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220 related items for PubMed ID: 14514649

  • 1. Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes?
    Riedel MJ, Boora P, Steckley D, de Vries G, Light PE.
    Diabetes; 2003 Oct; 52(10):2630-5. PubMed ID: 14514649
    [Abstract] [Full Text] [Related]

  • 2. Saturated and cis/trans unsaturated acyl CoA esters differentially regulate wild-type and polymorphic beta-cell ATP-sensitive K+ channels.
    Riedel MJ, Light PE.
    Diabetes; 2005 Jul; 54(7):2070-9. PubMed ID: 15983208
    [Abstract] [Full Text] [Related]

  • 3. Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.
    Bränström R, Aspinwall CA, Välimäki S, Ostensson CG, Tibell A, Eckhard M, Brandhorst H, Corkey BE, Berggren PO, Larsson O.
    Diabetologia; 2004 Feb; 47(2):277-83. PubMed ID: 14740158
    [Abstract] [Full Text] [Related]

  • 4. Acyl coenzyme A esters differentially activate cardiac and beta-cell adenosine triphosphate-sensitive potassium channels in a side-chain length-specific manner.
    Fox JE, Magga J, Giles WR, Light PE.
    Metabolism; 2003 Oct; 52(10):1313-9. PubMed ID: 14564684
    [Abstract] [Full Text] [Related]

  • 5. Long chain coenzyme A esters activate the pore-forming subunit (Kir6. 2) of the ATP-regulated potassium channel.
    Bränström R, Leibiger IB, Leibiger B, Corkey BE, Berggren PO, Larsson O.
    J Biol Chem; 1998 Nov 20; 273(47):31395-400. PubMed ID: 9813050
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA.
    Gribble FM, Proks P, Corkey BE, Ashcroft FM.
    J Biol Chem; 1998 Oct 09; 273(41):26383-7. PubMed ID: 9756869
    [Abstract] [Full Text] [Related]

  • 7. Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.
    Bränström R, Leibiger IB, Leibiger B, Klement G, Nilsson J, Arhem P, Aspinwall CA, Corkey BE, Larsson O, Berggren PO.
    Diabetologia; 2007 Aug 09; 50(8):1670-7. PubMed ID: 17522836
    [Abstract] [Full Text] [Related]

  • 8. Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channels.
    Dabrowski M, Wahl P, Holmes WE, Ashcroft FM.
    Diabetologia; 2001 Jun 09; 44(6):747-56. PubMed ID: 11440368
    [Abstract] [Full Text] [Related]

  • 9. ATP-dependent potassium channels and type 2 diabetes mellitus.
    Bonfanti DH, Alcazar LP, Arakaki PA, Martins LT, Agustini BC, de Moraes Rego FG, Frigeri HR.
    Clin Biochem; 2015 May 09; 48(7-8):476-82. PubMed ID: 25583094
    [Abstract] [Full Text] [Related]

  • 10. Current status of the E23K Kir6.2 polymorphism: implications for type-2 diabetes.
    Riedel MJ, Steckley DC, Light PE.
    Hum Genet; 2005 Feb 09; 116(3):133-45. PubMed ID: 15565284
    [Abstract] [Full Text] [Related]

  • 11. Molecular biology of adenosine triphosphate-sensitive potassium channels.
    Aguilar-Bryan L, Bryan J.
    Endocr Rev; 1999 Apr 09; 20(2):101-35. PubMed ID: 10204114
    [Abstract] [Full Text] [Related]

  • 12. Palmitoylation of the KATP channel Kir6.2 subunit promotes channel opening by regulating PIP2 sensitivity.
    Yang HQ, Martinez-Ortiz W, Hwang J, Fan X, Cardozo TJ, Coetzee WA.
    Proc Natl Acad Sci U S A; 2020 May 12; 117(19):10593-10602. PubMed ID: 32332165
    [Abstract] [Full Text] [Related]

  • 13. Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.
    Cui Y, Tinker A, Clapp LH.
    Br J Pharmacol; 2003 May 12; 139(1):122-8. PubMed ID: 12746230
    [Abstract] [Full Text] [Related]

  • 14. Long-chain acyl-CoA esters and phosphatidylinositol phosphates modulate ATP inhibition of KATP channels by the same mechanism.
    Schulze D, Rapedius M, Krauter T, Baukrowitz T.
    J Physiol; 2003 Oct 15; 552(Pt 2):357-67. PubMed ID: 14561820
    [Abstract] [Full Text] [Related]

  • 15. Evidence for a unique long chain acyl-CoA ester binding site on the ATP-regulated potassium channel in mouse pancreatic beta cells.
    Bränström R, Corkey BE, Berggren PO, Larsson O.
    J Biol Chem; 1997 Jul 11; 272(28):17390-4. PubMed ID: 9211879
    [Abstract] [Full Text] [Related]

  • 16. Cytoplasmic terminus domains of Kir6.x confer different nucleotide-dependent gating on the ATP-sensitive K+ channel.
    Takano M, Xie LH, Otani H, Horie M.
    J Physiol; 1998 Oct 15; 512 ( Pt 2)(Pt 2):395-406. PubMed ID: 9763630
    [Abstract] [Full Text] [Related]

  • 17. Nateglinide, a D-phenylalanine derivative lacking either a sulfonylurea or benzamido moiety, specifically inhibits pancreatic beta-cell-type K(ATP) channels.
    Chachin M, Yamada M, Fujita A, Matsuoka T, Matsushita K, Kurachi Y.
    J Pharmacol Exp Ther; 2003 Mar 15; 304(3):1025-32. PubMed ID: 12604678
    [Abstract] [Full Text] [Related]

  • 18. Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.
    Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE.
    Endocrinology; 2008 Jul 15; 149(7):3679-87. PubMed ID: 18372336
    [Abstract] [Full Text] [Related]

  • 19. Regulated expression of adenosine triphosphate-sensitive potassium channel subunits in pancreatic beta-cells.
    Moritz W, Leech CA, Ferrer J, Habener JF.
    Endocrinology; 2001 Jan 15; 142(1):129-38. PubMed ID: 11145575
    [Abstract] [Full Text] [Related]

  • 20. Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.
    Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM.
    Diabetes; 2003 Feb 15; 52(2):568-72. PubMed ID: 12540637
    [Abstract] [Full Text] [Related]

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