. PubMed ID: 10725470
    [Abstract] [Full Text] [Related]

  • 16. Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson.
    Lawrence JW, Li Y, Chen S, DeLuca JG, Berger JP, Umbenhauer DR, Moller DE, Zhou G.
    J Biol Chem; 2001 Aug 24; 276(34):31521-7. PubMed ID: 11418601
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  • 18. Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver.
    Jia Y, Qi C, Kashireddi P, Surapureddi S, Zhu YJ, Rao MS, Le Roith D, Chambon P, Gonzalez FJ, Reddy JK.
    J Biol Chem; 2004 Jun 04; 279(23):24427-34. PubMed ID: 15150259
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  • 20. Orphan nuclear hormone receptor RevErbalpha modulates expression from the promoter of the hydratase-dehydrogenase gene by inhibiting peroxisome proliferator-activated receptor alpha-dependent transactivation.
    Kassam A, Capone JP, Rachubinski RA.
    J Biol Chem; 1999 Aug 06; 274(32):22895-900. PubMed ID: 10428876
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