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256 related items for PubMed ID: 14503880

  • 1. Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions.
    Aitken SM, Kim DH, Kirsch JF.
    Biochemistry; 2003 Sep 30; 42(38):11297-306. PubMed ID: 14503880
    [Abstract] [Full Text] [Related]

  • 2. Kinetics of the yeast cystathionine beta-synthase forward and reverse reactions: continuous assays and the equilibrium constant for the reaction.
    Aitken SM, Kirsch JF.
    Biochemistry; 2003 Jan 21; 42(2):571-8. PubMed ID: 12525186
    [Abstract] [Full Text] [Related]

  • 3. Exploration of the active site of Escherichia coli cystathionine γ-synthase.
    Jaworski AF, Lodha PH, Manders AL, Aitken SM.
    Protein Sci; 2012 Nov 21; 21(11):1662-71. PubMed ID: 22855027
    [Abstract] [Full Text] [Related]

  • 4. The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
    Steegborn C, Messerschmidt A, Laber B, Streber W, Huber R, Clausen T.
    J Mol Biol; 1999 Jul 30; 290(5):983-96. PubMed ID: 10438597
    [Abstract] [Full Text] [Related]

  • 5. Reaction mechanism of Escherichia coli cystathionine gamma-synthase: direct evidence for a pyridoxamine derivative of vinylglyoxylate as a key intermediate in pyridoxal phosphate dependent gamma-elimination and gamma-replacement reactions.
    Brzović P, Holbrook EL, Greene RC, Dunn MF.
    Biochemistry; 1990 Jan 16; 29(2):442-51. PubMed ID: 2405904
    [Abstract] [Full Text] [Related]

  • 6. Development of a continuous assay and steady-state characterization of Escherichia coli threonine synthase.
    Morneau DJ, Abouassaf E, Skanes JE, Aitken SM.
    Anal Biochem; 2012 Apr 01; 423(1):78-85. PubMed ID: 22289691
    [Abstract] [Full Text] [Related]

  • 7. A role for glutamate-333 of Saccharomyces cerevisiae cystathionine γ-lyase as a determinant of specificity.
    Hopwood EM, Ahmed D, Aitken SM.
    Biochim Biophys Acta; 2014 Feb 01; 1844(2):465-72. PubMed ID: 24291053
    [Abstract] [Full Text] [Related]

  • 8. Enzymatic characterization and inhibitor discovery of a new cystathionine {gamma}-synthase from Helicobacter pylori.
    Kong Y, Wu D, Bai H, Han C, Chen J, Chen L, Hu L, Jiang H, Shen X.
    J Biochem; 2008 Jan 01; 143(1):59-68. PubMed ID: 17981822
    [Abstract] [Full Text] [Related]

  • 9. Exploration of structure-function relationships in Escherichia coli cystathionine γ-synthase and cystathionine β-lyase via chimeric constructs and site-specific substitutions.
    Manders AL, Jaworski AF, Ahmed M, Aitken SM.
    Biochim Biophys Acta; 2013 Jun 01; 1834(6):1044-53. PubMed ID: 23470500
    [Abstract] [Full Text] [Related]

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  • 12. Cystathionine gamma-synthase from Arabidopsis thaliana: purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli.
    Ravanel S, Gakière B, Job D, Douce R.
    Biochem J; 1998 Apr 15; 331 ( Pt 2)(Pt 2):639-48. PubMed ID: 9531508
    [Abstract] [Full Text] [Related]

  • 13. Methionine gamma-lyase: mechanistic deductions from the kinetic pH-effects. The role of the ionic state of a substrate in the enzymatic activity.
    Faleev NG, Alferov KV, Tsvetikova MA, Morozova EA, Revtovich SV, Khurs EN, Vorob'ev MM, Phillips RS, Demidkina TV, Khomutov RM.
    Biochim Biophys Acta; 2009 Oct 15; 1794(10):1414-20. PubMed ID: 19501676
    [Abstract] [Full Text] [Related]

  • 14. Structural Insights into Substrate Specificity of Cystathionine γ-Synthase from Corynebacterium glutamicum.
    Sagong HY, Kim KJ.
    J Agric Food Chem; 2017 Jul 26; 65(29):6002-6008. PubMed ID: 28675039
    [Abstract] [Full Text] [Related]

  • 15. Mechanistic studies with vinylglycine and beta-haloaminobutyrates as substrates for cystathionine gamma-synthetase from Salmonella typhimurium.
    Johnston M, Marcotte P, Donovan J, Walsh C.
    Biochemistry; 1979 May 01; 18(9):1729-38. PubMed ID: 373802
    [Abstract] [Full Text] [Related]

  • 16. Kinetic characterization of recombinant human cystathionine beta-synthase purified from E. coli.
    Belew MS, Quazi FI, Willmore WG, Aitken SM.
    Protein Expr Purif; 2009 Apr 01; 64(2):139-45. PubMed ID: 19010420
    [Abstract] [Full Text] [Related]

  • 17. In vivo analysis of various substrates utilized by cystathionine gamma-synthase and O-acetylhomoserine sulfhydrylase in methionine biosynthesis.
    Hacham Y, Gophna U, Amir R.
    Mol Biol Evol; 2003 Sep 01; 20(9):1513-20. PubMed ID: 12832650
    [Abstract] [Full Text] [Related]

  • 18. The hyperthermophilic cystathionine γ-synthase from the aerobic crenarchaeon Sulfolobus tokodaii: expression, purification, crystallization and structural insights.
    Sato D, Shiba T, Mizuno S, Kawamura A, Hanada S, Yamada T, Shinozaki M, Yanagitani M, Tamura T, Inagaki K, Harada S.
    Acta Crystallogr F Struct Biol Commun; 2017 Mar 01; 73(Pt 3):152-158. PubMed ID: 28291751
    [Abstract] [Full Text] [Related]

  • 19. Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution.
    Clausen T, Huber R, Prade L, Wahl MC, Messerschmidt A.
    EMBO J; 1998 Dec 01; 17(23):6827-38. PubMed ID: 9843488
    [Abstract] [Full Text] [Related]

  • 20. The enzymology of cystathionine biosynthesis: strategies for the control of substrate and reaction specificity.
    Aitken SM, Kirsch JF.
    Arch Biochem Biophys; 2005 Jan 01; 433(1):166-75. PubMed ID: 15581575
    [Abstract] [Full Text] [Related]

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